January 2019 Question 2

A 54-year-old woman presents for management of moderately severe ileocolonic Crohn’s disease. She has a strong family history of multiple sclerosis and recently noted some tingling in her toes for which she is undergoing neurologic evaluation. She has had two small basal cell carcinomas removed from her cheek in the last year. She received the BCG vaccine as a child and had a positive PPD skin test within the last year. Laboratory evaluation reveals HBsAg negative, anti-HBs positive, and anti-HBc positive; JC virus antibody is positive.