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Diclofenac more effective than acetaminophen in osteoarthritis of the knee
Author(s)
Marc R. Via, MD
PRACTICE RECOMMENDATIONS

Diclofenac 150 mg/d is more effective in controlling osteoarthritis symptoms than acetaminophen 4 g/d in patients previously requiring an nonsteroidal anti-inflammatory drug (NSAID).

Since acetaminophen is less expensive and better tolerated, it is reasonable to attempt a 2-week trial in all patients prior to initiating treatment with NSAIDs.

 
Article PDF
5207JFP_POEMs1.pdf
Author and Disclosure Information

Practice Recommendations from Key Studies

Case JP, Baliumnas AJ, Block JA. Lack of efficacy of acetaminophen in treating symptomatic knee osteoarthritis. A randomized, double-blind, placebo-controlled comparison trial with diclofenac sodium. Arch Intern Med 2003; 163:169–178.

Marc R. Via, MD
Department of Family and Community Medicine, Scott & White Memorial Hospital, Texas A & M University System Health Science Center College of Medicine Temple, Tex.

[email protected].

Issue
The Journal of Family Practice - 52(7)
Publications
The Journal of Family Practice
MDedge Family Medicine
Topics
Pain
Page Number
512-525
Sections
Q&A
Author(s)
Marc R. Via, MD
Author(s)
Marc R. Via, MD
Author and Disclosure Information

Practice Recommendations from Key Studies

Case JP, Baliumnas AJ, Block JA. Lack of efficacy of acetaminophen in treating symptomatic knee osteoarthritis. A randomized, double-blind, placebo-controlled comparison trial with diclofenac sodium. Arch Intern Med 2003; 163:169–178.

Marc R. Via, MD
Department of Family and Community Medicine, Scott & White Memorial Hospital, Texas A & M University System Health Science Center College of Medicine Temple, Tex.

[email protected].

Author and Disclosure Information

Practice Recommendations from Key Studies

Case JP, Baliumnas AJ, Block JA. Lack of efficacy of acetaminophen in treating symptomatic knee osteoarthritis. A randomized, double-blind, placebo-controlled comparison trial with diclofenac sodium. Arch Intern Med 2003; 163:169–178.

Marc R. Via, MD
Department of Family and Community Medicine, Scott & White Memorial Hospital, Texas A & M University System Health Science Center College of Medicine Temple, Tex.

[email protected].

Article PDF
5207JFP_POEMs1.pdf
Article PDF
5207JFP_POEMs1.pdf
PRACTICE RECOMMENDATIONS

Diclofenac 150 mg/d is more effective in controlling osteoarthritis symptoms than acetaminophen 4 g/d in patients previously requiring an nonsteroidal anti-inflammatory drug (NSAID).

Since acetaminophen is less expensive and better tolerated, it is reasonable to attempt a 2-week trial in all patients prior to initiating treatment with NSAIDs.

 
PRACTICE RECOMMENDATIONS

Diclofenac 150 mg/d is more effective in controlling osteoarthritis symptoms than acetaminophen 4 g/d in patients previously requiring an nonsteroidal anti-inflammatory drug (NSAID).

Since acetaminophen is less expensive and better tolerated, it is reasonable to attempt a 2-week trial in all patients prior to initiating treatment with NSAIDs.

 
Issue
The Journal of Family Practice - 52(7)
Issue
The Journal of Family Practice - 52(7)
Page Number
512-525
Page Number
512-525
Publications
The Journal of Family Practice
MDedge Family Medicine
Publications
The Journal of Family Practice
MDedge Family Medicine
Topics
Pain
Article Type
Article
Display Headline
Diclofenac more effective than acetaminophen in osteoarthritis of the knee
Display Headline
Diclofenac more effective than acetaminophen in osteoarthritis of the knee
Sections
Q&A
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