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Use psychoeducational family therapy to help families cope with autism
Treating a family in crisis because of a difficult-to-manage family member with autism spectrum disorder (ASD) can be overwhelming. The family often is desperate and exhausted and, therefore, can be overly needy, demanding, and disorganized. Psychiatrists often are asked to intervene with medication, even though there are no drugs to treat core symptoms of ASD. At best, medication can ease associated symptoms, such as insomnia. However, when coupled with reasonable medication management, psychoeducational family therapy can be an effective, powerful intervention during initial and follow-up medication visits.
Families of ASD patients often show dysfunctional patterns: poor interpersonal and generational boundaries, closed family systems, pathological triangulations, fused and disengaged relationships, resentments, etc. It is easy to assume that an autistic patient’s behavior problems are related to these dysfunctional patterns, and these patterns are caused by psychopathology within the family. In the 1970s and 1980s researchers began to challenge this same assumption in families of patients with schizophrenia and found that the illness shaped family patterns, not the reverse. Illness exacerbations could be minimized by teaching families to reduce their expressed emotions. In addition, research clinicians stopped blaming family members and began describing family dysfunction as a “normal response” to severe psychiatric illness.1
Families of autistic individuals should learn to avoid coercive patterns and clarify interpersonal boundaries. Family members also should understand that dysfunctional patterns are a normal response to illness, these patterns can be corrected, and the correction can lead to improved management of ASD.
Psychoeducational family therapy provides an excellent framework for this family-psychiatrist interaction. Time-consuming, complex, expressive family therapies are not recommended because they tend to heighten expressed emotions.
Consider the following tips when providing psychoeducational family therapy:
• Remember that the extreme stress these families experience is based in reality. Lower functioning ASD patients might not sleep, require constant supervision, and cannot tolerate even minor frustrations.
• Respect the family’s ego defenses as a normal response to stress. Expect to feel some initial frustration and anxiety when working with overwhelmed families.
• Normalize negative feelings within the family. Everyone goes through anger, grief, and hopelessness when handling such a stressful situation.
• Avoid blaming dysfunctional patterns on individuals. Dysfunctional behavior is a normal response to the stress of caring for a family member with ASD.
• Empower the family. Remind the family that they know the patient best, so help them to find their own solutions to behavioral problems.
• Focus on the basics including establishing normal sleeping patterns and regular household routines.
• Educate the family about low sensory stimulation in the home. ASD patients are easily overwhelmed by sensory stimulation which can lead to lower frustration tolerance.
Disclosure
The author reports no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
Reference
1. Nichols MP. Family therapy: concepts and methods. 7th ed. Boston, MA: Pearson Education; 2006.
Treating a family in crisis because of a difficult-to-manage family member with autism spectrum disorder (ASD) can be overwhelming. The family often is desperate and exhausted and, therefore, can be overly needy, demanding, and disorganized. Psychiatrists often are asked to intervene with medication, even though there are no drugs to treat core symptoms of ASD. At best, medication can ease associated symptoms, such as insomnia. However, when coupled with reasonable medication management, psychoeducational family therapy can be an effective, powerful intervention during initial and follow-up medication visits.
Families of ASD patients often show dysfunctional patterns: poor interpersonal and generational boundaries, closed family systems, pathological triangulations, fused and disengaged relationships, resentments, etc. It is easy to assume that an autistic patient’s behavior problems are related to these dysfunctional patterns, and these patterns are caused by psychopathology within the family. In the 1970s and 1980s researchers began to challenge this same assumption in families of patients with schizophrenia and found that the illness shaped family patterns, not the reverse. Illness exacerbations could be minimized by teaching families to reduce their expressed emotions. In addition, research clinicians stopped blaming family members and began describing family dysfunction as a “normal response” to severe psychiatric illness.1
Families of autistic individuals should learn to avoid coercive patterns and clarify interpersonal boundaries. Family members also should understand that dysfunctional patterns are a normal response to illness, these patterns can be corrected, and the correction can lead to improved management of ASD.
Psychoeducational family therapy provides an excellent framework for this family-psychiatrist interaction. Time-consuming, complex, expressive family therapies are not recommended because they tend to heighten expressed emotions.
Consider the following tips when providing psychoeducational family therapy:
• Remember that the extreme stress these families experience is based in reality. Lower functioning ASD patients might not sleep, require constant supervision, and cannot tolerate even minor frustrations.
• Respect the family’s ego defenses as a normal response to stress. Expect to feel some initial frustration and anxiety when working with overwhelmed families.
• Normalize negative feelings within the family. Everyone goes through anger, grief, and hopelessness when handling such a stressful situation.
• Avoid blaming dysfunctional patterns on individuals. Dysfunctional behavior is a normal response to the stress of caring for a family member with ASD.
• Empower the family. Remind the family that they know the patient best, so help them to find their own solutions to behavioral problems.
• Focus on the basics including establishing normal sleeping patterns and regular household routines.
• Educate the family about low sensory stimulation in the home. ASD patients are easily overwhelmed by sensory stimulation which can lead to lower frustration tolerance.
Disclosure
The author reports no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
Treating a family in crisis because of a difficult-to-manage family member with autism spectrum disorder (ASD) can be overwhelming. The family often is desperate and exhausted and, therefore, can be overly needy, demanding, and disorganized. Psychiatrists often are asked to intervene with medication, even though there are no drugs to treat core symptoms of ASD. At best, medication can ease associated symptoms, such as insomnia. However, when coupled with reasonable medication management, psychoeducational family therapy can be an effective, powerful intervention during initial and follow-up medication visits.
Families of ASD patients often show dysfunctional patterns: poor interpersonal and generational boundaries, closed family systems, pathological triangulations, fused and disengaged relationships, resentments, etc. It is easy to assume that an autistic patient’s behavior problems are related to these dysfunctional patterns, and these patterns are caused by psychopathology within the family. In the 1970s and 1980s researchers began to challenge this same assumption in families of patients with schizophrenia and found that the illness shaped family patterns, not the reverse. Illness exacerbations could be minimized by teaching families to reduce their expressed emotions. In addition, research clinicians stopped blaming family members and began describing family dysfunction as a “normal response” to severe psychiatric illness.1
Families of autistic individuals should learn to avoid coercive patterns and clarify interpersonal boundaries. Family members also should understand that dysfunctional patterns are a normal response to illness, these patterns can be corrected, and the correction can lead to improved management of ASD.
Psychoeducational family therapy provides an excellent framework for this family-psychiatrist interaction. Time-consuming, complex, expressive family therapies are not recommended because they tend to heighten expressed emotions.
Consider the following tips when providing psychoeducational family therapy:
• Remember that the extreme stress these families experience is based in reality. Lower functioning ASD patients might not sleep, require constant supervision, and cannot tolerate even minor frustrations.
• Respect the family’s ego defenses as a normal response to stress. Expect to feel some initial frustration and anxiety when working with overwhelmed families.
• Normalize negative feelings within the family. Everyone goes through anger, grief, and hopelessness when handling such a stressful situation.
• Avoid blaming dysfunctional patterns on individuals. Dysfunctional behavior is a normal response to the stress of caring for a family member with ASD.
• Empower the family. Remind the family that they know the patient best, so help them to find their own solutions to behavioral problems.
• Focus on the basics including establishing normal sleeping patterns and regular household routines.
• Educate the family about low sensory stimulation in the home. ASD patients are easily overwhelmed by sensory stimulation which can lead to lower frustration tolerance.
Disclosure
The author reports no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
Reference
1. Nichols MP. Family therapy: concepts and methods. 7th ed. Boston, MA: Pearson Education; 2006.
Reference
1. Nichols MP. Family therapy: concepts and methods. 7th ed. Boston, MA: Pearson Education; 2006.
Educate patients about proper disposal of unused Rx medications—for their safety
Patients often tell clinicians that they used their “left-over” medications from previous refills, or that a family member shared medication with them. Other patients, who are non-adherent or have had a recent medication change, might reveal that they have some unused pills at home. As clinicians, what does this practice by our patients mean for us?
Prescription drug abuse is an emerging crisis, and drug diversion is a significant contributing factor.1 According to the Substance Abuse and Mental Health Services Administration’s National Survey on Drug Use and Health,2 in 2011 and 2012, on average, more than one-half of participants age ≥12 who used a pain reliever, tranquilizer, stimulant, or sedative non-medically obtained their most recently used drug “from a friend or relative for free.”
Unused, expired, and “extra” medications pose a significant risk for diversion, abuse, and accidental overdose.3 According to the Prescription Drug Abuse Prevention Plan,1 proper medication disposal is a major problem that needs action to help reduce prescription drug abuse.
Regrettably, <20% of patients receive advice on medication disposal from their health care provider,4 even though clinicians have an opportunity to educate patients and their caregivers on appropriate use, and safe disposal of, medications—in particular, controlled substances.
What should we emphasize to our patients about disposing of medications when it’s necessary?
Teach responsible use
Stress that medications prescribed for the patient are for his (her) use alone and should not be shared with friends or family. Sharing might seem kind and generous, but it can be dangerous. Medications should be used only at the prescribed dosage and frequency and for the recommended duration. If the medication causes an adverse effect or other problem, instruct the patient to talk to you before making any changes to the established regimen.
Emphasize safe disposal
Follow instructions. The label on medication bottles or other containers often has specific instructions on how to properly store, and even dispose of, the drug. Advise your patient to follow instructions on the label carefully.
Participate in a take-back program. The U.S. Drug Enforcement Administration (DEA) sponsors several kinds of drug take-back programs, including permanent locations where unused prescriptions are collected; 1-day events; and mail-in/ship-back programs.
