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BOSTON — Depression, metabolic syndrome, and lack of exercise exacerbate daytime sleepiness in obese patients with sleep apnea, Dr. Alexios Sarrigiannidis said at the annual meeting of the Endocrine Society.
Dr. Sarrigiannidis and his colleagues in the Sleep Research and Treatment Center at Pennsylvania State University, Hershey, reviewed data for 708 consecutive patients, 470 men and 238 women, mean age 50 years, who had been referred for symptoms consistent with sleep apnea and had at least five episodes of apnea/hypopnea per hour. Mean body mass index was 34.9 kg/m
Participants completed the General Health Questionnaire; the Epworth Sleepiness Scale; and the Physical Activity Questionnaire. All were assessed for metabolic syndrome and underwent a standard, 8-hour nocturnal polysomnographic recording.
Among men, the mean apnea/hypopnea index score (representing the total number of either apnea or hypopnea episodes/hr of sleep) was 39.9, significantly higher than the 29.2 reported in the women. Measures of sleepiness and physical activity were similar for both groups.
Of the study population, 39% of the men and 62% of the women met the diagnostic criteria for major depressive disorder, and 69% of the men and 68% of the women fulfilled the criteria for metabolic syndrome. In both groups, about 43% did not get regular physical exercise.
Using logistic regression analysis, “exercise was the strongest [statistically significant] predictor of excess daytime sleepiness in men, followed by depression,” Dr. Sarrigiannidis reported in a poster presentation. “In the women, depression and metabolic syndrome, in that order, were the most important predictors.”
Independent of body weight, “participating in regular exercise appears to have somewhat of a protective effect in terms of daytime sleepiness, particularly among men,” Dr. Sarrigiannidis said. Exercise improves insulin resistance and reduces visceral adiposity, he said, noting that clinicians should encourage physical activity as a way to help combat daytime fatigue in individuals with sleep apnea.
BOSTON — Depression, metabolic syndrome, and lack of exercise exacerbate daytime sleepiness in obese patients with sleep apnea, Dr. Alexios Sarrigiannidis said at the annual meeting of the Endocrine Society.
Dr. Sarrigiannidis and his colleagues in the Sleep Research and Treatment Center at Pennsylvania State University, Hershey, reviewed data for 708 consecutive patients, 470 men and 238 women, mean age 50 years, who had been referred for symptoms consistent with sleep apnea and had at least five episodes of apnea/hypopnea per hour. Mean body mass index was 34.9 kg/m
Participants completed the General Health Questionnaire; the Epworth Sleepiness Scale; and the Physical Activity Questionnaire. All were assessed for metabolic syndrome and underwent a standard, 8-hour nocturnal polysomnographic recording.
Among men, the mean apnea/hypopnea index score (representing the total number of either apnea or hypopnea episodes/hr of sleep) was 39.9, significantly higher than the 29.2 reported in the women. Measures of sleepiness and physical activity were similar for both groups.
Of the study population, 39% of the men and 62% of the women met the diagnostic criteria for major depressive disorder, and 69% of the men and 68% of the women fulfilled the criteria for metabolic syndrome. In both groups, about 43% did not get regular physical exercise.
Using logistic regression analysis, “exercise was the strongest [statistically significant] predictor of excess daytime sleepiness in men, followed by depression,” Dr. Sarrigiannidis reported in a poster presentation. “In the women, depression and metabolic syndrome, in that order, were the most important predictors.”
Independent of body weight, “participating in regular exercise appears to have somewhat of a protective effect in terms of daytime sleepiness, particularly among men,” Dr. Sarrigiannidis said. Exercise improves insulin resistance and reduces visceral adiposity, he said, noting that clinicians should encourage physical activity as a way to help combat daytime fatigue in individuals with sleep apnea.
BOSTON — Depression, metabolic syndrome, and lack of exercise exacerbate daytime sleepiness in obese patients with sleep apnea, Dr. Alexios Sarrigiannidis said at the annual meeting of the Endocrine Society.
Dr. Sarrigiannidis and his colleagues in the Sleep Research and Treatment Center at Pennsylvania State University, Hershey, reviewed data for 708 consecutive patients, 470 men and 238 women, mean age 50 years, who had been referred for symptoms consistent with sleep apnea and had at least five episodes of apnea/hypopnea per hour. Mean body mass index was 34.9 kg/m
Participants completed the General Health Questionnaire; the Epworth Sleepiness Scale; and the Physical Activity Questionnaire. All were assessed for metabolic syndrome and underwent a standard, 8-hour nocturnal polysomnographic recording.
Among men, the mean apnea/hypopnea index score (representing the total number of either apnea or hypopnea episodes/hr of sleep) was 39.9, significantly higher than the 29.2 reported in the women. Measures of sleepiness and physical activity were similar for both groups.
Of the study population, 39% of the men and 62% of the women met the diagnostic criteria for major depressive disorder, and 69% of the men and 68% of the women fulfilled the criteria for metabolic syndrome. In both groups, about 43% did not get regular physical exercise.
Using logistic regression analysis, “exercise was the strongest [statistically significant] predictor of excess daytime sleepiness in men, followed by depression,” Dr. Sarrigiannidis reported in a poster presentation. “In the women, depression and metabolic syndrome, in that order, were the most important predictors.”
Independent of body weight, “participating in regular exercise appears to have somewhat of a protective effect in terms of daytime sleepiness, particularly among men,” Dr. Sarrigiannidis said. Exercise improves insulin resistance and reduces visceral adiposity, he said, noting that clinicians should encourage physical activity as a way to help combat daytime fatigue in individuals with sleep apnea.