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Key clinical point: This meta-analysis demonstrated a significant bidirectional association between psoriasis and migraine, with greater severity of psoriasis being associated with an increasingly higher risk of developing migraine.
Major finding: Presence vs absence of psoriasis was associated with 1.69-fold higher odds of prevalent migraine (pooled odds ratio [OR] 1.69; 95% CI 1.26-2.28), with the risk for incident migraine being significantly higher in patients with mild (incidence rate ratio [IRR] 1.37; 95% CI 1.30-1.44) and severe (IRR 1.55; 95% CI 1.29-1.86) psoriasis and psoriatic arthritis (IRR 1.92; 95% CI 1.65-2.23). Moreover, presence vs absence of migraine was associated with 1.88-fold higher odds of prevalent psoriasis (OR 1.88; 95% CI 1.32-3.67).
Study details: Findings are from a systematic review and meta-analysis of 10 studies including 6,745,968 participants.
Disclosures: This study did not declare the funding source. The authors declared no conflicts of interest.
Source: Huang IH et al. Bidirectional associations between psoriasis and migraine: A systematic review and meta-analysis. J Dtsch Dermatol Ges. 2023;21(5):493-502 (Apr 17). doi: 10.1111/ddg.14994
Key clinical point: This meta-analysis demonstrated a significant bidirectional association between psoriasis and migraine, with greater severity of psoriasis being associated with an increasingly higher risk of developing migraine.
Major finding: Presence vs absence of psoriasis was associated with 1.69-fold higher odds of prevalent migraine (pooled odds ratio [OR] 1.69; 95% CI 1.26-2.28), with the risk for incident migraine being significantly higher in patients with mild (incidence rate ratio [IRR] 1.37; 95% CI 1.30-1.44) and severe (IRR 1.55; 95% CI 1.29-1.86) psoriasis and psoriatic arthritis (IRR 1.92; 95% CI 1.65-2.23). Moreover, presence vs absence of migraine was associated with 1.88-fold higher odds of prevalent psoriasis (OR 1.88; 95% CI 1.32-3.67).
Study details: Findings are from a systematic review and meta-analysis of 10 studies including 6,745,968 participants.
Disclosures: This study did not declare the funding source. The authors declared no conflicts of interest.
Source: Huang IH et al. Bidirectional associations between psoriasis and migraine: A systematic review and meta-analysis. J Dtsch Dermatol Ges. 2023;21(5):493-502 (Apr 17). doi: 10.1111/ddg.14994
Key clinical point: This meta-analysis demonstrated a significant bidirectional association between psoriasis and migraine, with greater severity of psoriasis being associated with an increasingly higher risk of developing migraine.
Major finding: Presence vs absence of psoriasis was associated with 1.69-fold higher odds of prevalent migraine (pooled odds ratio [OR] 1.69; 95% CI 1.26-2.28), with the risk for incident migraine being significantly higher in patients with mild (incidence rate ratio [IRR] 1.37; 95% CI 1.30-1.44) and severe (IRR 1.55; 95% CI 1.29-1.86) psoriasis and psoriatic arthritis (IRR 1.92; 95% CI 1.65-2.23). Moreover, presence vs absence of migraine was associated with 1.88-fold higher odds of prevalent psoriasis (OR 1.88; 95% CI 1.32-3.67).
Study details: Findings are from a systematic review and meta-analysis of 10 studies including 6,745,968 participants.
Disclosures: This study did not declare the funding source. The authors declared no conflicts of interest.
Source: Huang IH et al. Bidirectional associations between psoriasis and migraine: A systematic review and meta-analysis. J Dtsch Dermatol Ges. 2023;21(5):493-502 (Apr 17). doi: 10.1111/ddg.14994