The National Prescription Drug Take-Back Initiative is one such program that collects unused or expired medications on “Take Back Days.” On such days, DEA-coordinated collection sites nationwide accept unneeded pills, including prescription painkillers and other controlled substances, for disposal only when law enforcement personnel are present. In 2014, this program collected 780,158 lb of prescribed controlled medications.5
Patients can get more information about these programs by contacting a local pharmacy or their household trash and recycling service division.1,6
Discard medications properly in trash. An acceptable household strategy for disposing of prescription drugs is to mix the medication with an undesirable substance, such as used cat litter or coffee grounds, place the mixture in a sealed plastic bag or disposable container with a lid, and then place it in the trash.
Don’t flush. People sometimes flush unused medications down the toilet or drain. The current recommendation is against flushing unless instructions on the bottle specifically say to do so. Flushing is appropriate for disposing of some medications such as opiates, thereby minimizing the risk of accidental overdose or misuse.6 It is important to remember that most municipal sewage treatment plans do not have the ability to extract pharmaceuticals from wastewater.7
Discard empty bottles. It is important to discard pill bottles once they are empty and to remove any identifiable personal information from the label. Educate patients not to use empty pill bottles to store or transport other medications; this practice might result in accidental ingestion of the wrong medication or dose.These methods of disposal are in accordance with federal, state, and local regulations, as well as human and environmental safety standards. Appropriate disposal decreases contamination of soil and bodies of water with active pharmaceutical ingredients, thereby minimizing people’s and aquatic animals’ chronic exposure to low levels of drugs.3
Encourage patients to seek drug safety information. Patients might benefit from the information and services provided by:
• National Council on Patient Information and Education (www.talkaboutrx.org)
• Medication Use Safety Training for Seniors (www.mustforseniors.org), a nationwide initiative to promote medication education and safety in the geriatric population through an interactive program.
Remember: Although prescribing medications is strictly regulated, particularly for controlled substances, those regulations do little to prevent diversion of medications after they’ve been prescribed. Educating patients and their caregivers about safe disposal can help protect them, their family, and others.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Epidemic: responding to America’s prescription drug abuse crisis. http://www.whitehouse.gov/sites/default/files/ ondcp/issues-content/prescription-drugs/rx_abuse_plan. pdf. Published 2011. Accessed January 29, 2015.
2. Results from the 2012 National Survey on Drug Use and Health: summary of national findings and detailed tables. http://archive.samhsa.gov/data/ NSDUH/2012SummNatFindDetTables/Index.aspx. Updated October 12, 2013. Accessed February 12, 2015.
3. Daughton CG, Ruhoy IS. Green pharmacy and pharmEcovigilance: prescribing and the planet. Expert Rev Clin Pharmacol. 2011;4(2):211-232.
4. Seehusen DA, Edwards J. Patient practices and beliefs concerning disposal of medications. J Am Board Fam Med. 2006;19(6):542-547.
5. DEA’S National Prescription Drug Take-Back Days meet a growing need for Americans. Drug Enforcement Administration. http://www.dea.gov/divisions/hq/2014/ hq050814.shtml. Published May 8, 2014. Accessed January 29, 2015.
6. How to dispose of unused medicines. FDA Consumer Health Information. http://www.fda.gov/downloads/ Drugs/ResourcesForYou/Consumers/BuyingUsing MedicineSafely/UnderstandingOver-the-Counter Medicines/ucm107163.pdf. Published April 2011. Accessed January 29, 2015.
7. Herring ME, Shah SK, Shah SK, et al. Current regulations and modest proposals regarding disposal of unused opioids and other controlled substances. J Am Osteopath Assoc. 2008;108(7):338-343.
Back Initiative, Take Back Days, discard medications
Patients often tell clinicians that they used their “left-over” medications from previous refills, or that a family member shared medication with them. Other patients, who are non-adherent or have had a recent medication change, might reveal that they have some unused pills at home. As clinicians, what does this practice by our patients mean for us?
Prescription drug abuse is an emerging crisis, and drug diversion is a significant contributing factor.1 According to the Substance Abuse and Mental Health Services Administration’s National Survey on Drug Use and Health,2 in 2011 and 2012, on average, more than one-half of participants age ≥12 who used a pain reliever, tranquilizer, stimulant, or sedative non-medically obtained their most recently used drug “from a friend or relative for free.”
Unused, expired, and “extra” medications pose a significant risk for diversion, abuse, and accidental overdose.3 According to the Prescription Drug Abuse Prevention Plan,1 proper medication disposal is a major problem that needs action to help reduce prescription drug abuse.
Regrettably, <20% of patients receive advice on medication disposal from their health care provider,4 even though clinicians have an opportunity to educate patients and their caregivers on appropriate use, and safe disposal of, medications—in particular, controlled substances.
What should we emphasize to our patients about disposing of medications when it’s necessary?
Teach responsible use
Stress that medications prescribed for the patient are for his (her) use alone and should not be shared with friends or family. Sharing might seem kind and generous, but it can be dangerous. Medications should be used only at the prescribed dosage and frequency and for the recommended duration. If the medication causes an adverse effect or other problem, instruct the patient to talk to you before making any changes to the established regimen.
Emphasize safe disposal
Follow instructions. The label on medication bottles or other containers often has specific instructions on how to properly store, and even dispose of, the drug. Advise your patient to follow instructions on the label carefully.
Participate in a take-back program. The U.S. Drug Enforcement Administration (DEA) sponsors several kinds of drug take-back programs, including permanent locations where unused prescriptions are collected; 1-day events; and mail-in/ship-back programs.
The National Prescription Drug Take-Back Initiative is one such program that collects unused or expired medications on “Take Back Days.” On such days, DEA-coordinated collection sites nationwide accept unneeded pills, including prescription painkillers and other controlled substances, for disposal only when law enforcement personnel are present. In 2014, this program collected 780,158 lb of prescribed controlled medications.5
Patients can get more information about these programs by contacting a local pharmacy or their household trash and recycling service division.1,6
Discard medications properly in trash. An acceptable household strategy for disposing of prescription drugs is to mix the medication with an undesirable substance, such as used cat litter or coffee grounds, place the mixture in a sealed plastic bag or disposable container with a lid, and then place it in the trash.
Don’t flush. People sometimes flush unused medications down the toilet or drain. The current recommendation is against flushing unless instructions on the bottle specifically say to do so. Flushing is appropriate for disposing of some medications such as opiates, thereby minimizing the risk of accidental overdose or misuse.6 It is important to remember that most municipal sewage treatment plans do not have the ability to extract pharmaceuticals from wastewater.7
Discard empty bottles. It is important to discard pill bottles once they are empty and to remove any identifiable personal information from the label. Educate patients not to use empty pill bottles to store or transport other medications; this practice might result in accidental ingestion of the wrong medication or dose.These methods of disposal are in accordance with federal, state, and local regulations, as well as human and environmental safety standards. Appropriate disposal decreases contamination of soil and bodies of water with active pharmaceutical ingredients, thereby minimizing people’s and aquatic animals’ chronic exposure to low levels of drugs.3
Encourage patients to seek drug safety information. Patients might benefit from the information and services provided by:
• National Council on Patient Information and Education (www.talkaboutrx.org)
• Medication Use Safety Training for Seniors (www.mustforseniors.org), a nationwide initiative to promote medication education and safety in the geriatric population through an interactive program.
Remember: Although prescribing medications is strictly regulated, particularly for controlled substances, those regulations do little to prevent diversion of medications after they’ve been prescribed. Educating patients and their caregivers about safe disposal can help protect them, their family, and others.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
Patients often tell clinicians that they used their “left-over” medications from previous refills, or that a family member shared medication with them. Other patients, who are non-adherent or have had a recent medication change, might reveal that they have some unused pills at home. As clinicians, what does this practice by our patients mean for us?
Prescription drug abuse is an emerging crisis, and drug diversion is a significant contributing factor.1 According to the Substance Abuse and Mental Health Services Administration’s National Survey on Drug Use and Health,2 in 2011 and 2012, on average, more than one-half of participants age ≥12 who used a pain reliever, tranquilizer, stimulant, or sedative non-medically obtained their most recently used drug “from a friend or relative for free.”
Unused, expired, and “extra” medications pose a significant risk for diversion, abuse, and accidental overdose.3 According to the Prescription Drug Abuse Prevention Plan,1 proper medication disposal is a major problem that needs action to help reduce prescription drug abuse.
Regrettably, <20% of patients receive advice on medication disposal from their health care provider,4 even though clinicians have an opportunity to educate patients and their caregivers on appropriate use, and safe disposal of, medications—in particular, controlled substances.
What should we emphasize to our patients about disposing of medications when it’s necessary?
Teach responsible use
Stress that medications prescribed for the patient are for his (her) use alone and should not be shared with friends or family. Sharing might seem kind and generous, but it can be dangerous. Medications should be used only at the prescribed dosage and frequency and for the recommended duration. If the medication causes an adverse effect or other problem, instruct the patient to talk to you before making any changes to the established regimen.
Emphasize safe disposal
Follow instructions. The label on medication bottles or other containers often has specific instructions on how to properly store, and even dispose of, the drug. Advise your patient to follow instructions on the label carefully.
Participate in a take-back program. The U.S. Drug Enforcement Administration (DEA) sponsors several kinds of drug take-back programs, including permanent locations where unused prescriptions are collected; 1-day events; and mail-in/ship-back programs.
