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Among arthritis patients with a recent history of bleeding ulcer, celecoxib was just as likely as diclofenac plus omeprazole to cause recurrent bleeding. The effectiveness of these two regimens in preventing recurrent bleeding compared with a general nonsteroidal antiinflammatory drug (NSAID) used alone cannot be determined from this study. Unfortunately, adverse renal effects were common with both regimens.
Among arthritis patients with a recent history of bleeding ulcer, celecoxib was just as likely as diclofenac plus omeprazole to cause recurrent bleeding. The effectiveness of these two regimens in preventing recurrent bleeding compared with a general nonsteroidal antiinflammatory drug (NSAID) used alone cannot be determined from this study. Unfortunately, adverse renal effects were common with both regimens.
Among arthritis patients with a recent history of bleeding ulcer, celecoxib was just as likely as diclofenac plus omeprazole to cause recurrent bleeding. The effectiveness of these two regimens in preventing recurrent bleeding compared with a general nonsteroidal antiinflammatory drug (NSAID) used alone cannot be determined from this study. Unfortunately, adverse renal effects were common with both regimens.