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FDA approves first-in-class inclisiran to lower LDL-C
Injectable Inclisiran (Leqvio) is now indicated as an adjunct to maximal statins in adults with cardiovascular disease and patients with...
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AHA challenges diet doctor’s study alleging COVID vax risks
The association attached an ‘expression of concern’ to an abstract with controversial claims about the safety of mRNA-based COVID-19 vaccines that...
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Could an oral PCSK9 inhibitor be on the horizon?
What if the cholesterol-crushing efficacy of current PCSK9 inhibitors came in a pill instead of a syringe? That’s one possibility for a Merck...
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Empagliflozin a winner in challenging arena of stabilized acute HF
Early in-hospital initiation of SGLT2 inhibitors “should be considered the new standard of care” in most patients with heart failure regardless of...
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Alcoholic drinks stand out in novel trial exploring AFib triggers
The study has limitations, but its results jibe with alcohol’s status as a potential trigger of AFib. Patients’ knowledge of their potential...
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Early SAVR tops watchful waiting in severe, asymptomatic aortic stenosis: AVATAR
The findings potentially apply to TAVR as much as to surgical aortic valve replacement, say observers about the trial that compared early surgery...
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Fully endovascular mitral valve replacement a limited success in feasibility study
Although progress in transcatheter mitral valve replacement has been slow compared with TAVR’s rapid ascent, its transition from a transapical to...
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FDA panel slams Endologix response to stent-graft safety issues
The company argued to skeptical advisors that upgrades to its AAA-repair system have already cut any potential endoleak risk, a long-running...
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FFR-guided PCI falls short vs. surgery in multivessel disease: FAME 3
PCI guided by FFR assessment may have yielded better outcomes in patients with less complex coronary anatomy, researchers say; others doubt the...
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ASNC rejects new chest pain guideline it helped create
“We believe that the document fails to provide unbiased guidance to health care professionals on the optimal evaluation of patients with chest...
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New reports help nail down myocarditis risk with COVID-19 vaccine
Myocarditis linked to the two mRNA SARS-CoV-2 vaccines is rare, usually mild and self-limited, and a lot less likely than the usually more severe...
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Is AFib a stroke cause or innocent bystander? The debate continues
Many believe AFib is a risk marker for stroke, but new evidence suggests it may be a causal risk factor.
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FDA approves Abbott’s Portico valve for TAVR
The approval, based largely on the recently published PORTICO-IDE trial, is for patients with severe symptomatic aortic stenosis at ‘high or...
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Most muscle pain on statins not a drug effect: SAMSON in print
Trial makes a strong case for the pain usually being a nocebo effect.
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Are ESC’s new heart failure guidelines already outdated?
It was hard not to think of the upcoming presentation on EMPEROR-Preserved, with its potentially profound impact on HF management, when new HF...