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BREEZE-AD-PEDS: First data for baricitinib in childhood eczema reported
Treatment with the oral JAK inhibitor was significantly more effective than placebo only with the highest dose evaluated.
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Alopecia areata: Positive results reported for two investigational JAK inhibitors
“This is truly transformative therapy,” one of the investigators, Brett King, MD, PhD, said.
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Study identifies skin biomarkers that predict newborn eczema risk
"We are able to identify predictive immune biomarkers of atopic dermatitis using a noninvasive method," the investigator said.
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Ezetimibe-statin combo lowers liver fat in open-label trial
A significant 5.8% decrease in hepatic steatosis was seen after 24 weeks’ treatment with ezetimibe and rosuvastatin comparing baseline with end of...
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Early age at hysterectomy ups type 2 diabetes risk
Having a hysterectomy appears to increase the risk of incident type 2 diabetes, particularly in younger women, and if the ovaries are removed at...
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Mothers’ diabetes linked to ADHD in their children
A small increased risk of ADHD in children born to mothers with diabetes, including pregestational diabetes and gestational diabetes, has been...
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Apremilast alleviates severe psoriasis in some children, data show
“In this randomized, placebo-controlled trial, oral apremilast demonstrated effectiveness and was well tolerated.”
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Hope shines bright for hidradenitis suppurativa treatments
Research into HS is "an incredibly active field at this moment," said Alexa B. Kimball, MD, MPH.
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Experts express caution over
type 2 diabetes/tea-drinking claim
Drinking four cups of tea a day was linked to a 17% lower risk for developing type 2 diabetes in a study, but experts warn these data are...
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Roflumilast foam effectively eases seborrheic dermatitis
The study evaluated a foam formulation of roflumilast, a PDE4 inhibitor that is available for topical use in a cream formulation that was recently...
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Overall survival dips with vitamin D deficiency in melanoma
The research adds to existing evidence that “vitamin D levels can play an important and independent role in patients’ survival outcomes.”
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Finding HBV ‘cure’ may mean going ‘back to the drawing board’
Development of new HBV drugs looks more complicated than initially expected, and it’s time to refine and refocus goals, according to one...
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Statins in NAFLD: Taking a closer look at benefits
Statins could have multiple benefits in NAFLD, but there has been little insight into how they may be exerting such effects.
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Phase 3 data shows bulevirtide benefit in hepatitis D
“For us in the hepatitis D field, it is a really exciting time; it’s completely novel data and game-changing for patients.”
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Pemvidutide promising for fatty liver disease
Weight loss and multiple improvements in lipid parameters linked to nonalcoholic fatty liver disease were seen in a phase 1 trial.