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Exercise timing may dictate obesity, type 2 diabetes risk
People who exercised in the morning had a lower body mass index than those who exercised at other times, even though they were more sedentary.
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Many patients with NSCLC receive immunotherapy ‘indefinitely’ – Are they benefiting?
Without “incontrovertible evidence” that immunotherapy should stop at 2 years, “many, many, many patients and clinicians are going to favor...
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Proposed TNM update could shift staging for lung cancers
Lung cancers, particularly those with T1 disease, could be reclassified into a different overall stage if proposed adaptations to the N and M...
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Osimertinib plus chemo ups PFS, toxicity in first line
Combining osimertinib with chemotherapy improved progression-free survival in EGFR-mutated non–small cell lung cancer, new interim data show, but...
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Novel ADC offers hope in heavily pretreated NSCLC
A phase 2 trial found that almost 30% of patients receiving antibody-drug conjugate patritumab deruxtecan achieved an objective response, and...
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Probing the link between GERD and anxiety and depression
An analysis suggested that a genetic risk for GERD increased the risk of developing depression or anxiety and vice versa.
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Unlocking the secrets of brown fat
Since obesity results from an imbalance between energy intake and energy expenditure, one model proposes that brown adipocytes rebalance this...
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Probiotics improve nonmotor symptoms of Parkinson’s
Participants taking the probiotic also saw a reduced delay in “time to on” of treatment with levodopa, thus reducing the delay until effectiveness...
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Even an hour’s walk a week lowers risk in type 2 diabetes
“Our findings are particularly promising for neuropathy since, currently, no disease-modifying treatment exists, and there are limited preventive...
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Both too much and not enough sleep raises T2D risk
“These findings underpin the importance of promoting healthy sleep habits to avoid sleep deprivation.”
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Simple blood test may predict heart and kidney risk in T2D
“Three out of the four biomarkers are already clinically and commercially available,” while the fourth, for insulin-like growth factor binding...
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New guide for acute liver failure urges early treatment, transplant referral
The clinical guidelines focus on the diagnosis and management of patients with acute liver failure.
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Two-pronged approach needed in alcohol-associated hepatitis
Patients are likely to carry a dual diagnosis of liver disease and alcohol use disorder.
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Anticoagulants for cancer-related VTE: What works best?
These data may “help facilitate shared decision-marking and inform clinical guidelines for the treatment of such patients.”
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Retinal thickness a new predictor of MS disability?
The imaging technique cannot be used for all patients and is currently not widely available.