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Featured Articles in the October 2014 Issue of The Journal of Thoracic and Cardiovascular Surgery

One of the primary features of the October issue of JTCVS is the topic of multiple arterial revascularization. This issue begins the study with an editorial and follows up with several articles on revascularization accompanied by commentaries. The next issue of Seminars in Thoracic and Cardiovascular Surgery will continue to highlight this topic through commentaries written by the authors of the revascularization papers listed below. Each commentary will discuss the content, results, and implications of the other papers. Multiple arterial grafting may be the next frontier for cardiac surgery.

Editorial

Courtesy of Mosby

Coronary bypass: Is it time to take the next step—the routine use of the second arterial graft?

Michael E. Halkos and Robert A. Guyton

In this issue, 3 studies from highly experienced coronary centers lend further support for a multiarterial grafting strategy. Graft patency and even long-term survival may be improved by this strategy. The evidence, although not level A, is persuasive; a second arterial graft should become routine in most cases.

Acquired Cardiovascular Disease

Total arterial revascularization with internal thoracic and radial artery grafts in triple-vessel coronary artery disease is associated with improved survival

Brian F. Buxton, William Y. Shi, James Tatoulis, John A. Fuller, Alexander Rosalion, and Philip A. Hayward

Total arterial revascularization using internal thoracic and radial artery conduits was associated with improved late survival in patients with 3-vessel coronary artery disease compared with conventional single internal thoracic and saphenous vein grafts. This benefit may result in superior graft patency and protection of the native circulation.

▶ Buxton and colleagues from Australia reviewed over 6,000 isolated CABG patients with 3 vessel CAD over a 15 year period (1995-2010) and propensity matched 384 pairs of patients with either all arterial grafting vs. the use of one IMA and SVG. They found a highly significant survival advantage at 15 years in the total arterial revascularization group vs. the one IMA with SVG group (Kaplan Meier, following multivariable Cox regression, and after propensity matching). The authors concluded that, “total arterial revascularization should be encouraged in patients with a reasonable life expectancy”. Interestingly, only 36% of patients had use of bilateral IMA grafts, 97% of patients had at least one radial artery graft (52% had single radial grafts and 48% had bilateral grafts), and only 51% of RIMA grafts were used in-situ. The authors highlighted the potential benefit derived from use of the radial artery graft. This article is of particular interest because it involved a large number of patients (propensity matched) over a 15 year period, and it nicely demonstrated a highly significant benefit to long term survival when arterial grafting was utilized. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

Editorial Commentary in JTCVS: Total arterial revascularization: When will its time come?

Todd K. Rosengart


The long-term impact of diabetes on graft patency after coronary artery bypass grafting surgery: A substudy of the multicenter Radial Artery Patency Study

Saswata Deb, Steve K. Singh, Fuad Moussa, Hideki Tsubota, Dai Une, Alex Kiss, George Tomlinson, Mehdi Afshar, Ryan Sless, Eric A. Cohen, Sam Radhakrishnan, James Dubbin, Leonard Schwartz, and Stephen E. Fremes on behalf of the Radial Artery Patency Study Investigators

Radial artery grafts compared with saphenous vein grafts were associated with a lower rate of late graft occlusion in diabetic patients after coronary artery bypass surgery. Predictors against late graft occlusion included the use of radial arteries and high-grade target vessel stenosis. The type of conduit and late occlusion were influenced by diabetic status.

▶ Deb and colleagues from Toronto, Ottawa, and Texas Heart Institute reviewed patency rates in 269 low risk (<80 yrs, elective, EF>35%) isolated CABG patients (with 3 vessel CAD) from the Radial Artery Patency Study (each patient underwent randomization dictating use of radial artery or vein graft to separate territories). Patients underwent diagnostic angiography (N=234) or CT angio (N=35) at least 5 years postoperatively. New data presented are long term (>5 yr) patency in diabetics. The authors noted that the proportion of complete graft occlusion was significantly lower in radial artery grafts vs. saphenous grafts in diabetics; however, it was similar in non-diabetics. Interestingly, there was no difference in the occlusion rate of the IMA graft in diabetics compared to non-diabetics. Multivariate modeling demonstrated female sex, smoking history, and elevated creatinine as increased risk factors for late graft occlusion; whereas use of the radial artery and high grade target stenosis (>90% vs. 70-89% stenosis) were protective. The authors concluded that the study supports the use of the radial artery as a second conduit is appropriate in diabetic patients. Using blinded angiographic follow-up, this study importantly supports the use of arterial grafting, and specifically the use of the radial artery, in diabetic patients. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

