Immunotherapy Induces Improvements in PML

Key clinical point: Adoptive transfer of donor-derived T cells represents a potentially life-saving strategy for patients with progressive multifocal leukoencephalopathy.

Major finding: Seven of 12 patients stabilized and, in some cases, experienced significant neurological improvement.

Study details: A pilot study including 12 patients with refractory PML.

Disclosures: The study was funded by NINDS. The investigators disclosed no conflicts related to the study.

Citation: Cortese I et al. AAN 2019, Abstract Plen01.002.

Key clinical point: Adoptive transfer of donor-derived T cells represents a potentially life-saving strategy for patients with progressive multifocal leukoencephalopathy.

Major finding: Seven of 12 patients stabilized and, in some cases, experienced significant neurological improvement.

Study details: A pilot study including 12 patients with refractory PML.

Disclosures: The study was funded by NINDS. The investigators disclosed no conflicts related to the study.

Citation: Cortese I et al. AAN 2019, Abstract Plen01.002.

Key clinical point: Adoptive transfer of donor-derived T cells represents a potentially life-saving strategy for patients with progressive multifocal leukoencephalopathy.

Major finding: Seven of 12 patients stabilized and, in some cases, experienced significant neurological improvement.

Study details: A pilot study including 12 patients with refractory PML.

Disclosures: The study was funded by NINDS. The investigators disclosed no conflicts related to the study.

Citation: Cortese I et al. AAN 2019, Abstract Plen01.002.