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Estrogen plus progestin does not decrease— and may actually increase—the incidence of dementia, mild cognitive impairment, and cognitive dysfunction in elderly postmenopausal women. The effect of unopposed estrogen on these outcomes is still unknown. With these new findings and the recently reported results of the Women’s Health Initiative, for most women the benefits of estrogen plus progestin do not outweigh the risks.
Estrogen plus progestin does not decrease— and may actually increase—the incidence of dementia, mild cognitive impairment, and cognitive dysfunction in elderly postmenopausal women. The effect of unopposed estrogen on these outcomes is still unknown. With these new findings and the recently reported results of the Women’s Health Initiative, for most women the benefits of estrogen plus progestin do not outweigh the risks.
Estrogen plus progestin does not decrease— and may actually increase—the incidence of dementia, mild cognitive impairment, and cognitive dysfunction in elderly postmenopausal women. The effect of unopposed estrogen on these outcomes is still unknown. With these new findings and the recently reported results of the Women’s Health Initiative, for most women the benefits of estrogen plus progestin do not outweigh the risks.