First-trimester tests for trisomies 21 and 18 as sensitive as triple screen

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First-trimester tests for trisomies 21 and 18 as sensitive as triple screen
PRACTICE RECOMMENDATIONS

First-trimester screening for trisomies 21 and 18 with maternal serum markers and ultra-sonographic measurement of fetal nuchal translucency is more sensitive than second-trimester “triple screen.” Application of this finding to general practice is limited by lack of access to radiologists trained in this more specialized prenatal ultrasound measurement.

 
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Practice Recommendations from Key Studies

Wapner R, Thom E, Simpson JL, et al. First-trimester screening for trisomies 21 and 18. N Engl J Med 2003; 349:1405–1413.

Peter R. Lewis, MD
Ron Pasalio, MD
Penn State University/Good Samaritan Hospital, Family & Community Medicine Residency Program, Lebanon, Pa. E-mail: [email protected].

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The Journal of Family Practice - 53(3)
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172-188
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Author and Disclosure Information

Practice Recommendations from Key Studies

Wapner R, Thom E, Simpson JL, et al. First-trimester screening for trisomies 21 and 18. N Engl J Med 2003; 349:1405–1413.

Peter R. Lewis, MD
Ron Pasalio, MD
Penn State University/Good Samaritan Hospital, Family & Community Medicine Residency Program, Lebanon, Pa. E-mail: [email protected].

Author and Disclosure Information

Practice Recommendations from Key Studies

Wapner R, Thom E, Simpson JL, et al. First-trimester screening for trisomies 21 and 18. N Engl J Med 2003; 349:1405–1413.

Peter R. Lewis, MD
Ron Pasalio, MD
Penn State University/Good Samaritan Hospital, Family & Community Medicine Residency Program, Lebanon, Pa. E-mail: [email protected].

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PRACTICE RECOMMENDATIONS

First-trimester screening for trisomies 21 and 18 with maternal serum markers and ultra-sonographic measurement of fetal nuchal translucency is more sensitive than second-trimester “triple screen.” Application of this finding to general practice is limited by lack of access to radiologists trained in this more specialized prenatal ultrasound measurement.

 
PRACTICE RECOMMENDATIONS

First-trimester screening for trisomies 21 and 18 with maternal serum markers and ultra-sonographic measurement of fetal nuchal translucency is more sensitive than second-trimester “triple screen.” Application of this finding to general practice is limited by lack of access to radiologists trained in this more specialized prenatal ultrasound measurement.

 
Issue
The Journal of Family Practice - 53(3)
Issue
The Journal of Family Practice - 53(3)
Page Number
172-188
Page Number
172-188
Publications
Publications
Topics
Article Type
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First-trimester tests for trisomies 21 and 18 as sensitive as triple screen
Display Headline
First-trimester tests for trisomies 21 and 18 as sensitive as triple screen
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