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Key clinical point: Fetuses classified postnatally as small for gestational age (SGA) and fetal growth restricted (FGR) had smaller prenatal cardiovascular biometrics already at the second trimester anatomy scan.
Major finding: Compared with the control fetus, the SGA group had significantly smaller ascending aorta in the 3-vessel view, whereas the FGR group had significantly smaller aortic valve and pulmonary valve, even after adjusting for gestational age and abdominal circumference (all P < .005).
Study details: Findings are from a sub-study of Copenhagen Baby Heart Study, a prospective study, including 8,278 fetuses from the second trimester of pregnancy, of which 625 were classified as SGA and 289 as FGR postnatally.
Disclosures: The study was supported by funding from “Rigshospitalets Research Foundation” and “Aase and EjnarDanielsens Research Foundation” received by C Vedel. OB Petersen declared holding a professorship funded by the Novo Nordisk Foundation. None of the other authors declared any conflict of interests.
Source: Frandsen JS et al. Am J Obstet Gynecol. 2021 Dec 20. doi: 10.1016/j.ajog.2021.12.031.
Key clinical point: Fetuses classified postnatally as small for gestational age (SGA) and fetal growth restricted (FGR) had smaller prenatal cardiovascular biometrics already at the second trimester anatomy scan.
Major finding: Compared with the control fetus, the SGA group had significantly smaller ascending aorta in the 3-vessel view, whereas the FGR group had significantly smaller aortic valve and pulmonary valve, even after adjusting for gestational age and abdominal circumference (all P < .005).
Study details: Findings are from a sub-study of Copenhagen Baby Heart Study, a prospective study, including 8,278 fetuses from the second trimester of pregnancy, of which 625 were classified as SGA and 289 as FGR postnatally.
Disclosures: The study was supported by funding from “Rigshospitalets Research Foundation” and “Aase and EjnarDanielsens Research Foundation” received by C Vedel. OB Petersen declared holding a professorship funded by the Novo Nordisk Foundation. None of the other authors declared any conflict of interests.
Source: Frandsen JS et al. Am J Obstet Gynecol. 2021 Dec 20. doi: 10.1016/j.ajog.2021.12.031.
Key clinical point: Fetuses classified postnatally as small for gestational age (SGA) and fetal growth restricted (FGR) had smaller prenatal cardiovascular biometrics already at the second trimester anatomy scan.
Major finding: Compared with the control fetus, the SGA group had significantly smaller ascending aorta in the 3-vessel view, whereas the FGR group had significantly smaller aortic valve and pulmonary valve, even after adjusting for gestational age and abdominal circumference (all P < .005).
Study details: Findings are from a sub-study of Copenhagen Baby Heart Study, a prospective study, including 8,278 fetuses from the second trimester of pregnancy, of which 625 were classified as SGA and 289 as FGR postnatally.
Disclosures: The study was supported by funding from “Rigshospitalets Research Foundation” and “Aase and EjnarDanielsens Research Foundation” received by C Vedel. OB Petersen declared holding a professorship funded by the Novo Nordisk Foundation. None of the other authors declared any conflict of interests.
Source: Frandsen JS et al. Am J Obstet Gynecol. 2021 Dec 20. doi: 10.1016/j.ajog.2021.12.031.