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Key clinical point: Computer-aided detection (CADe) has higher rates of colorectal neoplasia detection than other advanced endoscopic techniques like chromoendoscopy or mucosal visualization tools.

Major finding: The magnitude of increase in adenoma detection rate was higher with CADe vs chromoendoscopy (odds ratio [OR], 1.45; 95% confidence interval [CI], 1.14-1.85) or with increased mucosal visualization systems (OR, 1.54; 95% CI, 1.22-1.94). Compared with high-definition white-light endoscopy, only CADe showed a significant increase in the detection of large adenomas (OR, 1.69; 95% CI, 1.10-2.60).

Study details: Findings are from a systematic review and meta-analysis of 50 randomized control trials including 34,445 participants who underwent colonoscopy.

Disclosures: There was no source of funding for this study. Some of the authors declared receiving consulting fees from Olympus, Medtronic, Fuji, Boston, Aries Pharmaceutical, Braintree Laboratories, Norgine, Endokey, and GI Supply.

Source: Spadaccini M et al. Lancet Gastroenterol Hepatol. 2021 Aug 4. doi: 10.1016/S2468-1253(21)00215-6.  

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Key clinical point: Computer-aided detection (CADe) has higher rates of colorectal neoplasia detection than other advanced endoscopic techniques like chromoendoscopy or mucosal visualization tools.

Major finding: The magnitude of increase in adenoma detection rate was higher with CADe vs chromoendoscopy (odds ratio [OR], 1.45; 95% confidence interval [CI], 1.14-1.85) or with increased mucosal visualization systems (OR, 1.54; 95% CI, 1.22-1.94). Compared with high-definition white-light endoscopy, only CADe showed a significant increase in the detection of large adenomas (OR, 1.69; 95% CI, 1.10-2.60).

Study details: Findings are from a systematic review and meta-analysis of 50 randomized control trials including 34,445 participants who underwent colonoscopy.

Disclosures: There was no source of funding for this study. Some of the authors declared receiving consulting fees from Olympus, Medtronic, Fuji, Boston, Aries Pharmaceutical, Braintree Laboratories, Norgine, Endokey, and GI Supply.

Source: Spadaccini M et al. Lancet Gastroenterol Hepatol. 2021 Aug 4. doi: 10.1016/S2468-1253(21)00215-6.  

Key clinical point: Computer-aided detection (CADe) has higher rates of colorectal neoplasia detection than other advanced endoscopic techniques like chromoendoscopy or mucosal visualization tools.

Major finding: The magnitude of increase in adenoma detection rate was higher with CADe vs chromoendoscopy (odds ratio [OR], 1.45; 95% confidence interval [CI], 1.14-1.85) or with increased mucosal visualization systems (OR, 1.54; 95% CI, 1.22-1.94). Compared with high-definition white-light endoscopy, only CADe showed a significant increase in the detection of large adenomas (OR, 1.69; 95% CI, 1.10-2.60).

Study details: Findings are from a systematic review and meta-analysis of 50 randomized control trials including 34,445 participants who underwent colonoscopy.

Disclosures: There was no source of funding for this study. Some of the authors declared receiving consulting fees from Olympus, Medtronic, Fuji, Boston, Aries Pharmaceutical, Braintree Laboratories, Norgine, Endokey, and GI Supply.

Source: Spadaccini M et al. Lancet Gastroenterol Hepatol. 2021 Aug 4. doi: 10.1016/S2468-1253(21)00215-6.  

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