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Key clinical point: Gastrectomy significantly improves survival in older patients with resectable gastric cancer. Renal disease is an independent risk predictor for poorer survival in patients who undergo surgery.
Major finding: In propensity-matched analysis (n = 44), the 3-year overall survival (OS) was significantly longer in the radical surgery vs conservative therapy group (59.4% vs 15.9%, P < .01). No surgery was independently associated with worse OS in the entire cohort (hazard ratio [HR] 3.70; P = .0001). In the surgery group, renal disease was an independent risk factor for poorer OS (HR 2.51; P < .05).
Study details: This was a retrospective observational study of patients aged ≥75 years with clinically resectable primary gastric cancer who underwent radical surgery (n = 115) or received conservative therapy (n = 33).
Disclosures: No funding source was identified for this study. The authors declared no competing interests.
Source: Ito S et al. Survival benefits of gastrectomy compared to conservative observation for older patients with resectable gastric cancer: A propensity score matched analysis. Langenbecks Arch Surg. 2022 (Apr 29). Doi: 10.1007/s00423-022-02511-x
Key clinical point: Gastrectomy significantly improves survival in older patients with resectable gastric cancer. Renal disease is an independent risk predictor for poorer survival in patients who undergo surgery.
Major finding: In propensity-matched analysis (n = 44), the 3-year overall survival (OS) was significantly longer in the radical surgery vs conservative therapy group (59.4% vs 15.9%, P < .01). No surgery was independently associated with worse OS in the entire cohort (hazard ratio [HR] 3.70; P = .0001). In the surgery group, renal disease was an independent risk factor for poorer OS (HR 2.51; P < .05).
Study details: This was a retrospective observational study of patients aged ≥75 years with clinically resectable primary gastric cancer who underwent radical surgery (n = 115) or received conservative therapy (n = 33).
Disclosures: No funding source was identified for this study. The authors declared no competing interests.
Source: Ito S et al. Survival benefits of gastrectomy compared to conservative observation for older patients with resectable gastric cancer: A propensity score matched analysis. Langenbecks Arch Surg. 2022 (Apr 29). Doi: 10.1007/s00423-022-02511-x
Key clinical point: Gastrectomy significantly improves survival in older patients with resectable gastric cancer. Renal disease is an independent risk predictor for poorer survival in patients who undergo surgery.
Major finding: In propensity-matched analysis (n = 44), the 3-year overall survival (OS) was significantly longer in the radical surgery vs conservative therapy group (59.4% vs 15.9%, P < .01). No surgery was independently associated with worse OS in the entire cohort (hazard ratio [HR] 3.70; P = .0001). In the surgery group, renal disease was an independent risk factor for poorer OS (HR 2.51; P < .05).
Study details: This was a retrospective observational study of patients aged ≥75 years with clinically resectable primary gastric cancer who underwent radical surgery (n = 115) or received conservative therapy (n = 33).
Disclosures: No funding source was identified for this study. The authors declared no competing interests.
Source: Ito S et al. Survival benefits of gastrectomy compared to conservative observation for older patients with resectable gastric cancer: A propensity score matched analysis. Langenbecks Arch Surg. 2022 (Apr 29). Doi: 10.1007/s00423-022-02511-x