Exocrine pancreatic function is preserved during the first week of critical illness in children

Key clinical point: Exocrine pancreatic function appeared normal in critically ill children during the first week of admission to the pediatric intensive care unit (PICU).

Major finding: Fecal elastase-1 concentrations were normal (1-2 μg/g; n=10). Mean amylase levels on admission and PICU discharge were 13 (interquartile range [IQR], 6.5-41.5) U/L and 15.5 (IQR, 7-44) U/L, respectively. Mean lipase levels on admission and at PICU discharge were 11 (IQR, 6.8-19.5) U/L and 16.5 (IQR, 12.3-36.8) U/L, respectively.

Study details: Findings are from a prospective observational study that included 15 critically ill children (median age, 5 months) admitted to PICU (median stay, 15 days) at a tertiary hospital in Madrid, Spain.

Disclosures: No specific funding source was identified. The authors did not report any disclosures.

Source: Solana Garcia MJ et al. Pedia Crit Care Med. 2021 Mar doi: 10.1097/01.pcc.0000738960.34833.ce.

Key clinical point: Exocrine pancreatic function appeared normal in critically ill children during the first week of admission to the pediatric intensive care unit (PICU).

Major finding: Fecal elastase-1 concentrations were normal (1-2 μg/g; n=10). Mean amylase levels on admission and PICU discharge were 13 (interquartile range [IQR], 6.5-41.5) U/L and 15.5 (IQR, 7-44) U/L, respectively. Mean lipase levels on admission and at PICU discharge were 11 (IQR, 6.8-19.5) U/L and 16.5 (IQR, 12.3-36.8) U/L, respectively.

Study details: Findings are from a prospective observational study that included 15 critically ill children (median age, 5 months) admitted to PICU (median stay, 15 days) at a tertiary hospital in Madrid, Spain.

Disclosures: No specific funding source was identified. The authors did not report any disclosures.

Source: Solana Garcia MJ et al. Pedia Crit Care Med. 2021 Mar doi: 10.1097/01.pcc.0000738960.34833.ce.

Key clinical point: Exocrine pancreatic function appeared normal in critically ill children during the first week of admission to the pediatric intensive care unit (PICU).

Major finding: Fecal elastase-1 concentrations were normal (1-2 μg/g; n=10). Mean amylase levels on admission and PICU discharge were 13 (interquartile range [IQR], 6.5-41.5) U/L and 15.5 (IQR, 7-44) U/L, respectively. Mean lipase levels on admission and at PICU discharge were 11 (IQR, 6.8-19.5) U/L and 16.5 (IQR, 12.3-36.8) U/L, respectively.

Study details: Findings are from a prospective observational study that included 15 critically ill children (median age, 5 months) admitted to PICU (median stay, 15 days) at a tertiary hospital in Madrid, Spain.

Disclosures: No specific funding source was identified. The authors did not report any disclosures.

Source: Solana Garcia MJ et al. Pedia Crit Care Med. 2021 Mar doi: 10.1097/01.pcc.0000738960.34833.ce.