Point shear wave elastography may help early detection of EPI in pediatric cystic fibrosis

Key clinical point: Investigation of pancreatic elasticity and exocrine pancreatic insufficiency (EPI) using point shear wave elastography (pSWE) may provide a simple, inexpensive, and noninvasive tool for early detection of EPI, thereby influencing long-term outcomes in young patients with cystic fibrosis (CF).

Major finding: The mean pSWE was significantly lower in children with CF vs healthy children (0.97±0.16 vs 1.12±0.16; P < .001). Higher disease duration was independently associated with low pSWE (R²=0.634; P < .001).

Study details: Findings are from a prospective assessment of 55 pediatric patients with CF and 60 healthy children without any chronic diseases.

Disclosures: No source of funding was identified. The authors declared no conflict of interests.

Source: Yılmaz K et al. Pediatr Int. 2021 Aug 13. doi: 10.1111/ped.14951.

Key clinical point: Investigation of pancreatic elasticity and exocrine pancreatic insufficiency (EPI) using point shear wave elastography (pSWE) may provide a simple, inexpensive, and noninvasive tool for early detection of EPI, thereby influencing long-term outcomes in young patients with cystic fibrosis (CF).

Major finding: The mean pSWE was significantly lower in children with CF vs healthy children (0.97±0.16 vs 1.12±0.16; P < .001). Higher disease duration was independently associated with low pSWE (R²=0.634; P < .001).

Study details: Findings are from a prospective assessment of 55 pediatric patients with CF and 60 healthy children without any chronic diseases.

Disclosures: No source of funding was identified. The authors declared no conflict of interests.

Source: Yılmaz K et al. Pediatr Int. 2021 Aug 13. doi: 10.1111/ped.14951.

Key clinical point: Investigation of pancreatic elasticity and exocrine pancreatic insufficiency (EPI) using point shear wave elastography (pSWE) may provide a simple, inexpensive, and noninvasive tool for early detection of EPI, thereby influencing long-term outcomes in young patients with cystic fibrosis (CF).

Major finding: The mean pSWE was significantly lower in children with CF vs healthy children (0.97±0.16 vs 1.12±0.16; P < .001). Higher disease duration was independently associated with low pSWE (R²=0.634; P < .001).

Study details: Findings are from a prospective assessment of 55 pediatric patients with CF and 60 healthy children without any chronic diseases.

Disclosures: No source of funding was identified. The authors declared no conflict of interests.

Source: Yılmaz K et al. Pediatr Int. 2021 Aug 13. doi: 10.1111/ped.14951.