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Adhering to endocrine therapy is hard. What can be done?
Given the array of potential obstacles to endocrine therapy adherence, improving long-term use may be equally complex.
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Tirzepatide superior to semaglutide for A1c control, weight loss
“Although the efficacy of the high tirzepatide dose might make it a favorable choice, its real-world application can be affected on an individual’...
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Thyroid ablation safety addressed by expert consensus
“Probably the greatest concern shared by the writing group on this statement was the potential for clinicians to start ablation practices without...
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BCR is unreliable surrogate for overall survival in prostate cancer
The correlation between BCR-free survival and overall survival ranged from low to moderate.
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Financial toxicity screening can reduce cancer cost burdens
About one in five cancer survivors report experiencing financial toxicity, but financial monitoring is not a routine part of clinical care.
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Hemophilia: Concizumab lessens bleeding, could expand treatment options
The subcutaneous drug concizumab could be an important first treatment for hemophilia B with inhibitors; FDA resubmission is planned.
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Post-SCT, better survival in children with healthy gut diversity
After donor stem cell transplants, children with lower gut microbiota diversity show poorer survival and more complications.
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Can caffeine improve thyroid function?
The authors speculate that caffeine could potentially affect thyroid activity by affecting pituitary function.
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SCD: Survival disparities seen across insurance types
Nationwide study on sickle cell disease shows life expectancy remains shortened in adulthood, though improved for child patients.
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Postpartum depression risk increased among sexual minority women
Women identifying as sexual minorities show increases in postpartum depression, yet rates of reporting sexual orientation are low.
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Antibody shows promise in preventing GVHD
In translational research that shows potential for humans, an antibody blockade of the Notch signaling pathway prevents graft-versus-host-disease...
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Vegetarian diets can improve high-risk cardiovascular disease
“This meta-analysis is the first that generates evidence from randomized controlled trials to assess the association of vegetarian diets with...
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T3 in hypothyroidism gets extra recommendation: British medical groups
The ongoing debate over the use of LT3/LT4 combination therapy has persisted for more than 2 decades.
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New cancer survival calculator focuses on oral cancer
The broader aim of developing the tool is for this new approach to be “applicable for developing future prognostic models of cancer and noncancer...
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Quizartinib boosts AML survival, regardless of SCT
The FLT-inhibitor drug shows survival benefits in patients with higher-risk FLT3 mutations, with or without prior stem cell transplant.