The National Prescription Drug Take-Back Initiative is one such program that collects unused or expired medications on “Take Back Days.” On such days, DEA-coordinated collection sites nationwide accept unneeded pills, including prescription painkillers and other controlled substances, for disposal only when law enforcement personnel are present. In 2014, this program collected 780,158 lb of prescribed controlled medications.5
Patients can get more information about these programs by contacting a local pharmacy or their household trash and recycling service division.1,6
Discard medications properly in trash. An acceptable household strategy for disposing of prescription drugs is to mix the medication with an undesirable substance, such as used cat litter or coffee grounds, place the mixture in a sealed plastic bag or disposable container with a lid, and then place it in the trash.
Don’t flush. People sometimes flush unused medications down the toilet or drain. The current recommendation is against flushing unless instructions on the bottle specifically say to do so. Flushing is appropriate for disposing of some medications such as opiates, thereby minimizing the risk of accidental overdose or misuse.6 It is important to remember that most municipal sewage treatment plans do not have the ability to extract pharmaceuticals from wastewater.7
Discard empty bottles. It is important to discard pill bottles once they are empty and to remove any identifiable personal information from the label. Educate patients not to use empty pill bottles to store or transport other medications; this practice might result in accidental ingestion of the wrong medication or dose.These methods of disposal are in accordance with federal, state, and local regulations, as well as human and environmental safety standards. Appropriate disposal decreases contamination of soil and bodies of water with active pharmaceutical ingredients, thereby minimizing people’s and aquatic animals’ chronic exposure to low levels of drugs.3
Encourage patients to seek drug safety information. Patients might benefit from the information and services provided by:
• National Council on Patient Information and Education (www.talkaboutrx.org)
• Medication Use Safety Training for Seniors (www.mustforseniors.org), a nationwide initiative to promote medication education and safety in the geriatric population through an interactive program.
Remember: Although prescribing medications is strictly regulated, particularly for controlled substances, those regulations do little to prevent diversion of medications after they’ve been prescribed. Educating patients and their caregivers about safe disposal can help protect them, their family, and others.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Epidemic: responding to America’s prescription drug abuse crisis. http://www.whitehouse.gov/sites/default/files/ ondcp/issues-content/prescription-drugs/rx_abuse_plan. pdf. Published 2011. Accessed January 29, 2015.
2. Results from the 2012 National Survey on Drug Use and Health: summary of national findings and detailed tables. http://archive.samhsa.gov/data/ NSDUH/2012SummNatFindDetTables/Index.aspx. Updated October 12, 2013. Accessed February 12, 2015.
3. Daughton CG, Ruhoy IS. Green pharmacy and pharmEcovigilance: prescribing and the planet. Expert Rev Clin Pharmacol. 2011;4(2):211-232.
4. Seehusen DA, Edwards J. Patient practices and beliefs concerning disposal of medications. J Am Board Fam Med. 2006;19(6):542-547.
5. DEA’S National Prescription Drug Take-Back Days meet a growing need for Americans. Drug Enforcement Administration. http://www.dea.gov/divisions/hq/2014/ hq050814.shtml. Published May 8, 2014. Accessed January 29, 2015.
6. How to dispose of unused medicines. FDA Consumer Health Information. http://www.fda.gov/downloads/ Drugs/ResourcesForYou/Consumers/BuyingUsing MedicineSafely/UnderstandingOver-the-Counter Medicines/ucm107163.pdf. Published April 2011. Accessed January 29, 2015.
7. Herring ME, Shah SK, Shah SK, et al. Current regulations and modest proposals regarding disposal of unused opioids and other controlled substances. J Am Osteopath Assoc. 2008;108(7):338-343.
1. Epidemic: responding to America’s prescription drug abuse crisis. http://www.whitehouse.gov/sites/default/files/ ondcp/issues-content/prescription-drugs/rx_abuse_plan. pdf. Published 2011. Accessed January 29, 2015.
2. Results from the 2012 National Survey on Drug Use and Health: summary of national findings and detailed tables. http://archive.samhsa.gov/data/ NSDUH/2012SummNatFindDetTables/Index.aspx. Updated October 12, 2013. Accessed February 12, 2015.
3. Daughton CG, Ruhoy IS. Green pharmacy and pharmEcovigilance: prescribing and the planet. Expert Rev Clin Pharmacol. 2011;4(2):211-232.
4. Seehusen DA, Edwards J. Patient practices and beliefs concerning disposal of medications. J Am Board Fam Med. 2006;19(6):542-547.
5. DEA’S National Prescription Drug Take-Back Days meet a growing need for Americans. Drug Enforcement Administration. http://www.dea.gov/divisions/hq/2014/ hq050814.shtml. Published May 8, 2014. Accessed January 29, 2015.
6. How to dispose of unused medicines. FDA Consumer Health Information. http://www.fda.gov/downloads/ Drugs/ResourcesForYou/Consumers/BuyingUsing MedicineSafely/UnderstandingOver-the-Counter Medicines/ucm107163.pdf. Published April 2011. Accessed January 29, 2015.
7. Herring ME, Shah SK, Shah SK, et al. Current regulations and modest proposals regarding disposal of unused opioids and other controlled substances. J Am Osteopath Assoc. 2008;108(7):338-343.
Back Initiative, Take Back Days, discard medications
Back Initiative, Take Back Days, discard medications
Cloud-based systems can help secure patient information
Physicians hardly need the Health Insurance Portability and Accountability Act (HIPAA) to remind them how important it is to safeguard their patients’ records. Physicians understand that patient information is sensitive and it would be disastrous if their files became public or fell into the wrong hands. However, the use of health information technology to record patient information, although beneficial for medical professionals and patients, poses risks to patient privacy.1
HIPAA requires clinicians and health care systems to protect patient information, whether it is maintained in an electronic health records system, stored on a mobile device, or transmitted via e-mail to another physician. The U.S. Department of Health and Human Services will increase HIPAA audits this year to make sure that medical practices have taken measures to protect their patients’ health information. Physicians and other clinicians can take advantage of cloud-based file-sharing services, such as Dropbox, without running afoul of HIPAA.
Mobile computing, the cloud, and patient information: A risky combination
Although mobile computing and cloud-based file-sharing sites such as Dropbox and Google Drive allow physicians to take notes on a tablet, annotate those notes on a laptop, and share them with a physician who views them on his (her) desktop, this free flow of information makes it more difficult to stay compliant with HIPAA.
Dropbox and other file-sharing services encrypt documents while they’re stored in the cloud but the files are unprotected when downloaded to a device. E-mail, which isn’t as versatile or useful as these services, also is not HIPAA-compliant unless the files are encrypted.
Often, small psychiatric practices use these online services and e-mail even if they’re aware of the risks because they don’t have time to research a better solution. Or they might resort to faxing or even snail-mailing documents, losing out on the increased productivity that the cloud can provide.
Secure technologies satisfy auditors
A number of tools exist to help physicians seamlessly integrate the encryption necessary to keep their patients’ records safe and meet HIPAA security requirements. Here’s a look at 3 options.
Sookasa (plus Dropbox). One option is to invest in a software product designed to encrypt documents shared through cloud-based services. This type of software creates a compliance “shield” around files stored on the cloud, converting files into HIPAA safe havens. The files are encrypted when synced to new devices or shared with other users, meaning they’re protected no matter where they reside.2
Sookasa is an online service that encrypts files shared and stored in Dropbox. The company plans to extend its support to other popular cloud services such as Google Drive and Microsoft OneDrive. Sookasa also audits and controls access to encrypted files, so that patient data can be blocked even if a device is lost or sto len. Sookasa users also can share files via e-mail with added encryption and authentication to make sure only the authorized receiver gets the documents.2
TigerText. Regular SMS text messages on your mobile phone aren’t compliant with HIPAA, but TigerText replicates the texting experience in a secure way. Instead of being stored on your mobile phone, messages sent through TigerText are stored on the company’s servers. Messages sent through the application can’t be saved, copied, or forwarded to other recipients. TigerText messages also are deleted, either after a set time period or after they’ve been read. Because the messages aren’t stored on phones, a lost or stolen phone won’t result in a data breach and a HIPAA violation.3
Secure text messaging won’t help physicians store and manage large amounts of patient files, but it’s a must-have if they use texting to communicate about patient care.
DataMotion SecureMail provides e-mail encryption services to health care organizations and other enterprises. Using a decryption key, authorized users can open and read the encrypted e-mails, which are HIPAA-compliant.4 This method is superior to other services that encrypt e-mails on the server. Several providers, such as Google’s e-mail encryption service Postini, ensure that e-mails are encrypted when they are stored on the server; however, the body text and attachments included in specific e-mails are not encrypted on the senders’ and receivers’ devices. If you lose a connected device, you would still be at risk of a HIPAA breach.
DataMotion’s SecureMail provides detailed tracking and logging of e-mails, which is necessary for auditing purposes. The product also works on mobile devices.
E-mail is a helpful tool for quickly sharing files and an e-mail encryption product such as SecureMail makes it possible to do so securely. Other e-mail encryption products do not securely store and back up all files in a centralized way.
DisclosureDr. Cidon is CEO and Co-founder of Sookasa.
1. U.S. Department of Health and Human Services. HIPAA privacy, security, and breach notification adult program. http://www.hhs.gov/ocr/privacy/hipaa/enforcement/ audit. Accessed February 12, 2015.
2. Sookasa Web site. How it works. https://www.sookasa. com/how-it-works. Accessed February 12, 2015.
3. TigerText Web site. http://www.tigertext.com. Accessed February 12, 2015.
4. DataMotion Web site. http://datamotion.com/products/ securemail/securemail-desktop. Accessed February 12, 2015.
Physicians hardly need the Health Insurance Portability and Accountability Act (HIPAA) to remind them how important it is to safeguard their patients’ records. Physicians understand that patient information is sensitive and it would be disastrous if their files became public or fell into the wrong hands. However, the use of health information technology to record patient information, although beneficial for medical professionals and patients, poses risks to patient privacy.1
HIPAA requires clinicians and health care systems to protect patient information, whether it is maintained in an electronic health records system, stored on a mobile device, or transmitted via e-mail to another physician. The U.S. Department of Health and Human Services will increase HIPAA audits this year to make sure that medical practices have taken measures to protect their patients’ health information. Physicians and other clinicians can take advantage of cloud-based file-sharing services, such as Dropbox, without running afoul of HIPAA.
