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Key clinical point: Patients with rheumatoid arthritis (RA) and low or moderate disease activity were at a higher risk for hospitalized infections compared with those in remission.

 

Major finding: Compared with patients attaining remission, patients attaining low disease activity (adjusted hazard ratio [aHR] 1.60; 95% CI 1.13-2.27) and moderate disease activity (aHR 1.83; 95% CI 1.29-2.61) were at a higher risk for hospitalized infections.

 

Study details: Findings are from a prospective observational cohort study including 3254 patients with moderate RA from the CorEvitas RA registry.

 

Disclosures: H Yun and JR Curtis declared receiving support from US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. Two authors reported being employees and shareholders of CorEvitas LLC. Several authors reported receiving research funding from or serving on speakers bureaus or as consultants for various sources.

 

Source: Yun H et al. Rheumatoid arthritis disease activity and hospitalized infection in a large U.S. registry. Arthritis Care Res (Hoboken). 2022 (Jul 22). Doi: 10.1002/acr.24984

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Key clinical point: Patients with rheumatoid arthritis (RA) and low or moderate disease activity were at a higher risk for hospitalized infections compared with those in remission.

 

Major finding: Compared with patients attaining remission, patients attaining low disease activity (adjusted hazard ratio [aHR] 1.60; 95% CI 1.13-2.27) and moderate disease activity (aHR 1.83; 95% CI 1.29-2.61) were at a higher risk for hospitalized infections.

 

Study details: Findings are from a prospective observational cohort study including 3254 patients with moderate RA from the CorEvitas RA registry.

 

Disclosures: H Yun and JR Curtis declared receiving support from US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. Two authors reported being employees and shareholders of CorEvitas LLC. Several authors reported receiving research funding from or serving on speakers bureaus or as consultants for various sources.

 

Source: Yun H et al. Rheumatoid arthritis disease activity and hospitalized infection in a large U.S. registry. Arthritis Care Res (Hoboken). 2022 (Jul 22). Doi: 10.1002/acr.24984

Key clinical point: Patients with rheumatoid arthritis (RA) and low or moderate disease activity were at a higher risk for hospitalized infections compared with those in remission.

 

Major finding: Compared with patients attaining remission, patients attaining low disease activity (adjusted hazard ratio [aHR] 1.60; 95% CI 1.13-2.27) and moderate disease activity (aHR 1.83; 95% CI 1.29-2.61) were at a higher risk for hospitalized infections.

 

Study details: Findings are from a prospective observational cohort study including 3254 patients with moderate RA from the CorEvitas RA registry.

 

Disclosures: H Yun and JR Curtis declared receiving support from US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. Two authors reported being employees and shareholders of CorEvitas LLC. Several authors reported receiving research funding from or serving on speakers bureaus or as consultants for various sources.

 

Source: Yun H et al. Rheumatoid arthritis disease activity and hospitalized infection in a large U.S. registry. Arthritis Care Res (Hoboken). 2022 (Jul 22). Doi: 10.1002/acr.24984

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Clinical Edge Journal Scan Commentary: RA September 2022
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