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Vitamin E not helpful, perhaps harmful
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Vitamin E supplementation does not decrease all-cause mortality in patients with or without pre-existing heart disease. At higher doses it can actually be harmful, although the deleterious effect is small (number needed to harm [NNH]=250). (level of evidence [LOE]=1b)

 
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Practice Recommendations from Key Studies

Miller ER 3rd, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 2005; 142:37–46.

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The Journal of Family Practice - 54(3)
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199-206
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Practice Recommendations from Key Studies

Miller ER 3rd, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 2005; 142:37–46.

Author and Disclosure Information

Practice Recommendations from Key Studies

Miller ER 3rd, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 2005; 142:37–46.

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BOTTOM LINE

Vitamin E supplementation does not decrease all-cause mortality in patients with or without pre-existing heart disease. At higher doses it can actually be harmful, although the deleterious effect is small (number needed to harm [NNH]=250). (level of evidence [LOE]=1b)

 
BOTTOM LINE

Vitamin E supplementation does not decrease all-cause mortality in patients with or without pre-existing heart disease. At higher doses it can actually be harmful, although the deleterious effect is small (number needed to harm [NNH]=250). (level of evidence [LOE]=1b)

 
Issue
The Journal of Family Practice - 54(3)
Issue
The Journal of Family Practice - 54(3)
Page Number
199-206
Page Number
199-206
Publications
Publications
Topics
Article Type
Display Headline
Vitamin E not helpful, perhaps harmful
Display Headline
Vitamin E not helpful, perhaps harmful
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