Mobile computing, the cloud, and patient information: A risky combination
Although mobile computing and cloud-based file-sharing sites such as Dropbox and Google Drive allow physicians to take notes on a tablet, annotate those notes on a laptop, and share them with a physician who views them on his (her) desktop, this free flow of information makes it more difficult to stay compliant with HIPAA.
Dropbox and other file-sharing services encrypt documents while they’re stored in the cloud but the files are unprotected when downloaded to a device. E-mail, which isn’t as versatile or useful as these services, also is not HIPAA-compliant unless the files are encrypted.
Often, small psychiatric practices use these online services and e-mail even if they’re aware of the risks because they don’t have time to research a better solution. Or they might resort to faxing or even snail-mailing documents, losing out on the increased productivity that the cloud can provide.
Secure technologies satisfy auditors
A number of tools exist to help physicians seamlessly integrate the encryption necessary to keep their patients’ records safe and meet HIPAA security requirements. Here’s a look at 3 options.
Sookasa (plus Dropbox). One option is to invest in a software product designed to encrypt documents shared through cloud-based services. This type of software creates a compliance “shield” around files stored on the cloud, converting files into HIPAA safe havens. The files are encrypted when synced to new devices or shared with other users, meaning they’re protected no matter where they reside.2
Sookasa is an online service that encrypts files shared and stored in Dropbox. The company plans to extend its support to other popular cloud services such as Google Drive and Microsoft OneDrive. Sookasa also audits and controls access to encrypted files, so that patient data can be blocked even if a device is lost or sto len. Sookasa users also can share files via e-mail with added encryption and authentication to make sure only the authorized receiver gets the documents.2
TigerText. Regular SMS text messages on your mobile phone aren’t compliant with HIPAA, but TigerText replicates the texting experience in a secure way. Instead of being stored on your mobile phone, messages sent through TigerText are stored on the company’s servers. Messages sent through the application can’t be saved, copied, or forwarded to other recipients. TigerText messages also are deleted, either after a set time period or after they’ve been read. Because the messages aren’t stored on phones, a lost or stolen phone won’t result in a data breach and a HIPAA violation.3
Secure text messaging won’t help physicians store and manage large amounts of patient files, but it’s a must-have if they use texting to communicate about patient care.
DataMotion SecureMail provides e-mail encryption services to health care organizations and other enterprises. Using a decryption key, authorized users can open and read the encrypted e-mails, which are HIPAA-compliant.4 This method is superior to other services that encrypt e-mails on the server. Several providers, such as Google’s e-mail encryption service Postini, ensure that e-mails are encrypted when they are stored on the server; however, the body text and attachments included in specific e-mails are not encrypted on the senders’ and receivers’ devices. If you lose a connected device, you would still be at risk of a HIPAA breach.
DataMotion’s SecureMail provides detailed tracking and logging of e-mails, which is necessary for auditing purposes. The product also works on mobile devices.
E-mail is a helpful tool for quickly sharing files and an e-mail encryption product such as SecureMail makes it possible to do so securely. Other e-mail encryption products do not securely store and back up all files in a centralized way.
DisclosureDr. Cidon is CEO and Co-founder of Sookasa.
Physicians hardly need the Health Insurance Portability and Accountability Act (HIPAA) to remind them how important it is to safeguard their patients’ records. Physicians understand that patient information is sensitive and it would be disastrous if their files became public or fell into the wrong hands. However, the use of health information technology to record patient information, although beneficial for medical professionals and patients, poses risks to patient privacy.1
HIPAA requires clinicians and health care systems to protect patient information, whether it is maintained in an electronic health records system, stored on a mobile device, or transmitted via e-mail to another physician. The U.S. Department of Health and Human Services will increase HIPAA audits this year to make sure that medical practices have taken measures to protect their patients’ health information. Physicians and other clinicians can take advantage of cloud-based file-sharing services, such as Dropbox, without running afoul of HIPAA.
Mobile computing, the cloud, and patient information: A risky combination
Although mobile computing and cloud-based file-sharing sites such as Dropbox and Google Drive allow physicians to take notes on a tablet, annotate those notes on a laptop, and share them with a physician who views them on his (her) desktop, this free flow of information makes it more difficult to stay compliant with HIPAA.
Dropbox and other file-sharing services encrypt documents while they’re stored in the cloud but the files are unprotected when downloaded to a device. E-mail, which isn’t as versatile or useful as these services, also is not HIPAA-compliant unless the files are encrypted.
Often, small psychiatric practices use these online services and e-mail even if they’re aware of the risks because they don’t have time to research a better solution. Or they might resort to faxing or even snail-mailing documents, losing out on the increased productivity that the cloud can provide.
Secure technologies satisfy auditors
A number of tools exist to help physicians seamlessly integrate the encryption necessary to keep their patients’ records safe and meet HIPAA security requirements. Here’s a look at 3 options.
Sookasa (plus Dropbox). One option is to invest in a software product designed to encrypt documents shared through cloud-based services. This type of software creates a compliance “shield” around files stored on the cloud, converting files into HIPAA safe havens. The files are encrypted when synced to new devices or shared with other users, meaning they’re protected no matter where they reside.2
Sookasa is an online service that encrypts files shared and stored in Dropbox. The company plans to extend its support to other popular cloud services such as Google Drive and Microsoft OneDrive. Sookasa also audits and controls access to encrypted files, so that patient data can be blocked even if a device is lost or sto len. Sookasa users also can share files via e-mail with added encryption and authentication to make sure only the authorized receiver gets the documents.2
TigerText. Regular SMS text messages on your mobile phone aren’t compliant with HIPAA, but TigerText replicates the texting experience in a secure way. Instead of being stored on your mobile phone, messages sent through TigerText are stored on the company’s servers. Messages sent through the application can’t be saved, copied, or forwarded to other recipients. TigerText messages also are deleted, either after a set time period or after they’ve been read. Because the messages aren’t stored on phones, a lost or stolen phone won’t result in a data breach and a HIPAA violation.3
Secure text messaging won’t help physicians store and manage large amounts of patient files, but it’s a must-have if they use texting to communicate about patient care.
DataMotion SecureMail provides e-mail encryption services to health care organizations and other enterprises. Using a decryption key, authorized users can open and read the encrypted e-mails, which are HIPAA-compliant.4 This method is superior to other services that encrypt e-mails on the server. Several providers, such as Google’s e-mail encryption service Postini, ensure that e-mails are encrypted when they are stored on the server; however, the body text and attachments included in specific e-mails are not encrypted on the senders’ and receivers’ devices. If you lose a connected device, you would still be at risk of a HIPAA breach.
DataMotion’s SecureMail provides detailed tracking and logging of e-mails, which is necessary for auditing purposes. The product also works on mobile devices.
E-mail is a helpful tool for quickly sharing files and an e-mail encryption product such as SecureMail makes it possible to do so securely. Other e-mail encryption products do not securely store and back up all files in a centralized way.
DisclosureDr. Cidon is CEO and Co-founder of Sookasa.
1. U.S. Department of Health and Human Services. HIPAA privacy, security, and breach notification adult program. http://www.hhs.gov/ocr/privacy/hipaa/enforcement/ audit. Accessed February 12, 2015.
2. Sookasa Web site. How it works. https://www.sookasa. com/how-it-works. Accessed February 12, 2015.
3. TigerText Web site. http://www.tigertext.com. Accessed February 12, 2015.
4. DataMotion Web site. http://datamotion.com/products/ securemail/securemail-desktop. Accessed February 12, 2015.
1. U.S. Department of Health and Human Services. HIPAA privacy, security, and breach notification adult program. http://www.hhs.gov/ocr/privacy/hipaa/enforcement/ audit. Accessed February 12, 2015.
2. Sookasa Web site. How it works. https://www.sookasa. com/how-it-works. Accessed February 12, 2015.
3. TigerText Web site. http://www.tigertext.com. Accessed February 12, 2015.
4. DataMotion Web site. http://datamotion.com/products/ securemail/securemail-desktop. Accessed February 12, 2015.
Abnormal calcium level in a psychiatric presentation? Rule out parathyroid disease
In some patients, symptoms of depression, psychosis, delirium, or dementia exist concomitantly with, or as a result of, an abnormal (elevated or low) serum calcium concentration that has been precipitated by an unrecognized endocrinopathy. The apparent psychiatric presentations of such patients might reflect parathyroid pathology—not psychopathology.
Hypercalcemia and hypocalcemia often are related to a distinct spectrum of conditions, such as diseases of the parathyroid glands, kidneys, and various neoplasms including malignancies. Be alert to the possibility of parathyroid disease in patients whose presentation suggests mental illness concurrent with, or as a direct consequence of, an abnormal calcium level, and investigate appropriately.
The Table1-9 illustrates how 3 clinical laboratory tests—serum calcium, serum parathyroid hormone (PTH), and phosphate—can narrow the differential diagnosis when the clinical impression is parathyroid-related illness. Seek endocrinology consultation whenever a parathyroid-associated ailment is discovered or suspected. Serum calcium is routinely assayed in hospitalized patients; when managing a patient with treatment-refractory psychiatric illness, (1) always check the reported result of that test and (2) consider measuring PTH.