 

 

Editorial Commentary in JTCVS: Arterial grafting and the challenge of the patient with diabetes

Paul A. Kurlansky

Surgical revascularization techniques that minimize surgical risk and maximize late survival after coronary artery bypass grafting in patients with diabetes mellitus

Sajjad Raza, Joseph F. Sabik III, Khalil Masabni, Ponnuthurai Ainkaran, Bruce W. Lytle, and Eugene H. Blackstone

BITA grafting with complete revascularization maximized long-term survival and is recommended for patients with diabetes undergoing surgical revascularization. It should be used in all patients with diabetes whose risk of DSWI is low and might be best avoided in obese diabetic women with diffuse atherosclerotic burden.

▶ Raza and colleagues from the Cleveland Clinic reviewed over 11,922 diabetic isolated CABG patients over a 39 year period (1972-2011) and attempted to identify patients that would derive the greatest survival benefit from an optimal surgical technique by evaluating 12 possible surgical combinations (no use of IMA, use of one IMA, use of 2 IMA grafts, incomplete revascularization, complete revascularization, off-pump, and on- pump CABG). After adjusting for patient characteristics, use of 2 IMA grafts was better than one IMA graft (21% lower late mortality), two IMA grafts was associated with more deep sternal wound infections (yet this had a small effect on survival), and complete revascularization was associated with lower late mortality (10%) compared to incomplete revascularization. Interestingly, additional risks for deep sternal wound infection included: female sex, medically treated diabetes mellitus, peripheral artery disease, prior myocardial infarction, and higher BMI; and HgA1C was not. The authors concluded that the strategy with the best predicted survival was one including use of 2 IMA grafts, complete revascularization, and off-pump techniques. The worst strategy was one including no IMA grafts, incomplete revascularization, and on-pump techniques. They noted that the survival benefit associated with the best combination was largely due to the benefit of the use of 2 IMA grafts. This article importantly reinforces the known benefit to long term survival with the use of 2 IMA grafts over one in a very large cohort of diabetic patients. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

Editorial Commentary in JTCVS: Two internal thoracic arteries really are better

Andrea Carpenter

Readers who found these articles interesting may also like to read the following papers in recent and future issues of the JTCVS sister publications, Seminars in Thoracic and Cardiovascular Surgery and Operative Techniques in Thoracic and Cardiovascular Surgery.

Seminars

Discussion in Cardiothoracic Treatment and Care: Coronary Artery Bypass Grafting. John Puskas, Harold Lazar, Michael Mack, Joseph Sabik, David Taggart. Semin Thorac Cardiovasc Surg 2014 Spring; 26(1):75-94.

News and Views: Editorials on Multiple Arterial Grafting. Brian Buxton and Stephen Fremes (expected publication December 2014).

News and Views: Role of PCI in the Treatment of Left Main Coronary Disease. A. P. Kappetein. (expected publication December 2014).

State of the Art: Post-CABG antiplatelet therapy. Victor Ferraris (expected publication December 2014).

Operative Techniques

Repair of Postinfarct Ventricular Septal Defect: Anterior Apical Ventricular Septal Defect. John Conte. Oper Tech Thorac Cardiovasc Surg. 2014 Spring;19(1):96-114.

Repair of Postinfarction Ventricular Septal Defect: Posterior Inferior Ventricular Septal Defect.Thomas Gleason. Oper Tech Thorac Cardiovasc Surg. 2014 Spring; 19(1):115-126

Upcoming Issues of JTCVS

The November issue of JTCVS will feature editorials, articles, and commentaries on graft patency and long-term survival with off-pump CABG, cerebral protection during congenital heart surgery, and the current status of surgery for non-small cell lung cancer. December will include editorials, articles, and commentaries on cerebral protection during aortic surgery and CABG for poor LVF.

Articles in Press

Don’t forget to visit the Journal’s Articles in Press section at http://jtcvs.com/inpress. Articles appear online shortly after acceptance in their submitted format, which is replaced with the final formatted version once the authors have approved their proofs. Once an article goes online in the Articles in Press section it is indexed in Medline, fully searchable and citable before ever appearing in print. You can also sign up for the Articles in Press email alerts or RSS feed, much as you would sign up for an electronic table of contents alert for the print issue. Go to http://jtcvs.com/user/alerts/saveaipalert.

