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Adding ACE inhibitor doesn’t improve outcomes in stable angina and normal LVEF
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Adding the angiotensin-converting enzyme (ACE) inhibitor trandolapril (Mavik) to standard medical treatment of patients with stable angina and normal left ventricular function did not reduce their risk of adverse cardiovascular outcomes. Although higher-risk patients and those with less well controlled risk factors may still benefit from this intervention, this study didn’t assess those groups. (LOE=1b)

 
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Practice Recommendations from Key Studies

PEACE Trial Investigators. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004; 351:2058–2068.

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The Journal of Family Practice - 54(2)
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Practice Recommendations from Key Studies

PEACE Trial Investigators. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004; 351:2058–2068.

Author and Disclosure Information

Practice Recommendations from Key Studies

PEACE Trial Investigators. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004; 351:2058–2068.

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Article PDF
BOTTOM LINE

Adding the angiotensin-converting enzyme (ACE) inhibitor trandolapril (Mavik) to standard medical treatment of patients with stable angina and normal left ventricular function did not reduce their risk of adverse cardiovascular outcomes. Although higher-risk patients and those with less well controlled risk factors may still benefit from this intervention, this study didn’t assess those groups. (LOE=1b)

 
BOTTOM LINE

Adding the angiotensin-converting enzyme (ACE) inhibitor trandolapril (Mavik) to standard medical treatment of patients with stable angina and normal left ventricular function did not reduce their risk of adverse cardiovascular outcomes. Although higher-risk patients and those with less well controlled risk factors may still benefit from this intervention, this study didn’t assess those groups. (LOE=1b)

 
Issue
The Journal of Family Practice - 54(2)
Issue
The Journal of Family Practice - 54(2)
Page Number
105-113
Page Number
105-113
Publications
Publications
Topics
Article Type
Display Headline
Adding ACE inhibitor doesn’t improve outcomes in stable angina and normal LVEF
Display Headline
Adding ACE inhibitor doesn’t improve outcomes in stable angina and normal LVEF
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