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Key clinical point: Compared with radical surgery (RS) alone, RS combined with hyperthermic intraperitoneal chemotherapy (HIPEC) improves the relapse-free survival (RFS) in patients with locally advanced gastric cancer (LAGC).

Major finding: Patients receiving RS+HIPEC vs RS alone had a significantly longer median RFS (not reached vs 22.0 months; χ2 4.468; P  =  .035) and higher 2-year RFS rate (62.9% and 37.8%).

Study details: This retrospective study propensity score-matched patients with LAGC who received RS+HIPEC (n = 106) with those who received RS alone (n = 106).

Disclosures: This study was sponsored by the National Nature Science Foundation of China. The authors declared no conflicts of interest.

Source: Shen C et al. Comparative study of the efficacy and safety of radical surgery with or without hyperthermic intraperitoneal chemotherapy in locally advanced gastric cancer: A propensity score-matching analysis. Ann Surg Oncol. 2022 (Aug 8). Doi: 10.1245/s10434-022-12348-9

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Key clinical point: Compared with radical surgery (RS) alone, RS combined with hyperthermic intraperitoneal chemotherapy (HIPEC) improves the relapse-free survival (RFS) in patients with locally advanced gastric cancer (LAGC).

Major finding: Patients receiving RS+HIPEC vs RS alone had a significantly longer median RFS (not reached vs 22.0 months; χ2 4.468; P  =  .035) and higher 2-year RFS rate (62.9% and 37.8%).

Study details: This retrospective study propensity score-matched patients with LAGC who received RS+HIPEC (n = 106) with those who received RS alone (n = 106).

Disclosures: This study was sponsored by the National Nature Science Foundation of China. The authors declared no conflicts of interest.

Source: Shen C et al. Comparative study of the efficacy and safety of radical surgery with or without hyperthermic intraperitoneal chemotherapy in locally advanced gastric cancer: A propensity score-matching analysis. Ann Surg Oncol. 2022 (Aug 8). Doi: 10.1245/s10434-022-12348-9

Key clinical point: Compared with radical surgery (RS) alone, RS combined with hyperthermic intraperitoneal chemotherapy (HIPEC) improves the relapse-free survival (RFS) in patients with locally advanced gastric cancer (LAGC).

Major finding: Patients receiving RS+HIPEC vs RS alone had a significantly longer median RFS (not reached vs 22.0 months; χ2 4.468; P  =  .035) and higher 2-year RFS rate (62.9% and 37.8%).

Study details: This retrospective study propensity score-matched patients with LAGC who received RS+HIPEC (n = 106) with those who received RS alone (n = 106).

Disclosures: This study was sponsored by the National Nature Science Foundation of China. The authors declared no conflicts of interest.

Source: Shen C et al. Comparative study of the efficacy and safety of radical surgery with or without hyperthermic intraperitoneal chemotherapy in locally advanced gastric cancer: A propensity score-matching analysis. Ann Surg Oncol. 2022 (Aug 8). Doi: 10.1245/s10434-022-12348-9

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Clinical Edge Journal Scan Commentary: Gastric Cancer, September 2022
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