Case reports1
Case 1: Woman with chronic depression. The patient was hospitalized while suicidal. Serial serum calcium levels were 12.5 mg/dL and 15.8 mg/dL (reference range, 8.2–10.2 mg/dL). The PTH level was elevated at 287 pg/mL (reference range, 10–65 pg/mL).
After thyroid imaging, surgery revealed a parathyroid mass, which was resected. Histologic examination confirmed an adenoma.
The calcium concentration declined to 8.6 mg/dL postoperatively and stabilized at 9.2 mg/dL. Psychiatric symptoms resolved fully; she experienced a complete recovery.
Case 2: Man on long-term lithium maintenance. The patient was admitted in a delusional psychotic state. The serum calcium level was 14.3 mg/dL initially, decreasing to 11.5 mg/dL after lithium was discontinued. The PTH level was elevated at 97 pg/mL at admission, consistent with hyperparathyroidism.
A parathyroid adenoma was resected. Serum calcium level normalized at 10.7 mg/dL; psychosis resolved with striking, sustained improvement in mental status.
Full return to mental, physical health
The diagnosis of parathyroid adenoma in these 2 patients, which began with a psychiatric presentation, was properly made after an abnormal serum calcium level was documented. Surgical treatment of the endocrinopathy produced full remission and a return to normal mental and physical health.
Although psychiatric manifestations are associated with an abnormal serum calcium concentration, the severity of those presentations does not correlate with the degree of abnormality of the calcium level.10
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Velasco PJ, Manshadi M, Breen K, et al. Psychiatric aspects of parathyroid disease. Psychosomatics. 1999;40(6):486-490.
2. Harrop JS, Bailey JE, Woodhead JS. Incidence of hypercalcaemia and primary hyperparathyroidism in relation to the biochemical profile. J Clin Pathol. 1982; 35(4):395-400.
3. Assadi F. Hypophosphatemia: an evidence-based problem-solving approach to clinical cases. Iran J Kidney Dis. 2010;4(3):195-201.
4. Ozkhan B, Hatun S, Bereket A. Vitamin D intoxication. Turk J Pediatr. 2012;54(2):93-98.
5. Studdy PR, Bird R, Neville E, et al. Biochemical findings in sarcoidosis. J Clin Pathol. 1980;33(6):528-533.
6. Geller JL, Adam JS. Vitamin D therapy. Curr Osteoporos Rep. 2008;6(1):5-11.
7. Albaaj F, Hutchison A. Hyperphosphatemia in renal failure: causes, consequences and current management. Drugs. 2003;63(6):577-596.
8. Al-Azem H, Khan AA. Hypoparathyroidism. Best Pract Res Clin Endocrinol Metab. 2012;26(4):517-522.
9. Brown H, Englert E, Wallach S. The syndrome of pseudo-pseudohypoparathyroidism. AMA Arch Intern Med. 1956;98(4):517-524.
10. Pfitzenmeyer P, Besancenot JF, Verges B, et al. Primary hyperparathyroidism in very old patients. Eur J Med. 1993;2(8):453-456.
In some patients, symptoms of depression, psychosis, delirium, or dementia exist concomitantly with, or as a result of, an abnormal (elevated or low) serum calcium concentration that has been precipitated by an unrecognized endocrinopathy. The apparent psychiatric presentations of such patients might reflect parathyroid pathology—not psychopathology.
Hypercalcemia and hypocalcemia often are related to a distinct spectrum of conditions, such as diseases of the parathyroid glands, kidneys, and various neoplasms including malignancies. Be alert to the possibility of parathyroid disease in patients whose presentation suggests mental illness concurrent with, or as a direct consequence of, an abnormal calcium level, and investigate appropriately.
The Table1-9 illustrates how 3 clinical laboratory tests—serum calcium, serum parathyroid hormone (PTH), and phosphate—can narrow the differential diagnosis when the clinical impression is parathyroid-related illness. Seek endocrinology consultation whenever a parathyroid-associated ailment is discovered or suspected. Serum calcium is routinely assayed in hospitalized patients; when managing a patient with treatment-refractory psychiatric illness, (1) always check the reported result of that test and (2) consider measuring PTH.
Case reports1
Case 1: Woman with chronic depression. The patient was hospitalized while suicidal. Serial serum calcium levels were 12.5 mg/dL and 15.8 mg/dL (reference range, 8.2–10.2 mg/dL). The PTH level was elevated at 287 pg/mL (reference range, 10–65 pg/mL).
After thyroid imaging, surgery revealed a parathyroid mass, which was resected. Histologic examination confirmed an adenoma.
The calcium concentration declined to 8.6 mg/dL postoperatively and stabilized at 9.2 mg/dL. Psychiatric symptoms resolved fully; she experienced a complete recovery.
Case 2: Man on long-term lithium maintenance. The patient was admitted in a delusional psychotic state. The serum calcium level was 14.3 mg/dL initially, decreasing to 11.5 mg/dL after lithium was discontinued. The PTH level was elevated at 97 pg/mL at admission, consistent with hyperparathyroidism.
A parathyroid adenoma was resected. Serum calcium level normalized at 10.7 mg/dL; psychosis resolved with striking, sustained improvement in mental status.
Full return to mental, physical health
The diagnosis of parathyroid adenoma in these 2 patients, which began with a psychiatric presentation, was properly made after an abnormal serum calcium level was documented. Surgical treatment of the endocrinopathy produced full remission and a return to normal mental and physical health.
Although psychiatric manifestations are associated with an abnormal serum calcium concentration, the severity of those presentations does not correlate with the degree of abnormality of the calcium level.10
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
In some patients, symptoms of depression, psychosis, delirium, or dementia exist concomitantly with, or as a result of, an abnormal (elevated or low) serum calcium concentration that has been precipitated by an unrecognized endocrinopathy. The apparent psychiatric presentations of such patients might reflect parathyroid pathology—not psychopathology.
Hypercalcemia and hypocalcemia often are related to a distinct spectrum of conditions, such as diseases of the parathyroid glands, kidneys, and various neoplasms including malignancies. Be alert to the possibility of parathyroid disease in patients whose presentation suggests mental illness concurrent with, or as a direct consequence of, an abnormal calcium level, and investigate appropriately.
The Table1-9 illustrates how 3 clinical laboratory tests—serum calcium, serum parathyroid hormone (PTH), and phosphate—can narrow the differential diagnosis when the clinical impression is parathyroid-related illness. Seek endocrinology consultation whenever a parathyroid-associated ailment is discovered or suspected. Serum calcium is routinely assayed in hospitalized patients; when managing a patient with treatment-refractory psychiatric illness, (1) always check the reported result of that test and (2) consider measuring PTH.
Case reports1
Case 1: Woman with chronic depression. The patient was hospitalized while suicidal. Serial serum calcium levels were 12.5 mg/dL and 15.8 mg/dL (reference range, 8.2–10.2 mg/dL). The PTH level was elevated at 287 pg/mL (reference range, 10–65 pg/mL).
After thyroid imaging, surgery revealed a parathyroid mass, which was resected. Histologic examination confirmed an adenoma.
The calcium concentration declined to 8.6 mg/dL postoperatively and stabilized at 9.2 mg/dL. Psychiatric symptoms resolved fully; she experienced a complete recovery.
Case 2: Man on long-term lithium maintenance. The patient was admitted in a delusional psychotic state. The serum calcium level was 14.3 mg/dL initially, decreasing to 11.5 mg/dL after lithium was discontinued. The PTH level was elevated at 97 pg/mL at admission, consistent with hyperparathyroidism.
A parathyroid adenoma was resected. Serum calcium level normalized at 10.7 mg/dL; psychosis resolved with striking, sustained improvement in mental status.
Full return to mental, physical health
The diagnosis of parathyroid adenoma in these 2 patients, which began with a psychiatric presentation, was properly made after an abnormal serum calcium level was documented. Surgical treatment of the endocrinopathy produced full remission and a return to normal mental and physical health.
Although psychiatric manifestations are associated with an abnormal serum calcium concentration, the severity of those presentations does not correlate with the degree of abnormality of the calcium level.10
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Velasco PJ, Manshadi M, Breen K, et al. Psychiatric aspects of parathyroid disease. Psychosomatics. 1999;40(6):486-490.
2. Harrop JS, Bailey JE, Woodhead JS. Incidence of hypercalcaemia and primary hyperparathyroidism in relation to the biochemical profile. J Clin Pathol. 1982; 35(4):395-400.
3. Assadi F. Hypophosphatemia: an evidence-based problem-solving approach to clinical cases. Iran J Kidney Dis. 2010;4(3):195-201.
4. Ozkhan B, Hatun S, Bereket A. Vitamin D intoxication. Turk J Pediatr. 2012;54(2):93-98.
5. Studdy PR, Bird R, Neville E, et al. Biochemical findings in sarcoidosis. J Clin Pathol. 1980;33(6):528-533.
6. Geller JL, Adam JS. Vitamin D therapy. Curr Osteoporos Rep. 2008;6(1):5-11.
7. Albaaj F, Hutchison A. Hyperphosphatemia in renal failure: causes, consequences and current management. Drugs. 2003;63(6):577-596.
8. Al-Azem H, Khan AA. Hypoparathyroidism. Best Pract Res Clin Endocrinol Metab. 2012;26(4):517-522.
9. Brown H, Englert E, Wallach S. The syndrome of pseudo-pseudohypoparathyroidism. AMA Arch Intern Med. 1956;98(4):517-524.
10. Pfitzenmeyer P, Besancenot JF, Verges B, et al. Primary hyperparathyroidism in very old patients. Eur J Med. 1993;2(8):453-456.
