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Candesartan reduces cardiovascular death in CHF patients on ACE inhibitor
PRACTICE RECOMMENDATIONS

The addition of candesartan (Atacand) to an angiotensin-converting enzyme (ACE) inhibitor and other treatment reduces cardiovascular death and hospital admissions of patients with congestive heart failure (CHF). As in studies conducted with valsartan (Diovan), candesartan added to an ACE inhibitor does not decrease overall mortality. Clinicians should add candesartan to the medical regimen in nonallergic CHF patients with an ejection fraction of 40% or lower who are already on an optimal dose of an ACE inhibitor.

 
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Practice Recommendations from Key Studies

McMurray JJV, Östergren J, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003; 362:767–771.

Ginger Wiley, MD
Charles Cole, MD
Department of Family Practice, University of Virginia Health Sciences Center, Stoney Creek Family Practice, Nellysford, Va. E-mail: [email protected].

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The Journal of Family Practice - 53(2)
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93-105
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Practice Recommendations from Key Studies

McMurray JJV, Östergren J, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003; 362:767–771.

Ginger Wiley, MD
Charles Cole, MD
Department of Family Practice, University of Virginia Health Sciences Center, Stoney Creek Family Practice, Nellysford, Va. E-mail: [email protected].

Author and Disclosure Information

Practice Recommendations from Key Studies

McMurray JJV, Östergren J, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003; 362:767–771.

Ginger Wiley, MD
Charles Cole, MD
Department of Family Practice, University of Virginia Health Sciences Center, Stoney Creek Family Practice, Nellysford, Va. E-mail: [email protected].

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PRACTICE RECOMMENDATIONS

The addition of candesartan (Atacand) to an angiotensin-converting enzyme (ACE) inhibitor and other treatment reduces cardiovascular death and hospital admissions of patients with congestive heart failure (CHF). As in studies conducted with valsartan (Diovan), candesartan added to an ACE inhibitor does not decrease overall mortality. Clinicians should add candesartan to the medical regimen in nonallergic CHF patients with an ejection fraction of 40% or lower who are already on an optimal dose of an ACE inhibitor.

 
PRACTICE RECOMMENDATIONS

The addition of candesartan (Atacand) to an angiotensin-converting enzyme (ACE) inhibitor and other treatment reduces cardiovascular death and hospital admissions of patients with congestive heart failure (CHF). As in studies conducted with valsartan (Diovan), candesartan added to an ACE inhibitor does not decrease overall mortality. Clinicians should add candesartan to the medical regimen in nonallergic CHF patients with an ejection fraction of 40% or lower who are already on an optimal dose of an ACE inhibitor.

 
Issue
The Journal of Family Practice - 53(2)
Issue
The Journal of Family Practice - 53(2)
Page Number
93-105
Page Number
93-105
Publications
Publications
Topics
Article Type
Display Headline
Candesartan reduces cardiovascular death in CHF patients on ACE inhibitor
Display Headline
Candesartan reduces cardiovascular death in CHF patients on ACE inhibitor
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