Deborah Sturpe, PharmD, BCPS

Transdermal progesterone cream, at the dose used in this study, did not improve menopausal symptoms compared with placebo. The study, however, might not have been large enough to detect a difference if one really exists.

In light of recent safety concerns over the use of other types of hormone replacement therapy, treatment of menopausal symptoms with transdermal progesterone should not be used unless better information supporting its benefit becomes available.

Transdermal progesterone cream, at the dose used in this study, did not improve menopausal symptoms compared with placebo. The study, however, might not have been large enough to detect a difference if one really exists.

In light of recent safety concerns over the use of other types of hormone replacement therapy, treatment of menopausal symptoms with transdermal progesterone should not be used unless better information supporting its benefit becomes available.

Transdermal progesterone cream, at the dose used in this study, did not improve menopausal symptoms compared with placebo. The study, however, might not have been large enough to detect a difference if one really exists.

In light of recent safety concerns over the use of other types of hormone replacement therapy, treatment of menopausal symptoms with transdermal progesterone should not be used unless better information supporting its benefit becomes available.