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Short-Course Antimicrobial Therapy Outcomes for Intra-Abdominal Infection
Clinical question: Does a short, fixed duration of antibiotic therapy for complicated intra-abdominal infections lead to equivalent outcomes and...
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Post-Procedural Bridging Therapy for Secondary Prevention of VTE Increases Rate of Bleeding
Research Review: Post-Procedural Bridging Therapy and VTE Prevention
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Short-Course Antimicrobial Therapy Outcomes for Intraabdominal Infection
Research Review: Short-Course Antimicrobial Therapy for Intraabdominal Infection
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Effects of Peri-Operative Beta-Blockade in Noncardiac Surgery Vary Based on Cardiac Risk Factors
Research Review: Peri-Operative Beta-Blockade in Noncardiac Surgery
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Risk for In-Hospital Adverse Cardiac Events Low for Some Patients with Chest Pain
Clinical question: Do stable, low-risk patients hospitalized for chest pain after negative ED evaluation experience adverse cardiac events in the...
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New Strategy in Patients with Suspected Heparin-Induced Thrombocytopenia Improves Diagnostic Accuracy
Clinical question: Can a diagnostic strategy that utilizes a clinical prediction rule combined with an immunoassay appropriately guide management...
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Vasoactive Medications Safe in ICU via Peripheral Intravenous Access
Clinical question: Can vasoactive medications be safely given in the ICU via peripheral intravenous (PIV) access instead of central venous access...
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Cost, Frequency of Emergency Department Revisits Evaluated
Clinical question: What is the cost and frequency of ED revisits within three days and 30 days? Background: ED revisits lead to a financial and...
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Early, Late Hospital Readmission Factors Differ
Clinical question: What are the differences between factors associated with early (zero to seven days after discharge) and late (eight to 30 days...
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Patient Adherence to Pharmacological Thromboprophylaxis Improves with Interventions
Clinical question: How can patient adherence to pharmacological thromboprophylaxis be improved? Background: Prior studies suggest that the...
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Mortality Risk in Patients Older than 75 Presenting with Non-ST-Elevation Acute Coronary Syndrome
Clinical question: Is there a score that will predict the mortality rate in elderly patients presenting with a non-ST-elevation myocardial...
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Who Should Be Screened for HIV Infection?
Case A 31-year-old male with a history of asthma is admitted with an asthma exacerbation. He has no regular outpatient provider. He denies tobacco...
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Risk-Prediction Model Effective for Recurrent Clostridium Difficile Infection
Tool identifies infection risk factors at illness onset, predicts likelihood of recurrence
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Higher Mean Arterial Pressure in Septic Shock Patients Doesn’t Decrease Mortality
Mortality rates not significantly different in patients with septic shock randomized to higher MAP targets
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Infection Risk Decreases With Lower Red Blood Cell Transfusion Thresholds
Restrictive RBC transfusion guidelines associated with less risk of healthcare-acquired infections than liberal transfusion thresholds