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Key clinical point: Compared with the control diet, a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) reduced the abundance of Bifidobacteria in the colonic microbiome of patients with irritable bowel syndrome (IBS), with no significant impact on other microbiome metrics.
Major finding: Overall, a low FODMAP diet had no clear impact on the microbiome biodiversity, total fecal short-chain fatty acid concentration (P = .20), and fecal pH (P = .14) compared with the control diet, but it was consistently associated with a reduced abundance of Bifidobacteria in the colonic microbiome.
Study details: Findings are from a systematic review and meta-analysis of 9 randomized controlled trials and 1 secondary publication including 403 patients with IBS who received a low FODMAP or control diet.
Disclosures: This study did not receive any funding. D So declared working in a department benefitting from the sales of a digital application and booklets on a low FODMAP diet.
Source: So D et al. Effects of a low FODMAP diet on the colonic microbiome in irritable bowel syndrome: A systematic review with meta-analysis. Am J Clin Nutr. 2022 (Jun 21). Doi: 10.1093/ajcn/nqac176
Key clinical point: Compared with the control diet, a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) reduced the abundance of Bifidobacteria in the colonic microbiome of patients with irritable bowel syndrome (IBS), with no significant impact on other microbiome metrics.
Major finding: Overall, a low FODMAP diet had no clear impact on the microbiome biodiversity, total fecal short-chain fatty acid concentration (P = .20), and fecal pH (P = .14) compared with the control diet, but it was consistently associated with a reduced abundance of Bifidobacteria in the colonic microbiome.
Study details: Findings are from a systematic review and meta-analysis of 9 randomized controlled trials and 1 secondary publication including 403 patients with IBS who received a low FODMAP or control diet.
Disclosures: This study did not receive any funding. D So declared working in a department benefitting from the sales of a digital application and booklets on a low FODMAP diet.
Source: So D et al. Effects of a low FODMAP diet on the colonic microbiome in irritable bowel syndrome: A systematic review with meta-analysis. Am J Clin Nutr. 2022 (Jun 21). Doi: 10.1093/ajcn/nqac176
Key clinical point: Compared with the control diet, a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) reduced the abundance of Bifidobacteria in the colonic microbiome of patients with irritable bowel syndrome (IBS), with no significant impact on other microbiome metrics.
Major finding: Overall, a low FODMAP diet had no clear impact on the microbiome biodiversity, total fecal short-chain fatty acid concentration (P = .20), and fecal pH (P = .14) compared with the control diet, but it was consistently associated with a reduced abundance of Bifidobacteria in the colonic microbiome.
Study details: Findings are from a systematic review and meta-analysis of 9 randomized controlled trials and 1 secondary publication including 403 patients with IBS who received a low FODMAP or control diet.
Disclosures: This study did not receive any funding. D So declared working in a department benefitting from the sales of a digital application and booklets on a low FODMAP diet.
Source: So D et al. Effects of a low FODMAP diet on the colonic microbiome in irritable bowel syndrome: A systematic review with meta-analysis. Am J Clin Nutr. 2022 (Jun 21). Doi: 10.1093/ajcn/nqac176