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Key clinical point: Management of colorectal cancer (CRC) and synchronous liver metastases with staged liver-first or bowel-first routes or synchronous combined liver and bowel surgery, all with contemporary systemic chemotherapy, led to similar perioperative complications and oncological outcomes.
Major finding: Postoperative complications (P = .66), total critical care occupancy (P = .92) and mean total inpatient stay (P = .91) were similar between synchronous and staged management pathways. Overall, 35% of patients were disease-free at 12 months, with no difference between groups (P = .448).
Study details: Findings are from CoSMIC, a prospective inception cohort study including 125 patients with CRC and synchronous liver metastases.
Disclosures: AKC Chan was supported by a grant from the Dickinson Trust.
Source: Chan AKC et al. Ann Surg Oncol. 2021 Oct 30. doi: 10.1245/s10434-021-11017-7.
Key clinical point: Management of colorectal cancer (CRC) and synchronous liver metastases with staged liver-first or bowel-first routes or synchronous combined liver and bowel surgery, all with contemporary systemic chemotherapy, led to similar perioperative complications and oncological outcomes.
Major finding: Postoperative complications (P = .66), total critical care occupancy (P = .92) and mean total inpatient stay (P = .91) were similar between synchronous and staged management pathways. Overall, 35% of patients were disease-free at 12 months, with no difference between groups (P = .448).
Study details: Findings are from CoSMIC, a prospective inception cohort study including 125 patients with CRC and synchronous liver metastases.
Disclosures: AKC Chan was supported by a grant from the Dickinson Trust.
Source: Chan AKC et al. Ann Surg Oncol. 2021 Oct 30. doi: 10.1245/s10434-021-11017-7.
Key clinical point: Management of colorectal cancer (CRC) and synchronous liver metastases with staged liver-first or bowel-first routes or synchronous combined liver and bowel surgery, all with contemporary systemic chemotherapy, led to similar perioperative complications and oncological outcomes.
Major finding: Postoperative complications (P = .66), total critical care occupancy (P = .92) and mean total inpatient stay (P = .91) were similar between synchronous and staged management pathways. Overall, 35% of patients were disease-free at 12 months, with no difference between groups (P = .448).
Study details: Findings are from CoSMIC, a prospective inception cohort study including 125 patients with CRC and synchronous liver metastases.
Disclosures: AKC Chan was supported by a grant from the Dickinson Trust.
Source: Chan AKC et al. Ann Surg Oncol. 2021 Oct 30. doi: 10.1245/s10434-021-11017-7.