David S. Chun, PharmD

Treatment with either fluoxetine or nortripty-line for 12 weeks during the first 6 months poststroke reduced the mortality risk of both depressed and nondepressed patients. Strong consideration should be given to treating clinically depressed and nondepressed post-stroke patients who are at significant risk of developing depression (family history or personal history of mood disorders) with antidepressant medication.

Treatment with either fluoxetine or nortripty-line for 12 weeks during the first 6 months poststroke reduced the mortality risk of both depressed and nondepressed patients. Strong consideration should be given to treating clinically depressed and nondepressed post-stroke patients who are at significant risk of developing depression (family history or personal history of mood disorders) with antidepressant medication.

Treatment with either fluoxetine or nortripty-line for 12 weeks during the first 6 months poststroke reduced the mortality risk of both depressed and nondepressed patients. Strong consideration should be given to treating clinically depressed and nondepressed post-stroke patients who are at significant risk of developing depression (family history or personal history of mood disorders) with antidepressant medication.