October 2015 Quiz 1

ANSWER: A

Critique

Extrahepatic biliary atresia accounts for 25%-30% of children with neonatal cholestasis and it is the most commonly identified etiology. Despite the identification and ability to test for many other causes, idiopathic disease still accounts for a similar proportion of infants with cholestasis. Galactosemia, disorders of bile acid biosynthesis, and panhypopituitarism each account for 1% or slightly more of neonatal cholestasis. Autoimmune hepatitis is not a usual consideration in neonates.

Reference

Dellert S., Balistreri W., Neonatal cholestasis. In: Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Management, 3rd ed. Walker A., Durie P., Hamilton R., Walker–Smith J., eds. Hamilton, Ontario: B. C. Decker, 2000;52:880-94.

ANSWER: A

Critique

Extrahepatic biliary atresia accounts for 25%-30% of children with neonatal cholestasis and it is the most commonly identified etiology. Despite the identification and ability to test for many other causes, idiopathic disease still accounts for a similar proportion of infants with cholestasis. Galactosemia, disorders of bile acid biosynthesis, and panhypopituitarism each account for 1% or slightly more of neonatal cholestasis. Autoimmune hepatitis is not a usual consideration in neonates.

Reference

Dellert S., Balistreri W., Neonatal cholestasis. In: Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Management, 3rd ed. Walker A., Durie P., Hamilton R., Walker–Smith J., eds. Hamilton, Ontario: B. C. Decker, 2000;52:880-94.

ANSWER: A

Critique

Extrahepatic biliary atresia accounts for 25%-30% of children with neonatal cholestasis and it is the most commonly identified etiology. Despite the identification and ability to test for many other causes, idiopathic disease still accounts for a similar proportion of infants with cholestasis. Galactosemia, disorders of bile acid biosynthesis, and panhypopituitarism each account for 1% or slightly more of neonatal cholestasis. Autoimmune hepatitis is not a usual consideration in neonates.

Reference

Dellert S., Balistreri W., Neonatal cholestasis. In: Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Management, 3rd ed. Walker A., Durie P., Hamilton R., Walker–Smith J., eds. Hamilton, Ontario: B. C. Decker, 2000;52:880-94.