News
SIRS Criteria Could Identify More Patients with Severe Sepsis
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: Does inclusion of two or more SIRS criteria in the definition of severe sepsis accurately identify patients with higher...
News
Trimethoprim-Sulfamethoxazole Use in Older Patients Taking Spironolactone
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: Does trimethoprim-sulfamethoxazole (TMP-SMX) increase the risk of sudden death in older patients taking spironolactone?...
News
Medicare Nonpayment for Hospital-Acquired Conditions May Have Reduced Infection Rates
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: What was the effect of the Centers for Medicare and Medicaid Services’ (CMS) nonpayment for hospital-acquired conditions?...
News
Peri-Operative Phlebotomy Might Cause Significant Blood Loss in Cardiac Surgery Patients
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: What are the frequency of laboratory testing, the average total blood volume drawn per patient, and the resulting transfusion...
News
Clostridium Difficile Infection Rates in the U.S. in 2011
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: What are the incidence, recurrence rate, and mortality rate of Clostridium difficile infection (CDI) in the U.S.
News
CT Angiography Effect on Outcome for Patients with Symptomatic Chest Pain
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: Does CT angiography (CTA) improve clinical outcomes in patients with new-onset stable chest pain more than functional testing...
News
Early Goal-Directed Therapy for Sepsis Offers No Benefit Over Usual Care
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Background: Recent trials (ARISE, ProCESS) showed EGDT provided no mortality benefit over usual care. Questions remain about the effectiveness of...
News
NSAID Use by Patients on Antithrombotic Therapy Has Bleeding, Cardiovascular Risks
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: Is there increased risk of bleeding or cardiovascular events when using NSAIDs while on antithrombotic therapy for secondary...
News
Treatment of Patients with Atrial Fibrillation, Low CHA2DS2-VASc Scores
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: Is anticoagulation beneficial for patients with atrial fibrillation (Afib) and low CHA2DS2-VASc score (0 for men, 1 for women)...
News
Research Review: Ticagrelor for Post-Myocardial Infarction
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: Is ticagrelor for secondary prevention indicated for more than one year after myocardial infarction (MI)? Background: The...
News
Antibiotic Regimens Compared for Treating Uncomplicated Skin Infections
- Author:
- William J. Collins, MD
- Inpatient Specialty Program
- Cedars-Sinai
- Los Angeles
Clinical question: What are the efficacy and safety of clindamycin and trimethoprim-sulfamethoxazole (TMP-SMX) for treatment of uncomplicated...