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Ephedra and ephedrine: Modest short-term weight loss, with a price
PRACTICE RECOMMENDATIONS

Products containing ephedrine and ephedra promote a 0.6–1.0 kg/mo weight loss over 2 to 6 months. However, the impact of these products on long-term weight loss or athletic performance is uncertain. Their use is associated with a 2- to 3-fold higher rate of psychiatric symptoms, autonomic hyperactivity, upper gastrointestinal symptoms, and heart palpitations. Several serious adverse events—such as death, myocardial infarction, and stroke—have been reported, with a rate estimated at <0.1%.

 
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Practice Recommendations from Key Studies

Shekelle PG, Hardy ML, Morton SC et al. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance. A meta-analysis. JAMA 2003; 289:1537–1545.

Cari Worley, MD
Erik Lindbloom, MD, MSPH
Department of Family and Community Medicine, University of Missouri–Columbia.

[email protected].

Issue
The Journal of Family Practice - 52(7)
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Page Number
512-525
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Author and Disclosure Information

Practice Recommendations from Key Studies

Shekelle PG, Hardy ML, Morton SC et al. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance. A meta-analysis. JAMA 2003; 289:1537–1545.

Cari Worley, MD
Erik Lindbloom, MD, MSPH
Department of Family and Community Medicine, University of Missouri–Columbia.

[email protected].

Author and Disclosure Information

Practice Recommendations from Key Studies

Shekelle PG, Hardy ML, Morton SC et al. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance. A meta-analysis. JAMA 2003; 289:1537–1545.

Cari Worley, MD
Erik Lindbloom, MD, MSPH
Department of Family and Community Medicine, University of Missouri–Columbia.

[email protected].

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PRACTICE RECOMMENDATIONS

Products containing ephedrine and ephedra promote a 0.6–1.0 kg/mo weight loss over 2 to 6 months. However, the impact of these products on long-term weight loss or athletic performance is uncertain. Their use is associated with a 2- to 3-fold higher rate of psychiatric symptoms, autonomic hyperactivity, upper gastrointestinal symptoms, and heart palpitations. Several serious adverse events—such as death, myocardial infarction, and stroke—have been reported, with a rate estimated at <0.1%.

 
PRACTICE RECOMMENDATIONS

Products containing ephedrine and ephedra promote a 0.6–1.0 kg/mo weight loss over 2 to 6 months. However, the impact of these products on long-term weight loss or athletic performance is uncertain. Their use is associated with a 2- to 3-fold higher rate of psychiatric symptoms, autonomic hyperactivity, upper gastrointestinal symptoms, and heart palpitations. Several serious adverse events—such as death, myocardial infarction, and stroke—have been reported, with a rate estimated at <0.1%.

 
Issue
The Journal of Family Practice - 52(7)
Issue
The Journal of Family Practice - 52(7)
Page Number
512-525
Page Number
512-525
Publications
Publications
Topics
Article Type
Display Headline
Ephedra and ephedrine: Modest short-term weight loss, with a price
Display Headline
Ephedra and ephedrine: Modest short-term weight loss, with a price
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