References

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One of the primary features of the October issue of JTCVS is the topic of multiple arterial revascularization. This issue begins the study with an editorial and follows up with several articles on revascularization accompanied by commentaries. The next issue of Seminars in Thoracic and Cardiovascular Surgery will continue to highlight this topic through commentaries written by the authors of the revascularization papers listed below. Each commentary will discuss the content, results, and implications of the other papers. Multiple arterial grafting may be the next frontier for cardiac surgery.

Editorial

Courtesy of Mosby

Coronary bypass: Is it time to take the next step—the routine use of the second arterial graft?

Michael E. Halkos and Robert A. Guyton

In this issue, 3 studies from highly experienced coronary centers lend further support for a multiarterial grafting strategy. Graft patency and even long-term survival may be improved by this strategy. The evidence, although not level A, is persuasive; a second arterial graft should become routine in most cases.

Acquired Cardiovascular Disease

Total arterial revascularization with internal thoracic and radial artery grafts in triple-vessel coronary artery disease is associated with improved survival

Brian F. Buxton, William Y. Shi, James Tatoulis, John A. Fuller, Alexander Rosalion, and Philip A. Hayward

Total arterial revascularization using internal thoracic and radial artery conduits was associated with improved late survival in patients with 3-vessel coronary artery disease compared with conventional single internal thoracic and saphenous vein grafts. This benefit may result in superior graft patency and protection of the native circulation.

▶ Buxton and colleagues from Australia reviewed over 6,000 isolated CABG patients with 3 vessel CAD over a 15 year period (1995-2010) and propensity matched 384 pairs of patients with either all arterial grafting vs. the use of one IMA and SVG. They found a highly significant survival advantage at 15 years in the total arterial revascularization group vs. the one IMA with SVG group (Kaplan Meier, following multivariable Cox regression, and after propensity matching). The authors concluded that, “total arterial revascularization should be encouraged in patients with a reasonable life expectancy”. Interestingly, only 36% of patients had use of bilateral IMA grafts, 97% of patients had at least one radial artery graft (52% had single radial grafts and 48% had bilateral grafts), and only 51% of RIMA grafts were used in-situ. The authors highlighted the potential benefit derived from use of the radial artery graft. This article is of particular interest because it involved a large number of patients (propensity matched) over a 15 year period, and it nicely demonstrated a highly significant benefit to long term survival when arterial grafting was utilized. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

Editorial Commentary in JTCVS: Total arterial revascularization: When will its time come?

Todd K. Rosengart


The long-term impact of diabetes on graft patency after coronary artery bypass grafting surgery: A substudy of the multicenter Radial Artery Patency Study

Saswata Deb, Steve K. Singh, Fuad Moussa, Hideki Tsubota, Dai Une, Alex Kiss, George Tomlinson, Mehdi Afshar, Ryan Sless, Eric A. Cohen, Sam Radhakrishnan, James Dubbin, Leonard Schwartz, and Stephen E. Fremes on behalf of the Radial Artery Patency Study Investigators

Radial artery grafts compared with saphenous vein grafts were associated with a lower rate of late graft occlusion in diabetic patients after coronary artery bypass surgery. Predictors against late graft occlusion included the use of radial arteries and high-grade target vessel stenosis. The type of conduit and late occlusion were influenced by diabetic status.

▶ Deb and colleagues from Toronto, Ottawa, and Texas Heart Institute reviewed patency rates in 269 low risk (<80 yrs, elective, EF>35%) isolated CABG patients (with 3 vessel CAD) from the Radial Artery Patency Study (each patient underwent randomization dictating use of radial artery or vein graft to separate territories). Patients underwent diagnostic angiography (N=234) or CT angio (N=35) at least 5 years postoperatively. New data presented are long term (>5 yr) patency in diabetics. The authors noted that the proportion of complete graft occlusion was significantly lower in radial artery grafts vs. saphenous grafts in diabetics; however, it was similar in non-diabetics. Interestingly, there was no difference in the occlusion rate of the IMA graft in diabetics compared to non-diabetics. Multivariate modeling demonstrated female sex, smoking history, and elevated creatinine as increased risk factors for late graft occlusion; whereas use of the radial artery and high grade target stenosis (>90% vs. 70-89% stenosis) were protective. The authors concluded that the study supports the use of the radial artery as a second conduit is appropriate in diabetic patients. Using blinded angiographic follow-up, this study importantly supports the use of arterial grafting, and specifically the use of the radial artery, in diabetic patients. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

