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Statins prevent strokes in high-risk patients
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In a select group of compliant, high-risk patients, simvastatin (Zocor) slightly reduced the rate of stroke, except in those patients with known cerebrovascular disease. We would need to treat 72 patients for 4.3 years to prevent 1 stroke. (LOE=1b)

 
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Practice Recommendations from Key Studies

Collins R, Armitage J, Parish S, et al. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004; 363:757–767.

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The Journal of Family Practice - 53(7)
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Practice Recommendations from Key Studies

Collins R, Armitage J, Parish S, et al. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004; 363:757–767.

Author and Disclosure Information

Practice Recommendations from Key Studies

Collins R, Armitage J, Parish S, et al. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004; 363:757–767.

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BOTTOM LINE

In a select group of compliant, high-risk patients, simvastatin (Zocor) slightly reduced the rate of stroke, except in those patients with known cerebrovascular disease. We would need to treat 72 patients for 4.3 years to prevent 1 stroke. (LOE=1b)

 
BOTTOM LINE

In a select group of compliant, high-risk patients, simvastatin (Zocor) slightly reduced the rate of stroke, except in those patients with known cerebrovascular disease. We would need to treat 72 patients for 4.3 years to prevent 1 stroke. (LOE=1b)

 
Issue
The Journal of Family Practice - 53(7)
Issue
The Journal of Family Practice - 53(7)
Page Number
522-530
Page Number
522-530
Publications
Publications
Topics
Article Type
Display Headline
Statins prevent strokes in high-risk patients
Display Headline
Statins prevent strokes in high-risk patients
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