1. Velasco PJ, Manshadi M, Breen K, et al. Psychiatric aspects of parathyroid disease. Psychosomatics. 1999;40(6):486-490.
2. Harrop JS, Bailey JE, Woodhead JS. Incidence of hypercalcaemia and primary hyperparathyroidism in relation to the biochemical profile. J Clin Pathol. 1982; 35(4):395-400.
3. Assadi F. Hypophosphatemia: an evidence-based problem-solving approach to clinical cases. Iran J Kidney Dis. 2010;4(3):195-201.
4. Ozkhan B, Hatun S, Bereket A. Vitamin D intoxication. Turk J Pediatr. 2012;54(2):93-98.
5. Studdy PR, Bird R, Neville E, et al. Biochemical findings in sarcoidosis. J Clin Pathol. 1980;33(6):528-533.
6. Geller JL, Adam JS. Vitamin D therapy. Curr Osteoporos Rep. 2008;6(1):5-11.
7. Albaaj F, Hutchison A. Hyperphosphatemia in renal failure: causes, consequences and current management. Drugs. 2003;63(6):577-596.
8. Al-Azem H, Khan AA. Hypoparathyroidism. Best Pract Res Clin Endocrinol Metab. 2012;26(4):517-522.
9. Brown H, Englert E, Wallach S. The syndrome of pseudo-pseudohypoparathyroidism. AMA Arch Intern Med. 1956;98(4):517-524.
10. Pfitzenmeyer P, Besancenot JF, Verges B, et al. Primary hyperparathyroidism in very old patients. Eur J Med. 1993;2(8):453-456.
How to write a suicide risk assessment that’s clinically sound and legally defensible
Suicidologists and legal experts implore clinicians to document their suicide risk assessments (SRAs) thoroughly. It’s difficult, however, to find practical guidance on how to write a clinically sound, legally defensible SRA.
The crux of every SRA is written justification of suicide risk. That justification should reveal your thinking and present a well-reasoned basis for your decision.
Reasoned vs right
It’s more important to provide a justification of suicide risk that’s well-reasoned rather than one that’s right. Suicide is impossible to predict. Instead of prediction, legally we are asked to reasonably anticipate suicide based on clinical facts. In hindsight, especially in the context of a courtroom, decisions might look ill-considered. You need to craft a logical argument, be clear, and avoid jargon.
Convey thoroughness by covering each component of an SRA. Use the mnemonic device CAIPS to help the reader (and you) understand how a conclusion was reached based on the facts of the case.
Chronic and Acute factors. Address the chronic and acute factors that weigh heaviest in your mind. Chronic factors are conditions, past events, and demographics that generally do not change. Acute factors are recent events or conditions that potentially are modifiable. Pay attention to combinations of factors that dramatically elevate risk (eg, previous attempts in the context of acute depression). Avoid repeating every factor, especially when these are documented elsewhere, such as on a checklist.
Imminent warning signs for suicide. Address warning signs (Table 1),1 the nature of current suicidal thoughts (Table 2), and other aspects of mental status (eg, future orientation) that influenced your decision. Use words like “moreover,” “however,” and “in addition” to draw the reader’s attention to the building blocks of your argument.
Protective factors. Discuss the protective factors last; they deserve the least weight because none has been shown to immunize people against suicide. Don’t solely rely on your judgment of what is protective (eg, children in the home). Instead, elicit the patient’s reasons for living and dying. Be concerned if he (she) reports more of the latter.
Summary statement. Make an explicit statement about risk, focusing on imminent risk (ie, the next few hours and days). Avoid a “plot twist,” which is a risk level inconsistent with the preceding evidence, because it suggests an error in judgment. The Box gives an example of a justification that follows the CAIPS method.
Additional tips
Consider these strategies:
• Bolster your argument by explicitly addressing hopelessness (the strongest psychological correlate of suicide); use quotes from the patient that support your decision; refer to consultation with family members and colleagues; and include pertinent negatives to show completeness2 (ie, “denied suicide plans”).
• Critically resolve discrepancies between what the patient says and behavior that suggests suicidal intent (eg, a patient who minimizes suicidal intent but shopped for a gun yesterday).
• Last, while reviewing your justification, imagine that your patient completed suicide after leaving your office and that you are in court for negligence. In our experience, this exercise reveals dangerous errors of judgment. A clear and reasoned justification will reduce the risk of litigation and help you make prudent treatment plans.
Disclosures
The authors report no financial relationships with any companies whose products are mentioned in this article or with manufacturers of competing products.
1. American Association of Suicidology. Know the warning signs of suicide. http://www.suicidology.org/resources/ warning-signs. Accessed February 9, 2014.
2. Ballas C. How to write a suicide note: practical tips for documenting the evaluation of a suicidal patient. Psychiatric Times. http://www.psychiatrictimes.com/articles/how-write-suicide-note-practical-tips-documenting-evaluation-suicidal-patient. Published May 1, 2007. Accessed July 29, 2013.
Suicidologists and legal experts implore clinicians to document their suicide risk assessments (SRAs) thoroughly. It’s difficult, however, to find practical guidance on how to write a clinically sound, legally defensible SRA.
The crux of every SRA is written justification of suicide risk. That justification should reveal your thinking and present a well-reasoned basis for your decision.
Reasoned vs right
It’s more important to provide a justification of suicide risk that’s well-reasoned rather than one that’s right. Suicide is impossible to predict. Instead of prediction, legally we are asked to reasonably anticipate suicide based on clinical facts. In hindsight, especially in the context of a courtroom, decisions might look ill-considered. You need to craft a logical argument, be clear, and avoid jargon.
Convey thoroughness by covering each component of an SRA. Use the mnemonic device CAIPS to help the reader (and you) understand how a conclusion was reached based on the facts of the case.
Chronic and Acute factors. Address the chronic and acute factors that weigh heaviest in your mind. Chronic factors are conditions, past events, and demographics that generally do not change. Acute factors are recent events or conditions that potentially are modifiable. Pay attention to combinations of factors that dramatically elevate risk (eg, previous attempts in the context of acute depression). Avoid repeating every factor, especially when these are documented elsewhere, such as on a checklist.
Imminent warning signs for suicide. Address warning signs (Table 1),1 the nature of current suicidal thoughts (Table 2), and other aspects of mental status (eg, future orientation) that influenced your decision. Use words like “moreover,” “however,” and “in addition” to draw the reader’s attention to the building blocks of your argument.
Protective factors. Discuss the protective factors last; they deserve the least weight because none has been shown to immunize people against suicide. Don’t solely rely on your judgment of what is protective (eg, children in the home). Instead, elicit the patient’s reasons for living and dying. Be concerned if he (she) reports more of the latter.
Summary statement. Make an explicit statement about risk, focusing on imminent risk (ie, the next few hours and days). Avoid a “plot twist,” which is a risk level inconsistent with the preceding evidence, because it suggests an error in judgment. The Box gives an example of a justification that follows the CAIPS method.
Additional tips
Consider these strategies:
• Bolster your argument by explicitly addressing hopelessness (the strongest psychological correlate of suicide); use quotes from the patient that support your decision; refer to consultation with family members and colleagues; and include pertinent negatives to show completeness2 (ie, “denied suicide plans”).
• Critically resolve discrepancies between what the patient says and behavior that suggests suicidal intent (eg, a patient who minimizes suicidal intent but shopped for a gun yesterday).
• Last, while reviewing your justification, imagine that your patient completed suicide after leaving your office and that you are in court for negligence. In our experience, this exercise reveals dangerous errors of judgment. A clear and reasoned justification will reduce the risk of litigation and help you make prudent treatment plans.
Disclosures
The authors report no financial relationships with any companies whose products are mentioned in this article or with manufacturers of competing products.
Suicidologists and legal experts implore clinicians to document their suicide risk assessments (SRAs) thoroughly. It’s difficult, however, to find practical guidance on how to write a clinically sound, legally defensible SRA.
The crux of every SRA is written justification of suicide risk. That justification should reveal your thinking and present a well-reasoned basis for your decision.
Reasoned vs right
It’s more important to provide a justification of suicide risk that’s well-reasoned rather than one that’s right. Suicide is impossible to predict. Instead of prediction, legally we are asked to reasonably anticipate suicide based on clinical facts. In hindsight, especially in the context of a courtroom, decisions might look ill-considered. You need to craft a logical argument, be clear, and avoid jargon.
Convey thoroughness by covering each component of an SRA. Use the mnemonic device CAIPS to help the reader (and you) understand how a conclusion was reached based on the facts of the case.
Chronic and Acute factors. Address the chronic and acute factors that weigh heaviest in your mind. Chronic factors are conditions, past events, and demographics that generally do not change. Acute factors are recent events or conditions that potentially are modifiable. Pay attention to combinations of factors that dramatically elevate risk (eg, previous attempts in the context of acute depression). Avoid repeating every factor, especially when these are documented elsewhere, such as on a checklist.
Imminent warning signs for suicide. Address warning signs (Table 1),1 the nature of current suicidal thoughts (Table 2), and other aspects of mental status (eg, future orientation) that influenced your decision. Use words like “moreover,” “however,” and “in addition” to draw the reader’s attention to the building blocks of your argument.
Protective factors. Discuss the protective factors last; they deserve the least weight because none has been shown to immunize people against suicide. Don’t solely rely on your judgment of what is protective (eg, children in the home). Instead, elicit the patient’s reasons for living and dying. Be concerned if he (she) reports more of the latter.
Summary statement. Make an explicit statement about risk, focusing on imminent risk (ie, the next few hours and days). Avoid a “plot twist,” which is a risk level inconsistent with the preceding evidence, because it suggests an error in judgment. The Box gives an example of a justification that follows the CAIPS method.