 

 

Editorial Commentary in JTCVS: Arterial grafting and the challenge of the patient with diabetes

Paul A. Kurlansky

Surgical revascularization techniques that minimize surgical risk and maximize late survival after coronary artery bypass grafting in patients with diabetes mellitus

Sajjad Raza, Joseph F. Sabik III, Khalil Masabni, Ponnuthurai Ainkaran, Bruce W. Lytle, and Eugene H. Blackstone

BITA grafting with complete revascularization maximized long-term survival and is recommended for patients with diabetes undergoing surgical revascularization. It should be used in all patients with diabetes whose risk of DSWI is low and might be best avoided in obese diabetic women with diffuse atherosclerotic burden.

▶ Raza and colleagues from the Cleveland Clinic reviewed over 11,922 diabetic isolated CABG patients over a 39 year period (1972-2011) and attempted to identify patients that would derive the greatest survival benefit from an optimal surgical technique by evaluating 12 possible surgical combinations (no use of IMA, use of one IMA, use of 2 IMA grafts, incomplete revascularization, complete revascularization, off-pump, and on- pump CABG). After adjusting for patient characteristics, use of 2 IMA grafts was better than one IMA graft (21% lower late mortality), two IMA grafts was associated with more deep sternal wound infections (yet this had a small effect on survival), and complete revascularization was associated with lower late mortality (10%) compared to incomplete revascularization. Interestingly, additional risks for deep sternal wound infection included: female sex, medically treated diabetes mellitus, peripheral artery disease, prior myocardial infarction, and higher BMI; and HgA1C was not. The authors concluded that the strategy with the best predicted survival was one including use of 2 IMA grafts, complete revascularization, and off-pump techniques. The worst strategy was one including no IMA grafts, incomplete revascularization, and on-pump techniques. They noted that the survival benefit associated with the best combination was largely due to the benefit of the use of 2 IMA grafts. This article importantly reinforces the known benefit to long term survival with the use of 2 IMA grafts over one in a very large cohort of diabetic patients. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

Editorial Commentary in JTCVS: Two internal thoracic arteries really are better

Andrea Carpenter

Readers who found these articles interesting may also like to read the following papers in recent and future issues of the JTCVS sister publications, Seminars in Thoracic and Cardiovascular Surgery and Operative Techniques in Thoracic and Cardiovascular Surgery.

Seminars

Discussion in Cardiothoracic Treatment and Care: Coronary Artery Bypass Grafting. John Puskas, Harold Lazar, Michael Mack, Joseph Sabik, David Taggart. Semin Thorac Cardiovasc Surg 2014 Spring; 26(1):75-94.

News and Views: Editorials on Multiple Arterial Grafting. Brian Buxton and Stephen Fremes (expected publication December 2014).

News and Views: Role of PCI in the Treatment of Left Main Coronary Disease. A. P. Kappetein. (expected publication December 2014).

State of the Art: Post-CABG antiplatelet therapy. Victor Ferraris (expected publication December 2014).

Operative Techniques

Repair of Postinfarct Ventricular Septal Defect: Anterior Apical Ventricular Septal Defect. John Conte. Oper Tech Thorac Cardiovasc Surg. 2014 Spring;19(1):96-114.

Repair of Postinfarction Ventricular Septal Defect: Posterior Inferior Ventricular Septal Defect.Thomas Gleason. Oper Tech Thorac Cardiovasc Surg. 2014 Spring; 19(1):115-126

Upcoming Issues of JTCVS

The November issue of JTCVS will feature editorials, articles, and commentaries on graft patency and long-term survival with off-pump CABG, cerebral protection during congenital heart surgery, and the current status of surgery for non-small cell lung cancer. December will include editorials, articles, and commentaries on cerebral protection during aortic surgery and CABG for poor LVF.

Articles in Press

Don’t forget to visit the Journal’s Articles in Press section at http://jtcvs.com/inpress. Articles appear online shortly after acceptance in their submitted format, which is replaced with the final formatted version once the authors have approved their proofs. Once an article goes online in the Articles in Press section it is indexed in Medline, fully searchable and citable before ever appearing in print. You can also sign up for the Articles in Press email alerts or RSS feed, much as you would sign up for an electronic table of contents alert for the print issue. Go to http://jtcvs.com/user/alerts/saveaipalert.

