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Key clinical point: Patients with both chronic kidney disease (CKD) and rheumatoid arthritis (RA) were at an increased risk for mortality compared with those with CKD alone, with RA having no impact on progressive renal decline.
Major finding: Presence of both CKD and RA vs. CKD alone was associated with an increased risk for all-cause mortality (adjusted hazard ratio [aHR] 1.73; 95% CI 1.27-2.35) and composite of myocardial infarction, cerebrovascular accident, heart failure, or death (aHR 1.65; 95% CI 1.27-2.15), without significantly increasing the risk for progressive renal decline.
Study details: The data come from a retrospective study including 3333 patients with CKD from the Chronic Renal Insufficiency Cohort (CRIC) study, of which 83 patients had RA and were taking a disease-modifying antirheumatic therapy.
Disclosures: CRIC study was supported by the US National Institute of Diabetes and Digestive and Kidney Diseases. No conflicts of interest were declared.
Source: Ezeanuna MN et al. Association of rheumatoid arthritis with mortality in chronic kidney disease: a cohort study. Clin Rheumatol. 2022 (May 25). Doi: 10.1007/s10067-022-06223-x
Key clinical point: Patients with both chronic kidney disease (CKD) and rheumatoid arthritis (RA) were at an increased risk for mortality compared with those with CKD alone, with RA having no impact on progressive renal decline.
Major finding: Presence of both CKD and RA vs. CKD alone was associated with an increased risk for all-cause mortality (adjusted hazard ratio [aHR] 1.73; 95% CI 1.27-2.35) and composite of myocardial infarction, cerebrovascular accident, heart failure, or death (aHR 1.65; 95% CI 1.27-2.15), without significantly increasing the risk for progressive renal decline.
Study details: The data come from a retrospective study including 3333 patients with CKD from the Chronic Renal Insufficiency Cohort (CRIC) study, of which 83 patients had RA and were taking a disease-modifying antirheumatic therapy.
Disclosures: CRIC study was supported by the US National Institute of Diabetes and Digestive and Kidney Diseases. No conflicts of interest were declared.
Source: Ezeanuna MN et al. Association of rheumatoid arthritis with mortality in chronic kidney disease: a cohort study. Clin Rheumatol. 2022 (May 25). Doi: 10.1007/s10067-022-06223-x
Key clinical point: Patients with both chronic kidney disease (CKD) and rheumatoid arthritis (RA) were at an increased risk for mortality compared with those with CKD alone, with RA having no impact on progressive renal decline.
Major finding: Presence of both CKD and RA vs. CKD alone was associated with an increased risk for all-cause mortality (adjusted hazard ratio [aHR] 1.73; 95% CI 1.27-2.35) and composite of myocardial infarction, cerebrovascular accident, heart failure, or death (aHR 1.65; 95% CI 1.27-2.15), without significantly increasing the risk for progressive renal decline.
Study details: The data come from a retrospective study including 3333 patients with CKD from the Chronic Renal Insufficiency Cohort (CRIC) study, of which 83 patients had RA and were taking a disease-modifying antirheumatic therapy.
Disclosures: CRIC study was supported by the US National Institute of Diabetes and Digestive and Kidney Diseases. No conflicts of interest were declared.
Source: Ezeanuna MN et al. Association of rheumatoid arthritis with mortality in chronic kidney disease: a cohort study. Clin Rheumatol. 2022 (May 25). Doi: 10.1007/s10067-022-06223-x