Article Type
Article
Changed
Tue, 10/29/2024 - 12:22
Display Headline
Lung Cancer Screening: A Need for Adjunctive Testing
Author(s)
Eric S. Edell, MD, FCCP

Click to read more from Pulmonology Data Trends 2023.

References
  1. Naidch DP et al. Radiology. 1990;175(3):729-731. doi:10.1148/radiology.175.3.2343122
  2. Kaneko M et al. Radiology. 1996;201(3):798-802. doi:10.1148/radiology.201.3.8939234
  3. National Lung Screening Trial Research Team. Radiology. 2011;258(1):243-253. doi:10.1148/radiol.10091808
  4. National Lung Screening Trial Research Team. J Thorac Oncol. 2019;14(10):1732-1742. doi:10.1016/j.jtho.2019.05.044
  5. Mazzone PJ et al. Chest. 2021;160(5):e427-e494. doi:10.1016/j.chest.2021.06.063
  6. Tanner NT et al. Chest. 2023;S0012-3692(23)00175-7. doi:10.1016/j.chest.2023.02.003
  7. National Lung Screening Trial Research Team. N Engl J Med. 2011;365(5):395- 409. doi:10.1056/NEJMoa1102873
  8. Marmor HN et al. Curr Chall Thorac Surg. 2023;5:5. doi:10.21037/ccts-20-171
Author and Disclosure Information

Eric S. Edell, MD, FCCP
Internist and Pulmonologist
Mayo Clinic
Rochester, MN

Publications
MDedge Internal Medicine
CHEST Physician
Topics
Lung Cancer
Author(s)
Eric S. Edell, MD, FCCP
Author(s)
Eric S. Edell, MD, FCCP
Author and Disclosure Information

Eric S. Edell, MD, FCCP
Internist and Pulmonologist
Mayo Clinic
Rochester, MN

Author and Disclosure Information

Eric S. Edell, MD, FCCP
Internist and Pulmonologist
Mayo Clinic
Rochester, MN

Click to read more from Pulmonology Data Trends 2023.

Click to read more from Pulmonology Data Trends 2023.

References
  1. Naidch DP et al. Radiology. 1990;175(3):729-731. doi:10.1148/radiology.175.3.2343122
  2. Kaneko M et al. Radiology. 1996;201(3):798-802. doi:10.1148/radiology.201.3.8939234
  3. National Lung Screening Trial Research Team. Radiology. 2011;258(1):243-253. doi:10.1148/radiol.10091808
  4. National Lung Screening Trial Research Team. J Thorac Oncol. 2019;14(10):1732-1742. doi:10.1016/j.jtho.2019.05.044
  5. Mazzone PJ et al. Chest. 2021;160(5):e427-e494. doi:10.1016/j.chest.2021.06.063
  6. Tanner NT et al. Chest. 2023;S0012-3692(23)00175-7. doi:10.1016/j.chest.2023.02.003
  7. National Lung Screening Trial Research Team. N Engl J Med. 2011;365(5):395- 409. doi:10.1056/NEJMoa1102873
  8. Marmor HN et al. Curr Chall Thorac Surg. 2023;5:5. doi:10.21037/ccts-20-171
References
  1. Naidch DP et al. Radiology. 1990;175(3):729-731. doi:10.1148/radiology.175.3.2343122
  2. Kaneko M et al. Radiology. 1996;201(3):798-802. doi:10.1148/radiology.201.3.8939234
  3. National Lung Screening Trial Research Team. Radiology. 2011;258(1):243-253. doi:10.1148/radiol.10091808
  4. National Lung Screening Trial Research Team. J Thorac Oncol. 2019;14(10):1732-1742. doi:10.1016/j.jtho.2019.05.044
  5. Mazzone PJ et al. Chest. 2021;160(5):e427-e494. doi:10.1016/j.chest.2021.06.063
  6. Tanner NT et al. Chest. 2023;S0012-3692(23)00175-7. doi:10.1016/j.chest.2023.02.003
  7. National Lung Screening Trial Research Team. N Engl J Med. 2011;365(5):395- 409. doi:10.1056/NEJMoa1102873
  8. Marmor HN et al. Curr Chall Thorac Surg. 2023;5:5. doi:10.21037/ccts-20-171
Publications
MDedge Internal Medicine
CHEST Physician
Publications
MDedge Internal Medicine
CHEST Physician
Topics
Lung Cancer
Article Type
Article
Display Headline
Lung Cancer Screening: A Need for Adjunctive Testing
Display Headline
Lung Cancer Screening: A Need for Adjunctive Testing
Disallow All Ads
Content Gating
Open Access (article Unlocked/Open Access)
Alternative CME
Disqus Comments
Default
Eyebrow Default
Slideshow
Gate On Date
Thu, 09/21/2023 - 10:00
Un-Gate On Date
Thu, 09/21/2023 - 10:00
Use ProPublica
CFC Schedule Remove Status
Thu, 09/21/2023 - 10:00
Hide sidebar & use full width
Do not render the right sidebar.
Conference Recap Checkbox
Not Conference Recap
Clinical Edge
Display the Slideshow in this Article
Article Slideshow Optional Introduction

Slideshow below.

Early detection of lung cancer by screening with low dose computed tomography (LDCT) scanning has long been investigated as a potential means of reducing related deaths.1,2 The 2011 National Lung Screening Trial (NLST) compared LDCT scanning with standard chest radiograph (CXR). Results showed a significant reduction in mortality in high-risk current and former smokers who were screened annually (3×) with LDCT scan vs CXR.3

LDCT scanning for lung cancer is currently a standard of care, partially due to the results of the NLST.4,5 In 2013, LDCT scanning was recommended by the US Preventive Services Task Force (USPSTF), making about 8 million Americans eligible for screening.6 In 2019, an extended NLST cohort follow-up study showed that earlier detection with LDCT scanning not only delayed lung cancer death, but also prevented it—or at least delayed it by a decade or more.4,7 This sparked another change in eligibility criteria in the 2021 USPSTF guidelines, allowing an additional 6.5 million people to be eligible for screening.6

Unfortunately, LDCT scanning has some negative aspects to its use, such as high false-positive rates, repeated radiation exposure, and the lack of ability to distinguish between nodules that are benign or malignant.8 There is a need for adjunctive testing for screening. Some current research is focusing on the development of liquid biomarkers intended to be complementary to imaging as a method of using noninvasive lung cancer diagnostics.

Slide
Medscape Article
Display survey writer
Reuters content
Disable Inline Native ads
WebMD Article
Slide Media