News
Drug combos for psoriatic arthritis upped shingles risk
Key clinical point: Combining TNF-alpha inhibitors with conventional DMARDs more than doubled the risk of shingles in patients with psoriatic...
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Combo therapy didn’t top beta-lactams alone in most community-acquired pneumonia
Key clinical point: Beta-lactam monotherapy was noninferior to combined beta-lactam/macrolide therapy for adults with community-acquired...
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Prenatal BPA exposure linked to lung effects in 4-year-olds
Key clinical point: Prenatal exposure to bisphenol A was linked to decreased lung function in 4-year-olds. Major finding: Every 10-fold increase...
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Lungs donated after asphyxiation, drowning found suitable for transplant
Key clinical point: Lung transplant recipients had good outcomes and long-term survival in cases involving donors who died of asphyxiation or...
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Exposure-based therapy found superior for seniors with complicated grief
Key clinical point: Older adults with complicated grief were more than twice as likely to respond to targeted exposure therapy than to...
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Lower hemoglobin threshold did not affect outcomes in septic shock
Key clinical point: A hemoglobin transfusion threshold of 7 g/dL versus 9 g/dL did not affect outcomes in patients with septic shock. Major...
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Drug Combinations Found to Increase Upper Gastrointestinal Bleeding Risk
Key clinical point: Excess risk of upper gastrointestinal bleeding occurred with combinations of NSAIDs and selective serotonin reuptake...
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Model could cut CT scans of patients with Crohn’s disease by 43%
Key clinical point: A risk-stratification model could cut the use of computed tomography scans in emergency department patients with Crohn’s...
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Pediatric IBD rose by more than 40% in 15 years
Key clinical point: Although the steepest rise in inflammatory bowel disease occurred in children diagnosed before age 10 years, children...
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Drug combinations found to increase upper gastrointestinal bleeding risk
Key clinical point: Excess risk of upper gastrointestinal bleeding occurred with combinations of NSAIDs and selective serotonin reuptake...
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MicroRNA test improved preop pancreatic cancer diagnosis
Key clinical point: Cytology and a microRNA-based test were more sensitive than cytology alone in evaluating pancreatic cancer specimens obtained...
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Simvastatin shows no benefit for ARDS
Key clinical point: Simvastatin did not improve clinical outcomes in adults with acute respiratory distress syndrome. Major finding: The...
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High-dose treatment did not benefit ICU patients with vitamin D deficiency
Key clinical point: Vitamin D3 treatment did not reduce hospital length of stay or mortality in critically ill patients with vitamin D deficiency...
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Fenoldopam missed renal endpoint, caused hypotension in cardiac surgery patients
Key clinical point: Fenoldopam did not lessen early kidney injury after cardiac surgery and caused hypotension. Major finding: Fenoldopam did not...