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Key clinical point: Serum level of 25-hydroxyvitamin D (25[OH]D) was inversely associated with albuminuria as an indicator of diabetic nephropathy in patients with type 2 diabetes mellitus (T2D), with the prevalence of macroalbuminuria increasing when the serum 25(OH)D level was <20 ng/mL.

 

Major finding: A strong negative association was observed between the serum 25(OH)D level and severity of albuminuria (r, 0.257; P < .001), with the prevalence of vitamin D deficiency being 61.8%, 33.3%, and 24.0% in patients with macroalbuminuria, microalbuminuria, and normoalbuminuria, respectively.

 

Study details: This was a cross-sectional study including 200 patients with T2D, of which 100, 66, and 34 had normoalbuminuria, microalbuminuria, and macroalbuminuria, respectively.

 

Disclosures: This study was supported by Shiraz University of Medical Sciences, Iran. The authors declared no competing interests.

 

Source: Zomorodian SA et al. Assessment of the relationship between 25-hydroxyvitamin D and albuminuria in type 2 diabetes mellitus. BMC Endocr Disord. 2022;22:171 (Jul 4). Doi: 10.1186/s12902-022-01088-2

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Key clinical point: Serum level of 25-hydroxyvitamin D (25[OH]D) was inversely associated with albuminuria as an indicator of diabetic nephropathy in patients with type 2 diabetes mellitus (T2D), with the prevalence of macroalbuminuria increasing when the serum 25(OH)D level was <20 ng/mL.

 

Major finding: A strong negative association was observed between the serum 25(OH)D level and severity of albuminuria (r, 0.257; P < .001), with the prevalence of vitamin D deficiency being 61.8%, 33.3%, and 24.0% in patients with macroalbuminuria, microalbuminuria, and normoalbuminuria, respectively.

 

Study details: This was a cross-sectional study including 200 patients with T2D, of which 100, 66, and 34 had normoalbuminuria, microalbuminuria, and macroalbuminuria, respectively.

 

Disclosures: This study was supported by Shiraz University of Medical Sciences, Iran. The authors declared no competing interests.

 

Source: Zomorodian SA et al. Assessment of the relationship between 25-hydroxyvitamin D and albuminuria in type 2 diabetes mellitus. BMC Endocr Disord. 2022;22:171 (Jul 4). Doi: 10.1186/s12902-022-01088-2

Key clinical point: Serum level of 25-hydroxyvitamin D (25[OH]D) was inversely associated with albuminuria as an indicator of diabetic nephropathy in patients with type 2 diabetes mellitus (T2D), with the prevalence of macroalbuminuria increasing when the serum 25(OH)D level was <20 ng/mL.

 

Major finding: A strong negative association was observed between the serum 25(OH)D level and severity of albuminuria (r, 0.257; P < .001), with the prevalence of vitamin D deficiency being 61.8%, 33.3%, and 24.0% in patients with macroalbuminuria, microalbuminuria, and normoalbuminuria, respectively.

 

Study details: This was a cross-sectional study including 200 patients with T2D, of which 100, 66, and 34 had normoalbuminuria, microalbuminuria, and macroalbuminuria, respectively.

 

Disclosures: This study was supported by Shiraz University of Medical Sciences, Iran. The authors declared no competing interests.

 

Source: Zomorodian SA et al. Assessment of the relationship between 25-hydroxyvitamin D and albuminuria in type 2 diabetes mellitus. BMC Endocr Disord. 2022;22:171 (Jul 4). Doi: 10.1186/s12902-022-01088-2

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Clinical Edge Journal Scan: Type 2 Diabetes, August 2022
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