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Could nivolumab prevent oral cancer in high-risk patients?
Immunotherapy as a preventative strategy, as first-line or secondary, should be further explored.
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‘Unprecedented’ responses to neoadjuvant treatment in dMMR colon cancer
Neoadjuvant immunotherapy “has the potential to become standard of care” in these patients.
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Cabozantinib boosts dual immunotherapy in advanced RCC
The new study suggests triplet therapy may become a new standard of care in advanced renal cell carcinoma.
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First drug for desmoid tumors: ‘Impressive’ data for nirogacestat
Nirogacestat has shown a significant improvement in progression-free survival and also a reduction in symptoms and better quality of life.
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Dupilumab offers ‘clinically meaningful’ improvements in prurigo nodularis
Although various treatments are used off label for many patients with moderate to severe PN, disease control is inadequate, and the patients are “...
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Test Lp(a) levels to inform ASCVD management: NLA statement
“The question in the scientific community is: What role does that particular biomarker play in terms of causing serious heart disease, stroke, and...
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New ESC cardio-oncology guideline aims to reduce cardiotoxicity
A “very strong theme throughout the guideline is risk assessment, and the fact that that risk is dynamic.”
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Men at higher risk than are women for many cancers: Why?
The difference can only partly be explained by risky behaviors and carcinogenic exposure.
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Mindfulness ‘changes the biology’ of pain
Those who completed a mindfulness-based stress reduction program had a reduction in a brain signature linked to the sensory intensity of pain.
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Poor sleep raises risk for fatty liver disease
Late bedtimes, snoring, and prolonged daytime napping were significantly associated with MAFLD,
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Rethinking histology as treatment target in ulcerative colitis
Active histology should not be used as a treatment target in ulcerative colitis, as it seems to have no impact on the risk of clinical relapse.
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Comorbidities key to serious infections with IBD treatment
Older IBD patients with comorbidities are less likely to be hospitalized due to an infection if they are treated with vedolizumab or ustekinumab...
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New update focuses on NAFLD in lean people
Lean individuals older than 40 with type 2 diabetes should be screened for NAFLD, urge experts.
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U.S. hot, cold spots of young-onset CRC may help target interventions
“Additional factors like proximity to primary care, gastroenterology, and cancer care facilities or novel environmental exposures may contribute...
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Quicker remission with tofacitinib versus vedolizumab in ulcerative colitis: study
Tofacitinib achieves higher clinical and biochemical remission rates than vedolizumab for patients with anti–TNF-exposed ulcerative colitis,...