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Key clinical point: Simultaneous resection of primary colonic tumor and hepatic arterial infusion pump (HAIP) implantation are safe in patients with colon cancer and synchronous liver metastases.
Major finding: Grade 3-4 complications were similar between patients who underwent simultaneous colectomy and HAIP placement vs prior colectomy (P = .872), whereas grade 1-2 complications (36.8% vs 19.0%; P < .001) and the rate for surgical site infection (25.6% vs14.7%; P = .022) were significantly higher with simultaneous colectomy and HAIP placement. The median time from pump placement to the start of HAIP chemotherapy was not different between the groups (P = .924).
Study details: Findings are from a retrospective analysis of 398 patients with colon cancer and synchronous liver metastases who underwent resection of the primary colon tumor either simultaneous with HAIP placement (n=258) or prior to HAIP placement (n=116).
Disclosures: This study was partly supported by National Cancer Institute. J Garcia-Aguilar declared receiving honoraria from Johnson & Johnson, Medtronic, and Intuitive Inc.
Source: Verheij FS et al. Ann Surg Oncol. 2021 Nov 9. doi: 10.1245/s10434-021-11029-3.
Key clinical point: Simultaneous resection of primary colonic tumor and hepatic arterial infusion pump (HAIP) implantation are safe in patients with colon cancer and synchronous liver metastases.
Major finding: Grade 3-4 complications were similar between patients who underwent simultaneous colectomy and HAIP placement vs prior colectomy (P = .872), whereas grade 1-2 complications (36.8% vs 19.0%; P < .001) and the rate for surgical site infection (25.6% vs14.7%; P = .022) were significantly higher with simultaneous colectomy and HAIP placement. The median time from pump placement to the start of HAIP chemotherapy was not different between the groups (P = .924).
Study details: Findings are from a retrospective analysis of 398 patients with colon cancer and synchronous liver metastases who underwent resection of the primary colon tumor either simultaneous with HAIP placement (n=258) or prior to HAIP placement (n=116).
Disclosures: This study was partly supported by National Cancer Institute. J Garcia-Aguilar declared receiving honoraria from Johnson & Johnson, Medtronic, and Intuitive Inc.
Source: Verheij FS et al. Ann Surg Oncol. 2021 Nov 9. doi: 10.1245/s10434-021-11029-3.
Key clinical point: Simultaneous resection of primary colonic tumor and hepatic arterial infusion pump (HAIP) implantation are safe in patients with colon cancer and synchronous liver metastases.
Major finding: Grade 3-4 complications were similar between patients who underwent simultaneous colectomy and HAIP placement vs prior colectomy (P = .872), whereas grade 1-2 complications (36.8% vs 19.0%; P < .001) and the rate for surgical site infection (25.6% vs14.7%; P = .022) were significantly higher with simultaneous colectomy and HAIP placement. The median time from pump placement to the start of HAIP chemotherapy was not different between the groups (P = .924).
Study details: Findings are from a retrospective analysis of 398 patients with colon cancer and synchronous liver metastases who underwent resection of the primary colon tumor either simultaneous with HAIP placement (n=258) or prior to HAIP placement (n=116).
Disclosures: This study was partly supported by National Cancer Institute. J Garcia-Aguilar declared receiving honoraria from Johnson & Johnson, Medtronic, and Intuitive Inc.
Source: Verheij FS et al. Ann Surg Oncol. 2021 Nov 9. doi: 10.1245/s10434-021-11029-3.