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Tranexamic acid does not reduce risk of death in GI bleed
In patients with GI bleeding, does high-dose tranexamic acid (TXA) reduce the risk of death?
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Price transparency of laboratory testing does not change provider ordering habits
Clinical question: Does price transparency of laboratory tests at the point of order entry affect provider ordering behavior?
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Antibiotics after incision and drainage for simple abscesses improves outcomes
Clinical question: Does antibiotic administration after incision and drainage of simple abscesses improve cure rates?
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Postoperative Clostridium Difficile Infection Associated with Number of Antibiotics, Surgical Procedure Complexity
Clinical question: What are the factors that increase risk of Clostridium difficile infection (CDI) in postoperative patients? Background: CDI...
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Most Postoperative Readmissions Due to Patient Factors
Clinical question: What is the etiology of 30-day readmissions in postoperative patients? Background: As the focus of healthcare changes to a...
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Ischemic Hepatitis Associated with High Inpatient Mortality
Clinical question: What is the incidence and outcome of patients with ischemic hepatitis? Background: Ischemic hepatitis, or shock liver, is...
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AIMS65 Score Helps Predict Inpatient Mortality in Acute Upper Gastrointestinal Bleed
Clinical question: Does AIMS65 risk stratification score predict inpatient mortality in patients with acute upper gastrointestinal bleed (UGIB)?...
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No Mortality Benefit to Cardiac Catheterization in Patients with Stable Ischemic Heart Disease
Clinical question: Can cardiac catheterization prolong survival in patients with stable ischemic heart disease? Background: Previous results from...
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Increase in Broad-Spectrum Antibiotics Disproportionate to Rate of Resistant Organisms
Clinical question: Have healthcare-associated pneumonia (HCAP) guidelines improved treatment accuracy? Background: Guidelines released in 2005...
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Discontinuing Inhaled Corticosteroids in COPD Reduces Risk of Pneumonia
Clinical question: Is discontinuation of inhaled corticosteroids (ICSs) in patients with COPD associated with a decreased risk of pneumonia?...
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MEDS Score for Sepsis Might Best Predict ED Mortality
Clinical question: Which illness severity score best predicts outcomes in emergency department (ED) patients presenting with infection?...
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Continuous Chest Compressions Do Not Improve Outcome Compared to Chest Compressions Interrupted for Ventilation
Clinical question: In cardiopulmonary resuscitation, do continuous chest compressions improve survival or neurologic outcome compared to chest...
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ATRIA Better at Predicting Stroke Risk in Patients with Atrial Fibrillation Than CHADS2, CHA2DS2-VAS
Clinical question: Does the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) risk score more accurately identify patients with...