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MINNEAPOLIS — The use of oral antibiotics along with mechanical bowel preparation before colon resection significantly reduced the number of superficial surgical site infections, compared with the use of mechanical bowel preparation alone, according to the results of a retrospective study of 227 patients.
Superficial surgical site infections occurred in 3% of patients who were given oral antibiotics along with mechanical bowel preparation (MBP) vs. 11% of those who had MBP alone. There were also trends toward fewer deep surgical site infections, organ space surgical site infections, and anastomotic leaks, Dr. Khaled El-Badawi reported at the meeting.
The researchers performed a retrospective review of all elective segmental colon resections performed between 2007 and 2009. Patients were grouped by whether oral antibiotics had been used in conjunction with MBP. A total of 125 patients underwent MBP alone and 102 underwent MBP with oral antibiotics.
All patients were restricted to a clear liquid diet for at least 24 hours prior to surgery, and were also given 20 mg of bisacodyl and polyethylene glycol. Patients in the antibiotic group also received three doses of 1 g neomycin and 750 mg metronidazole on the day before surgery. Within 1 hour of surgical incision, all patients received 1 g ertapenem.
Dr. El-Badawi, who is a surgical resident at Grand Rapids Medical Education Partners in Michigan, noted that there was a significant difference between the two groups in terms of operative time: 154 minutes for the MBP-alone group vs. 125 minutes for the antibiotics and MBP group.
Disclosures: Dr. El-Badawi reported that he had no relevant financial relationships.
MINNEAPOLIS — The use of oral antibiotics along with mechanical bowel preparation before colon resection significantly reduced the number of superficial surgical site infections, compared with the use of mechanical bowel preparation alone, according to the results of a retrospective study of 227 patients.
Superficial surgical site infections occurred in 3% of patients who were given oral antibiotics along with mechanical bowel preparation (MBP) vs. 11% of those who had MBP alone. There were also trends toward fewer deep surgical site infections, organ space surgical site infections, and anastomotic leaks, Dr. Khaled El-Badawi reported at the meeting.
The researchers performed a retrospective review of all elective segmental colon resections performed between 2007 and 2009. Patients were grouped by whether oral antibiotics had been used in conjunction with MBP. A total of 125 patients underwent MBP alone and 102 underwent MBP with oral antibiotics.
All patients were restricted to a clear liquid diet for at least 24 hours prior to surgery, and were also given 20 mg of bisacodyl and polyethylene glycol. Patients in the antibiotic group also received three doses of 1 g neomycin and 750 mg metronidazole on the day before surgery. Within 1 hour of surgical incision, all patients received 1 g ertapenem.
Dr. El-Badawi, who is a surgical resident at Grand Rapids Medical Education Partners in Michigan, noted that there was a significant difference between the two groups in terms of operative time: 154 minutes for the MBP-alone group vs. 125 minutes for the antibiotics and MBP group.
Disclosures: Dr. El-Badawi reported that he had no relevant financial relationships.
MINNEAPOLIS — The use of oral antibiotics along with mechanical bowel preparation before colon resection significantly reduced the number of superficial surgical site infections, compared with the use of mechanical bowel preparation alone, according to the results of a retrospective study of 227 patients.
Superficial surgical site infections occurred in 3% of patients who were given oral antibiotics along with mechanical bowel preparation (MBP) vs. 11% of those who had MBP alone. There were also trends toward fewer deep surgical site infections, organ space surgical site infections, and anastomotic leaks, Dr. Khaled El-Badawi reported at the meeting.
The researchers performed a retrospective review of all elective segmental colon resections performed between 2007 and 2009. Patients were grouped by whether oral antibiotics had been used in conjunction with MBP. A total of 125 patients underwent MBP alone and 102 underwent MBP with oral antibiotics.
All patients were restricted to a clear liquid diet for at least 24 hours prior to surgery, and were also given 20 mg of bisacodyl and polyethylene glycol. Patients in the antibiotic group also received three doses of 1 g neomycin and 750 mg metronidazole on the day before surgery. Within 1 hour of surgical incision, all patients received 1 g ertapenem.
Dr. El-Badawi, who is a surgical resident at Grand Rapids Medical Education Partners in Michigan, noted that there was a significant difference between the two groups in terms of operative time: 154 minutes for the MBP-alone group vs. 125 minutes for the antibiotics and MBP group.
Disclosures: Dr. El-Badawi reported that he had no relevant financial relationships.