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Ximelagatran effective in preventing stroke in a nonvalvular atrial fibrillation
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In this manufacturer-sponsored, open-label study, patients with atrial fibrillation and at increased risk for stroke treated with either ximelagatran or warfarin have comparable outcomes. If these results are confirmed independently, ximelagatran may become the preferred treatment, since it doesn’t require monitoring and may cause fewer bleeding complications. (LOE=2b).

 
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Practice Recommendations from Key Studies

Executive Steering Committee on behalf of the SPORTIF III Investigators. Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial. Lancet 2003; 362:1691–1698.

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The Journal of Family Practice - 53(4)
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Practice Recommendations from Key Studies

Executive Steering Committee on behalf of the SPORTIF III Investigators. Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial. Lancet 2003; 362:1691–1698.

Author and Disclosure Information

Practice Recommendations from Key Studies

Executive Steering Committee on behalf of the SPORTIF III Investigators. Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial. Lancet 2003; 362:1691–1698.

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BOTTOM LINE

In this manufacturer-sponsored, open-label study, patients with atrial fibrillation and at increased risk for stroke treated with either ximelagatran or warfarin have comparable outcomes. If these results are confirmed independently, ximelagatran may become the preferred treatment, since it doesn’t require monitoring and may cause fewer bleeding complications. (LOE=2b).

 
BOTTOM LINE

In this manufacturer-sponsored, open-label study, patients with atrial fibrillation and at increased risk for stroke treated with either ximelagatran or warfarin have comparable outcomes. If these results are confirmed independently, ximelagatran may become the preferred treatment, since it doesn’t require monitoring and may cause fewer bleeding complications. (LOE=2b).

 
Issue
The Journal of Family Practice - 53(4)
Issue
The Journal of Family Practice - 53(4)
Page Number
261-268
Page Number
261-268
Publications
Publications
Topics
Article Type
Display Headline
Ximelagatran effective in preventing stroke in a nonvalvular atrial fibrillation
Display Headline
Ximelagatran effective in preventing stroke in a nonvalvular atrial fibrillation
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