One of the primary features of the October issue of JTCVS is the topic of multiple arterial revascularization. This issue begins the study with an editorial and follows up with several articles on revascularization accompanied by commentaries. The next issue of Seminars in Thoracic and Cardiovascular Surgery will continue to highlight this topic through commentaries written by the authors of the revascularization papers listed below. Each commentary will discuss the content, results, and implications of the other papers. Multiple arterial grafting may be the next frontier for cardiac surgery.

Editorial

Courtesy of Mosby

Coronary bypass: Is it time to take the next step—the routine use of the second arterial graft?

Michael E. Halkos and Robert A. Guyton

In this issue, 3 studies from highly experienced coronary centers lend further support for a multiarterial grafting strategy. Graft patency and even long-term survival may be improved by this strategy. The evidence, although not level A, is persuasive; a second arterial graft should become routine in most cases.

Acquired Cardiovascular Disease

Total arterial revascularization with internal thoracic and radial artery grafts in triple-vessel coronary artery disease is associated with improved survival

Brian F. Buxton, William Y. Shi, James Tatoulis, John A. Fuller, Alexander Rosalion, and Philip A. Hayward

Total arterial revascularization using internal thoracic and radial artery conduits was associated with improved late survival in patients with 3-vessel coronary artery disease compared with conventional single internal thoracic and saphenous vein grafts. This benefit may result in superior graft patency and protection of the native circulation.

▶ Buxton and colleagues from Australia reviewed over 6,000 isolated CABG patients with 3 vessel CAD over a 15 year period (1995-2010) and propensity matched 384 pairs of patients with either all arterial grafting vs. the use of one IMA and SVG. They found a highly significant survival advantage at 15 years in the total arterial revascularization group vs. the one IMA with SVG group (Kaplan Meier, following multivariable Cox regression, and after propensity matching). The authors concluded that, “total arterial revascularization should be encouraged in patients with a reasonable life expectancy”. Interestingly, only 36% of patients had use of bilateral IMA grafts, 97% of patients had at least one radial artery graft (52% had single radial grafts and 48% had bilateral grafts), and only 51% of RIMA grafts were used in-situ. The authors highlighted the potential benefit derived from use of the radial artery graft. This article is of particular interest because it involved a large number of patients (propensity matched) over a 15 year period, and it nicely demonstrated a highly significant benefit to long term survival when arterial grafting was utilized. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

Editorial Commentary in JTCVS: Total arterial revascularization: When will its time come?

Todd K. Rosengart


The long-term impact of diabetes on graft patency after coronary artery bypass grafting surgery: A substudy of the multicenter Radial Artery Patency Study

Saswata Deb, Steve K. Singh, Fuad Moussa, Hideki Tsubota, Dai Une, Alex Kiss, George Tomlinson, Mehdi Afshar, Ryan Sless, Eric A. Cohen, Sam Radhakrishnan, James Dubbin, Leonard Schwartz, and Stephen E. Fremes on behalf of the Radial Artery Patency Study Investigators

Radial artery grafts compared with saphenous vein grafts were associated with a lower rate of late graft occlusion in diabetic patients after coronary artery bypass surgery. Predictors against late graft occlusion included the use of radial arteries and high-grade target vessel stenosis. The type of conduit and late occlusion were influenced by diabetic status.

▶ Deb and colleagues from Toronto, Ottawa, and Texas Heart Institute reviewed patency rates in 269 low risk (<80 yrs, elective, EF>35%) isolated CABG patients (with 3 vessel CAD) from the Radial Artery Patency Study (each patient underwent randomization dictating use of radial artery or vein graft to separate territories). Patients underwent diagnostic angiography (N=234) or CT angio (N=35) at least 5 years postoperatively. New data presented are long term (>5 yr) patency in diabetics. The authors noted that the proportion of complete graft occlusion was significantly lower in radial artery grafts vs. saphenous grafts in diabetics; however, it was similar in non-diabetics. Interestingly, there was no difference in the occlusion rate of the IMA graft in diabetics compared to non-diabetics. Multivariate modeling demonstrated female sex, smoking history, and elevated creatinine as increased risk factors for late graft occlusion; whereas use of the radial artery and high grade target stenosis (>90% vs. 70-89% stenosis) were protective. The authors concluded that the study supports the use of the radial artery as a second conduit is appropriate in diabetic patients. Using blinded angiographic follow-up, this study importantly supports the use of arterial grafting, and specifically the use of the radial artery, in diabetic patients. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