Additional tips
Consider these strategies:
• Bolster your argument by explicitly addressing hopelessness (the strongest psychological correlate of suicide); use quotes from the patient that support your decision; refer to consultation with family members and colleagues; and include pertinent negatives to show completeness2 (ie, “denied suicide plans”).
• Critically resolve discrepancies between what the patient says and behavior that suggests suicidal intent (eg, a patient who minimizes suicidal intent but shopped for a gun yesterday).
• Last, while reviewing your justification, imagine that your patient completed suicide after leaving your office and that you are in court for negligence. In our experience, this exercise reveals dangerous errors of judgment. A clear and reasoned justification will reduce the risk of litigation and help you make prudent treatment plans.
Disclosures
The authors report no financial relationships with any companies whose products are mentioned in this article or with manufacturers of competing products.
1. American Association of Suicidology. Know the warning signs of suicide. http://www.suicidology.org/resources/ warning-signs. Accessed February 9, 2014.
2. Ballas C. How to write a suicide note: practical tips for documenting the evaluation of a suicidal patient. Psychiatric Times. http://www.psychiatrictimes.com/articles/how-write-suicide-note-practical-tips-documenting-evaluation-suicidal-patient. Published May 1, 2007. Accessed July 29, 2013.
1. American Association of Suicidology. Know the warning signs of suicide. http://www.suicidology.org/resources/ warning-signs. Accessed February 9, 2014.
2. Ballas C. How to write a suicide note: practical tips for documenting the evaluation of a suicidal patient. Psychiatric Times. http://www.psychiatrictimes.com/articles/how-write-suicide-note-practical-tips-documenting-evaluation-suicidal-patient. Published May 1, 2007. Accessed July 29, 2013.
6 Strategies to address risk factors for school violence
School shootings engender the deepest of public concern. They violate strongly held cross-culture beliefs about the sanctity of childhood and the obligation to protect children from harm.
Prevention and intervention approaches to school shootings have emerged (1) in the literature, from case studies, and (2) from discourse among experts.1 Approaches include:
• bolstering security at schools
• reducing the facilities’ vulnerability to intrusion
• increasing the capacity to respond at the moment of threat
• transforming the school climate
• increasing attachment and bonding.1,2
Psychiatrists often are consulted by school districts to provide expertise for the latter 2 approaches. Using the following strategies, you can help address risk factors for school violence.
Strengthen school attachment. Develop curricular and extracurricular programs for students that create, and contribute to, a sense of belonging. This, in turn, decreases alienation and reduces hostility. Unaddressed hostility can lead to depression, anger, and, subsequently, violence.
Reduce social aggression. Social aggression, such as teasing, taunting, humiliating, and bullying, is an important predictor of developmental outcomes in victims and perpetrators.3 Social aggression has been linked to peer victimization and low school attachment. Implement social skills programs, such as Making Choices, which have yielded positive effects on social aggression in elementary school students.4
Break codes of silence. This can involve encouraging schools to:
• develop an anonymous mechanism of voicing concerns
• take diligent action based on students’ concerns
• treat disclosures discreetly.
Establish resources for troubled and rejected students. Develop routine emergency modes of communication, such as a protocol for high-priority referral to mental health resources. These could reduce the likelihood of students acting out against the school.
Recommend that security be enhanced. Establishing the position of school resource officer might increase confidence and decrease feelings of vulnerability among teachers, students, and parents. This can increase the perception of school security, potentially helps school attachment, and promotes breaking down codes of silence.5
Increase communication within the school, and between the school and law enforcement agencies. Effective communication can help identify the location of an attacker and disrupt a developing event. Create an alert system to notify students, faculty, and parents with an automated text message or phone call during an emergency. Increased accessibility of the students by the school alert system might be a quicker way to reach the school community. Work with security agencies to develop a protocol for communicating and assessing threat potential. Also, develop guidelines to outline referral and assessing procedures for students whose writings may present indication for possible attack or whose class behavior may be alienating or intimidating to either faculty or other students. Behavior that can lead to school violence is outlined in the Table.
You also can educate school administrators about the following:
• School violence has been significantly associated with mental health problems, such as depression and inability to form age appropriate social connections,6 which in combination with extreme social rejection and specific personality-related issues (eg, antisocial personality disorder) can culminate in violent outbreaks.7 Work closely with school nurses and counselors to identify and treat vulnerable students.
• In most multiple-victim incidents, more than 1 person had information about the attack before it occurred that was not communicated to an authority figure. Educate school officials about being sensitive to warnings or threats about possible attack, and help develop ways get counseling for potential attackers.2
• Zero-tolerance policies are ineffective at preventing school shootings, mostly because of literal interpretation and inconsistent implementation of such policies.8 Help circumvent a more stringent zero-tolerance policy with adequate availability of mental health care for students who are identified as being at risk of perpetrating an attack.
Disclosure
The author reports no financial relationship with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Culley MR, Conkling M, Emshoff J, et al. Environmental and contextual influences on school violence and its prevention. J Prim Prev. 2006;27(3):217-227.
2. Wike TL, Fraser MW. School shooting: making sense of the senseless. Aggress Violent Behav. 2009;14(3):162-169.
3. Rudatsikira E, Singh P, Job J, et al. Variables associated with weapon-carrying among young adolescents in southern California. J Adolesc Health. 2007;40(5):470-473.
4. Fraser MW, Galinsky MJ, Smokowski PR, et al. Social information-processing skills training to promote social competence and prevent aggressive behavior in the third grades. J Consult Clin Psychol. 2005;73(6):1045-1055.
5. Finn P. School resource officer programs. Finding the funding, reaping the benefits. FBI Law Enforcement Bulletin. 2006;75(8):1-13.
6. Ferguson C, Coulson M, Barnett J. Psychological profiles of school shooters: positive directions and one big wrong turn. J Police Crisis Negot. 2011;11:1-17.
7. Leary MR, Kowalski RM, Smith L, et al. Teasing, rejection and violence: case studies of the school shootings. Aggressive Behavior. 2003;29(3):202-214.
8. American Psychological Association Zero Tolerance Task Force. Are zero tolerance policies effective in the schools?: an evidentiary review and recommendation. Am Psychol. 2008;63(9):852-862.
School shootings engender the deepest of public concern. They violate strongly held cross-culture beliefs about the sanctity of childhood and the obligation to protect children from harm.
Prevention and intervention approaches to school shootings have emerged (1) in the literature, from case studies, and (2) from discourse among experts.1 Approaches include:
• bolstering security at schools
• reducing the facilities’ vulnerability to intrusion
• increasing the capacity to respond at the moment of threat
• transforming the school climate
• increasing attachment and bonding.1,2
Psychiatrists often are consulted by school districts to provide expertise for the latter 2 approaches. Using the following strategies, you can help address risk factors for school violence.
Strengthen school attachment. Develop curricular and extracurricular programs for students that create, and contribute to, a sense of belonging. This, in turn, decreases alienation and reduces hostility. Unaddressed hostility can lead to depression, anger, and, subsequently, violence.
Reduce social aggression. Social aggression, such as teasing, taunting, humiliating, and bullying, is an important predictor of developmental outcomes in victims and perpetrators.3 Social aggression has been linked to peer victimization and low school attachment. Implement social skills programs, such as Making Choices, which have yielded positive effects on social aggression in elementary school students.4
Break codes of silence. This can involve encouraging schools to:
• develop an anonymous mechanism of voicing concerns
• take diligent action based on students’ concerns
• treat disclosures discreetly.
Establish resources for troubled and rejected students. Develop routine emergency modes of communication, such as a protocol for high-priority referral to mental health resources. These could reduce the likelihood of students acting out against the school.
Recommend that security be enhanced. Establishing the position of school resource officer might increase confidence and decrease feelings of vulnerability among teachers, students, and parents. This can increase the perception of school security, potentially helps school attachment, and promotes breaking down codes of silence.5
Increase communication within the school, and between the school and law enforcement agencies. Effective communication can help identify the location of an attacker and disrupt a developing event. Create an alert system to notify students, faculty, and parents with an automated text message or phone call during an emergency. Increased accessibility of the students by the school alert system might be a quicker way to reach the school community. Work with security agencies to develop a protocol for communicating and assessing threat potential. Also, develop guidelines to outline referral and assessing procedures for students whose writings may present indication for possible attack or whose class behavior may be alienating or intimidating to either faculty or other students. Behavior that can lead to school violence is outlined in the Table.
You also can educate school administrators about the following:
• School violence has been significantly associated with mental health problems, such as depression and inability to form age appropriate social connections,6 which in combination with extreme social rejection and specific personality-related issues (eg, antisocial personality disorder) can culminate in violent outbreaks.7 Work closely with school nurses and counselors to identify and treat vulnerable students.
• In most multiple-victim incidents, more than 1 person had information about the attack before it occurred that was not communicated to an authority figure. Educate school officials about being sensitive to warnings or threats about possible attack, and help develop ways get counseling for potential attackers.2
• Zero-tolerance policies are ineffective at preventing school shootings, mostly because of literal interpretation and inconsistent implementation of such policies.8 Help circumvent a more stringent zero-tolerance policy with adequate availability of mental health care for students who are identified as being at risk of perpetrating an attack.
Disclosure
The author reports no financial relationship with any company whose products are mentioned in this article or with manufacturers of competing products.
School shootings engender the deepest of public concern. They violate strongly held cross-culture beliefs about the sanctity of childhood and the obligation to protect children from harm.
