News

Patient-based mouse MVID model hints at mechanism
- Author:
- Jim Kling
A method using gene editing at the two-cell stage recreated in mice the phenotype of a patient with two separate mutations.
News
Defensiveness may drive refusal for colon cancer screening
- Author:
- Jim Kling
An Irish study pinpoints excuses for putting off screening and discounting one’s risk of colorectal cancer.
News

An earlier hep B biomarker for clinical outcomes?
- Author:
- Jim Kling
Levels of a core-related antigen marker plunge years before a drop in the surface antigen, finds a natural history study of patients with chronic...
News

MS looks homogeneous
- Author:
- Jim Kling
An analysis of clinical factors and treatment responses calls for personal rather than precision medicine.
News

Portable MRI has potential for MS
- Author:
- Jim Kling
A blinded study showed good agreement with high-field MRI for some applications, but more development is needed.
News

A better MS measure?
- Author:
- Jim Kling
A ‘digital carpet’ may provide more granular information about functional decline in patients with MS.
News
MOGAD: Immunotherapy predicts fewer relapses
- Author:
- Jim Kling
IVIG therapy appears to be the most effective for reducing relapses.
News

To prevent MS, should we target EBV?
- Author:
- Jim Kling
Can a vaccine against EBV reduce MS incidence on a population level? Two experts debate.
News
Differential diagnosis in MS: What to watch for
- Author:
- Jim Kling
‘Red flags’ suggest something other than MS.
News
Use of diagnostic mammograms is inconsistent, survey finds
- Author:
- Jim Kling
Many employ diagnostic mammograms for posttreatment surveillance, but benefit is unknown.
News
Colorectal cancer treatment outcomes in older adults
- Author:
- Jim Kling
Disease-free survival boosted by adjuvant therapy completion, but only about half of patients finish.
News

Could boosting fat taste receptors help cut calories?
- Author:
- Jim Kling
In mice, fat taste receptor agonists added to food promoted satiation and weight loss.
News
Interval FITs could cut colonoscopies in those at above-average risk
- Author:
- Jim Kling
Two or more negative tests could suggest less need for colonoscopy at 5 years, especially in those with a family history of colon cancer.
News
Marriage rates declining for Canadian adolescent mothers?
- Author:
- Jim Kling
However, births to mothers younger than 18 years are rare in Canada, and births to married mothers in that age group are even rarer.
News
Double CF combination safe, effective in 1- to 2-year-olds
- Author:
- Jim Kling
Ivacaftor/lumacaftor combination could serve as a bridge to triple therapy.