 

 

Editorial Commentary in JTCVS: Arterial grafting and the challenge of the patient with diabetes

Paul A. Kurlansky

Surgical revascularization techniques that minimize surgical risk and maximize late survival after coronary artery bypass grafting in patients with diabetes mellitus

Sajjad Raza, Joseph F. Sabik III, Khalil Masabni, Ponnuthurai Ainkaran, Bruce W. Lytle, and Eugene H. Blackstone

BITA grafting with complete revascularization maximized long-term survival and is recommended for patients with diabetes undergoing surgical revascularization. It should be used in all patients with diabetes whose risk of DSWI is low and might be best avoided in obese diabetic women with diffuse atherosclerotic burden.

▶ Raza and colleagues from the Cleveland Clinic reviewed over 11,922 diabetic isolated CABG patients over a 39 year period (1972-2011) and attempted to identify patients that would derive the greatest survival benefit from an optimal surgical technique by evaluating 12 possible surgical combinations (no use of IMA, use of one IMA, use of 2 IMA grafts, incomplete revascularization, complete revascularization, off-pump, and on- pump CABG). After adjusting for patient characteristics, use of 2 IMA grafts was better than one IMA graft (21% lower late mortality), two IMA grafts was associated with more deep sternal wound infections (yet this had a small effect on survival), and complete revascularization was associated with lower late mortality (10%) compared to incomplete revascularization. Interestingly, additional risks for deep sternal wound infection included: female sex, medically treated diabetes mellitus, peripheral artery disease, prior myocardial infarction, and higher BMI; and HgA1C was not. The authors concluded that the strategy with the best predicted survival was one including use of 2 IMA grafts, complete revascularization, and off-pump techniques. The worst strategy was one including no IMA grafts, incomplete revascularization, and on-pump techniques. They noted that the survival benefit associated with the best combination was largely due to the benefit of the use of 2 IMA grafts. This article importantly reinforces the known benefit to long term survival with the use of 2 IMA grafts over one in a very large cohort of diabetic patients. [Summary and Comment by Dr. Jennifer Lawton, associate medical editor, Thoracic Surgery News].

Editorial Commentary in JTCVS: Two internal thoracic arteries really are better

Andrea Carpenter

Readers who found these articles interesting may also like to read the following papers in recent and future issues of the JTCVS sister publications, Seminars in Thoracic and Cardiovascular Surgery and Operative Techniques in Thoracic and Cardiovascular Surgery.

Seminars

Discussion in Cardiothoracic Treatment and Care: Coronary Artery Bypass Grafting. John Puskas, Harold Lazar, Michael Mack, Joseph Sabik, David Taggart. Semin Thorac Cardiovasc Surg 2014 Spring; 26(1):75-94.

News and Views: Editorials on Multiple Arterial Grafting. Brian Buxton and Stephen Fremes (expected publication December 2014).

News and Views: Role of PCI in the Treatment of Left Main Coronary Disease. A. P. Kappetein. (expected publication December 2014).

State of the Art: Post-CABG antiplatelet therapy. Victor Ferraris (expected publication December 2014).

Operative Techniques

Repair of Postinfarct Ventricular Septal Defect: Anterior Apical Ventricular Septal Defect. John Conte. Oper Tech Thorac Cardiovasc Surg. 2014 Spring;19(1):96-114.

Repair of Postinfarction Ventricular Septal Defect: Posterior Inferior Ventricular Septal Defect.Thomas Gleason. Oper Tech Thorac Cardiovasc Surg. 2014 Spring; 19(1):115-126

Upcoming Issues of JTCVS

The November issue of JTCVS will feature editorials, articles, and commentaries on graft patency and long-term survival with off-pump CABG, cerebral protection during congenital heart surgery, and the current status of surgery for non-small cell lung cancer. December will include editorials, articles, and commentaries on cerebral protection during aortic surgery and CABG for poor LVF.

Articles in Press

Don’t forget to visit the Journal’s Articles in Press section at http://jtcvs.com/inpress. Articles appear online shortly after acceptance in their submitted format, which is replaced with the final formatted version once the authors have approved their proofs. Once an article goes online in the Articles in Press section it is indexed in Medline, fully searchable and citable before ever appearing in print. You can also sign up for the Articles in Press email alerts or RSS feed, much as you would sign up for an electronic table of contents alert for the print issue. Go to http://jtcvs.com/user/alerts/saveaipalert.

References

References

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