Prevention and intervention approaches to school shootings have emerged (1) in the literature, from case studies, and (2) from discourse among experts.1 Approaches include:
• bolstering security at schools
• reducing the facilities’ vulnerability to intrusion
• increasing the capacity to respond at the moment of threat
• transforming the school climate
• increasing attachment and bonding.1,2
Psychiatrists often are consulted by school districts to provide expertise for the latter 2 approaches. Using the following strategies, you can help address risk factors for school violence.
Strengthen school attachment. Develop curricular and extracurricular programs for students that create, and contribute to, a sense of belonging. This, in turn, decreases alienation and reduces hostility. Unaddressed hostility can lead to depression, anger, and, subsequently, violence.
Reduce social aggression. Social aggression, such as teasing, taunting, humiliating, and bullying, is an important predictor of developmental outcomes in victims and perpetrators.3 Social aggression has been linked to peer victimization and low school attachment. Implement social skills programs, such as Making Choices, which have yielded positive effects on social aggression in elementary school students.4
Break codes of silence. This can involve encouraging schools to:
• develop an anonymous mechanism of voicing concerns
• take diligent action based on students’ concerns
• treat disclosures discreetly.
Establish resources for troubled and rejected students. Develop routine emergency modes of communication, such as a protocol for high-priority referral to mental health resources. These could reduce the likelihood of students acting out against the school.
Recommend that security be enhanced. Establishing the position of school resource officer might increase confidence and decrease feelings of vulnerability among teachers, students, and parents. This can increase the perception of school security, potentially helps school attachment, and promotes breaking down codes of silence.5
Increase communication within the school, and between the school and law enforcement agencies. Effective communication can help identify the location of an attacker and disrupt a developing event. Create an alert system to notify students, faculty, and parents with an automated text message or phone call during an emergency. Increased accessibility of the students by the school alert system might be a quicker way to reach the school community. Work with security agencies to develop a protocol for communicating and assessing threat potential. Also, develop guidelines to outline referral and assessing procedures for students whose writings may present indication for possible attack or whose class behavior may be alienating or intimidating to either faculty or other students. Behavior that can lead to school violence is outlined in the Table.
You also can educate school administrators about the following:
• School violence has been significantly associated with mental health problems, such as depression and inability to form age appropriate social connections,6 which in combination with extreme social rejection and specific personality-related issues (eg, antisocial personality disorder) can culminate in violent outbreaks.7 Work closely with school nurses and counselors to identify and treat vulnerable students.
• In most multiple-victim incidents, more than 1 person had information about the attack before it occurred that was not communicated to an authority figure. Educate school officials about being sensitive to warnings or threats about possible attack, and help develop ways get counseling for potential attackers.2
• Zero-tolerance policies are ineffective at preventing school shootings, mostly because of literal interpretation and inconsistent implementation of such policies.8 Help circumvent a more stringent zero-tolerance policy with adequate availability of mental health care for students who are identified as being at risk of perpetrating an attack.
Disclosure
The author reports no financial relationship with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Culley MR, Conkling M, Emshoff J, et al. Environmental and contextual influences on school violence and its prevention. J Prim Prev. 2006;27(3):217-227.
2. Wike TL, Fraser MW. School shooting: making sense of the senseless. Aggress Violent Behav. 2009;14(3):162-169.
3. Rudatsikira E, Singh P, Job J, et al. Variables associated with weapon-carrying among young adolescents in southern California. J Adolesc Health. 2007;40(5):470-473.
4. Fraser MW, Galinsky MJ, Smokowski PR, et al. Social information-processing skills training to promote social competence and prevent aggressive behavior in the third grades. J Consult Clin Psychol. 2005;73(6):1045-1055.
5. Finn P. School resource officer programs. Finding the funding, reaping the benefits. FBI Law Enforcement Bulletin. 2006;75(8):1-13.
6. Ferguson C, Coulson M, Barnett J. Psychological profiles of school shooters: positive directions and one big wrong turn. J Police Crisis Negot. 2011;11:1-17.
7. Leary MR, Kowalski RM, Smith L, et al. Teasing, rejection and violence: case studies of the school shootings. Aggressive Behavior. 2003;29(3):202-214.
8. American Psychological Association Zero Tolerance Task Force. Are zero tolerance policies effective in the schools?: an evidentiary review and recommendation. Am Psychol. 2008;63(9):852-862.
1. Culley MR, Conkling M, Emshoff J, et al. Environmental and contextual influences on school violence and its prevention. J Prim Prev. 2006;27(3):217-227.
2. Wike TL, Fraser MW. School shooting: making sense of the senseless. Aggress Violent Behav. 2009;14(3):162-169.
3. Rudatsikira E, Singh P, Job J, et al. Variables associated with weapon-carrying among young adolescents in southern California. J Adolesc Health. 2007;40(5):470-473.
4. Fraser MW, Galinsky MJ, Smokowski PR, et al. Social information-processing skills training to promote social competence and prevent aggressive behavior in the third grades. J Consult Clin Psychol. 2005;73(6):1045-1055.
5. Finn P. School resource officer programs. Finding the funding, reaping the benefits. FBI Law Enforcement Bulletin. 2006;75(8):1-13.
6. Ferguson C, Coulson M, Barnett J. Psychological profiles of school shooters: positive directions and one big wrong turn. J Police Crisis Negot. 2011;11:1-17.
7. Leary MR, Kowalski RM, Smith L, et al. Teasing, rejection and violence: case studies of the school shootings. Aggressive Behavior. 2003;29(3):202-214.
8. American Psychological Association Zero Tolerance Task Force. Are zero tolerance policies effective in the schools?: an evidentiary review and recommendation. Am Psychol. 2008;63(9):852-862.
‘No SAD Me’: A memory device for treating bipolar depression with an antidepressant
Depression is the first affective episode in >50% of patients with bipolar disorder, and is associated with considerable morbidity and mortality.
The mean duration of a bipolar depressive episode is considerably longer than a manic episode; >20% of bipolar depressive episodes run a chronic course.1 Evidence suggests that depressive episodes and symptoms are equal to, or more disabling than, corresponding levels of manic or hypomanic symptoms.2
Debate over appropriate therapy
Using antidepressants to treat bipolar depression remains controversial. Much of the debate surrounds concern that antidepressants have the potential to switch a patient to mania/hypomania or to destabilize mood over the longitudinal course of illness.2
Several guidelines for informing the use of antidepressants in bipolar depression have been published, including the International Society for Bipolar Disorders task force report on antidepressant use in bipolar disorders3 and the guideline of the World Federation of Societies of Biological Psychiatry.4 To summarize the most recent consensus on treating bipolar depression, we devised the mnemonic No SAD Me:
No n-antidepressant treatments should be considered as monotherapy before antidepressants are used. Consider lithium, lamotrigine, olanzapine, quetiapine, or lurasidone first for bipolar depression.3
S afe-to-use adjunctive antidepressants can be considered if the patient relapses to a depressive episode after antidepressant therapy is stopped. Consider using a selective serotonin reuptake inhibitor (SSRI) and bupropion (1) for an acute bipolar I or II depressive episode when the patient has a history of a positive response to an antidepressant and (2) as maintenance treatment with SSRIs and bupropion as adjunctive therapy.2,3
A void antidepressants as monotherapy. If using an antidepressant to treat bipolar I disorder, prescribe a mood-stabilizer concomitantly, even though the evidence for antidepressant-associated mood-switching is mixed and the ability of mood stabilizers to prevent such responses to antidepressant treatment is unproven.
D o not use tricyclic antidepressants (TCAs) or venlafaxine. Evidence does not show 1 type of antidepressant is more or less effective or dangerous than another. Nevertheless, TCAs and venlafaxine appear to carry a particularly high risk of inducing pathologically elevated states of mood and behavior.3
M onitor closely. Bipolar disorder patients who are being started on an antidepressant should be closely monitored for signs of hypomania or mania and increased psychomotor agitation. Discontinue the antidepressant if such signs are observed or emerge.
Disclosures
The authors report no financial relationship with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Sidor MM, MacQueen GM. An update on antidepressant use in bipolar depression. Curr Psychiatry Rep. 2012;14(6):696-704.
2. Pacchiarotti I, Mazzarini L, Colom F, et al. Treatment-resistant bipolar depression: towards a new definition. Acta Psychiatr Scand. 2009;120(6):429-440.
3. Pacchiarotti I, Bond DJ, Baldessarini RJ, et al. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry. 2013; 170(11):1249-1262.
4. Grunze H, Vieta E, Goodwin GM, et al; WFSBP Task Force On Treatment Guidelines For Bipolar Disorders. The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression. World J Biol Psychiatry. 2010;11:81-109.
Depression is the first affective episode in >50% of patients with bipolar disorder, and is associated with considerable morbidity and mortality.
The mean duration of a bipolar depressive episode is considerably longer than a manic episode; >20% of bipolar depressive episodes run a chronic course.1 Evidence suggests that depressive episodes and symptoms are equal to, or more disabling than, corresponding levels of manic or hypomanic symptoms.2
Debate over appropriate therapy
Using antidepressants to treat bipolar depression remains controversial. Much of the debate surrounds concern that antidepressants have the potential to switch a patient to mania/hypomania or to destabilize mood over the longitudinal course of illness.2
Several guidelines for informing the use of antidepressants in bipolar depression have been published, including the International Society for Bipolar Disorders task force report on antidepressant use in bipolar disorders3 and the guideline of the World Federation of Societies of Biological Psychiatry.4 To summarize the most recent consensus on treating bipolar depression, we devised the mnemonic No SAD Me:
No n-antidepressant treatments should be considered as monotherapy before antidepressants are used. Consider lithium, lamotrigine, olanzapine, quetiapine, or lurasidone first for bipolar depression.3
S afe-to-use adjunctive antidepressants can be considered if the patient relapses to a depressive episode after antidepressant therapy is stopped. