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Key clinical point: The prevalence of exocrine pancreatic insufficiency (EPI) was higher in patients with diffuse echogenicity of the pancreas on endoscopic ultrasound (EUS; fatty pancreas group) vs patients with chronic diarrhea without known pancreatic disease (control group). This indicates that the EUS finding of diffuse echogenicity of the pancreas may have clinical implications on pancreatic function.
Major finding: The incidence of EPI (47% vs 6%) and chronic pancreatitis (18% vs 0%) was significantly higher (both P less than .001) in the fatty pancreas group vs control group. EPI was significantly associated with smoking (odds ratio [OR], 2.26; P = .018) and nonalcoholic fatty liver disease (OR, 4.00; P = .036) but not with chronic pancreatitis (OR, 0.70; P = .60).
Study details: Findings are from a retrospective analysis of 166 adult patients (fatty pancreas, n=89; control, n=77).
Disclosures: No source of funding was identified. MO Othman and I Raijman reported ties with various pharmaceutical companies. Other authors declared no conflict of interests.
Source: Krill JT et al. Dig Dis Sci. 2021 Aug 4. doi: 10.1007/s10620-021-07181-1
Key clinical point: The prevalence of exocrine pancreatic insufficiency (EPI) was higher in patients with diffuse echogenicity of the pancreas on endoscopic ultrasound (EUS; fatty pancreas group) vs patients with chronic diarrhea without known pancreatic disease (control group). This indicates that the EUS finding of diffuse echogenicity of the pancreas may have clinical implications on pancreatic function.
Major finding: The incidence of EPI (47% vs 6%) and chronic pancreatitis (18% vs 0%) was significantly higher (both P less than .001) in the fatty pancreas group vs control group. EPI was significantly associated with smoking (odds ratio [OR], 2.26; P = .018) and nonalcoholic fatty liver disease (OR, 4.00; P = .036) but not with chronic pancreatitis (OR, 0.70; P = .60).
Study details: Findings are from a retrospective analysis of 166 adult patients (fatty pancreas, n=89; control, n=77).
Disclosures: No source of funding was identified. MO Othman and I Raijman reported ties with various pharmaceutical companies. Other authors declared no conflict of interests.
Source: Krill JT et al. Dig Dis Sci. 2021 Aug 4. doi: 10.1007/s10620-021-07181-1
Key clinical point: The prevalence of exocrine pancreatic insufficiency (EPI) was higher in patients with diffuse echogenicity of the pancreas on endoscopic ultrasound (EUS; fatty pancreas group) vs patients with chronic diarrhea without known pancreatic disease (control group). This indicates that the EUS finding of diffuse echogenicity of the pancreas may have clinical implications on pancreatic function.
Major finding: The incidence of EPI (47% vs 6%) and chronic pancreatitis (18% vs 0%) was significantly higher (both P less than .001) in the fatty pancreas group vs control group. EPI was significantly associated with smoking (odds ratio [OR], 2.26; P = .018) and nonalcoholic fatty liver disease (OR, 4.00; P = .036) but not with chronic pancreatitis (OR, 0.70; P = .60).
Study details: Findings are from a retrospective analysis of 166 adult patients (fatty pancreas, n=89; control, n=77).
Disclosures: No source of funding was identified. MO Othman and I Raijman reported ties with various pharmaceutical companies. Other authors declared no conflict of interests.
Source: Krill JT et al. Dig Dis Sci. 2021 Aug 4. doi: 10.1007/s10620-021-07181-1