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Emmanuel Farber, MD, PhD, a renowned pathologist who made fundamental contributions to our understanding of chemical carcinogenesis, passed away on August 3 at the age of 95.
Dr Farber’s studies in experimental pathology demonstrated that chemical carcinogens are capable of binding to nucleic acids, in turn generating specific DNA adducts.
These early studies led to the observation that chemical carcinogenesis is a sequential process.
Dr Farber later proved this theory by showing that cancer could be induced through a series of step-by-step chemical treatments in the liver. He served on the Surgeon General’s first Advisory Committee on Smoking and Health from 1961 to 1964.
The committee was responsible for issuing the 1964 Surgeon General’s Report, which has now done more to prevent tobacco-related disease than any other preventive measure.
Throughout his career, Dr Farber promoted the concept that to understand carcinogenesis, one must also understand the cellular, genetic, metabolic, and molecular changes that are occurring during the process. This mindset, along with Dr Farber’s energy and enthusiasm in exploring the nature of cancer, has served as a source of inspiration and guidance for cancer researchers worldwide.
Dr Farber was born in Toronto, Canada, on October 19, 1918. He obtained his medical degree from the Faculty of Medicine, University of Toronto in 1942.
After completing his residency training in pathology at the Hamilton General Hospital in Ontario, Canada, he served in the Royal Canadian Army Medical Corps and later obtained a doctorate in biochemistry from the University of California, Berkeley.
His academic career began at Tulane University in New Orleans, Louisiana. It continued with his appointment as Professor and Chairman of Pathology and Professor of Biochemistry at the University of Pittsburgh School of Medicine and at the Fels Research Institute, Temple University School of Medicine, in Philadelphia, Pennsylvania, where he was Professor of Pathology and Biochemistry and Director of the Institute.
In 1975, Dr Farber moved back to his native city to take the post of Professor and Chairman of the Department of Pathology and Professor in the Department of Biochemistry at the University of Toronto. At his death, he held the title of Chairman Emeritus and Professor in the Department of Pathology at the University of Toronto.
Dr Farber is survived by his daughter Naomi Farber, son-in-law Steven Grosby, and grandson Samuel Grosby, who wish to extend their sincere appreciation to those who enriched his personal and professional life and joined his tireless search for scientific truth. 
Emmanuel Farber, MD, PhD, a renowned pathologist who made fundamental contributions to our understanding of chemical carcinogenesis, passed away on August 3 at the age of 95.
Dr Farber’s studies in experimental pathology demonstrated that chemical carcinogens are capable of binding to nucleic acids, in turn generating specific DNA adducts.
These early studies led to the observation that chemical carcinogenesis is a sequential process.
Dr Farber later proved this theory by showing that cancer could be induced through a series of step-by-step chemical treatments in the liver. He served on the Surgeon General’s first Advisory Committee on Smoking and Health from 1961 to 1964.
The committee was responsible for issuing the 1964 Surgeon General’s Report, which has now done more to prevent tobacco-related disease than any other preventive measure.
Throughout his career, Dr Farber promoted the concept that to understand carcinogenesis, one must also understand the cellular, genetic, metabolic, and molecular changes that are occurring during the process. This mindset, along with Dr Farber’s energy and enthusiasm in exploring the nature of cancer, has served as a source of inspiration and guidance for cancer researchers worldwide.
Dr Farber was born in Toronto, Canada, on October 19, 1918. He obtained his medical degree from the Faculty of Medicine, University of Toronto in 1942.
After completing his residency training in pathology at the Hamilton General Hospital in Ontario, Canada, he served in the Royal Canadian Army Medical Corps and later obtained a doctorate in biochemistry from the University of California, Berkeley.
His academic career began at Tulane University in New Orleans, Louisiana. It continued with his appointment as Professor and Chairman of Pathology and Professor of Biochemistry at the University of Pittsburgh School of Medicine and at the Fels Research Institute, Temple University School of Medicine, in Philadelphia, Pennsylvania, where he was Professor of Pathology and Biochemistry and Director of the Institute.
In 1975, Dr Farber moved back to his native city to take the post of Professor and Chairman of the Department of Pathology and Professor in the Department of Biochemistry at the University of Toronto. At his death, he held the title of Chairman Emeritus and Professor in the Department of Pathology at the University of Toronto.
Dr Farber is survived by his daughter Naomi Farber, son-in-law Steven Grosby, and grandson Samuel Grosby, who wish to extend their sincere appreciation to those who enriched his personal and professional life and joined his tireless search for scientific truth.
Emmanuel Farber, MD, PhD, a renowned pathologist who made fundamental contributions to our understanding of chemical carcinogenesis, passed away on August 3 at the age of 95.
Dr Farber’s studies in experimental pathology demonstrated that chemical carcinogens are capable of binding to nucleic acids, in turn generating specific DNA adducts.
These early studies led to the observation that chemical carcinogenesis is a sequential process.
Dr Farber later proved this theory by showing that cancer could be induced through a series of step-by-step chemical treatments in the liver. He served on the Surgeon General’s first Advisory Committee on Smoking and Health from 1961 to 1964.
The committee was responsible for issuing the 1964 Surgeon General’s Report, which has now done more to prevent tobacco-related disease than any other preventive measure.
Throughout his career, Dr Farber promoted the concept that to understand carcinogenesis, one must also understand the cellular, genetic, metabolic, and molecular changes that are occurring during the process. This mindset, along with Dr Farber’s energy and enthusiasm in exploring the nature of cancer, has served as a source of inspiration and guidance for cancer researchers worldwide.
Dr Farber was born in Toronto, Canada, on October 19, 1918. He obtained his medical degree from the Faculty of Medicine, University of Toronto in 1942.
After completing his residency training in pathology at the Hamilton General Hospital in Ontario, Canada, he served in the Royal Canadian Army Medical Corps and later obtained a doctorate in biochemistry from the University of California, Berkeley.
His academic career began at Tulane University in New Orleans, Louisiana. It continued with his appointment as Professor and Chairman of Pathology and Professor of Biochemistry at the University of Pittsburgh School of Medicine and at the Fels Research Institute, Temple University School of Medicine, in Philadelphia, Pennsylvania, where he was Professor of Pathology and Biochemistry and Director of the Institute.
In 1975, Dr Farber moved back to his native city to take the post of Professor and Chairman of the Department of Pathology and Professor in the Department of Biochemistry at the University of Toronto. At his death, he held the title of Chairman Emeritus and Professor in the Department of Pathology at the University of Toronto.
Dr Farber is survived by his daughter Naomi Farber, son-in-law Steven Grosby, and grandson Samuel Grosby, who wish to extend their sincere appreciation to those who enriched his personal and professional life and joined his tireless search for scientific truth.