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Omitting sentinel lymph node biopsy safe for some early breast cancers
Data support “the argument that sentinel node positivity is not, in and of itself, a critical parameter that determines therapeutic plans and...
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High-risk colon polyps detected at screening colonoscopy linked to liver cancer death
“Our findings imply that risk stratification at colonoscopy might be helping to identify patients at need for liver cancer surveillance.”
Article
Artificial sweeteners in processed foods tied to increased depression risk
“Given this potential association between ultraprocessed food and multiple adverse health conditions, wherever possible individuals may wish to...
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More data needed on stopping GLP-1 use prior to endoscopy
Semaglutide, and other GLP-1 receptor agonists, could be problematic for patients undergoing endoscopy.
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AHA reviews impact of aggressive LDL lowering on the brain
The risk for hemorrhagic stroke associated with statin therapy in patients without a history of cerebrovascular disease is “small and consistently...
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Should clinic BP be routinely measured lying down?
The data revealed that 16% of those without seated hypertension had supine hypertension, while 74% of those with seated hypertension had supine...
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Blood transfusions linked to intracerebral hemorrhage risk
Patients receiving red blood cell transfusions from donors who later developed multiple spontaneous ICHs were at a significantly increased risk of...
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Patisiran (Onpattro) for ATTR cardiomyopathy gets FDA panel thumbs up
The study also met its first secondary endpoint, demonstrating a statistically significant and clinically meaningful benefit on health status and...
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Cold weather may challenge blood pressure control
In an observational study, BP control rates decreased by up to 5% during the cold winter months, compared with control rates in the warm summer...
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‘New dawn’ for aldosterone as drug target in hypertension?
The medication lowered systolic blood pressure significantly more than placebo, with the greatest effects seen in adults with obesity.
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Exercise tied to lower mortality risk across cancer types
Regular exercise can significantly reduce a cancer survivor’s mortality from cancer or other causes.
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Positive topline results for antihypertensive zilebesiran
The small-interfering RNA therapeutic met the primary and secondary endpoints with an “encouraging” safety profile.
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NAFLD raises risk for colorectal adenomatous polyps
In the fully adjusted model, NAFLD was a significant independent risk factor for adenomatous polyps but not for nonadenomatous polyps.
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New European restrictions on topiramate in pregnancy
For patients using topiramate for the treatment of epilepsy, the PRAC now recommends that the medicine not be used during pregnancy.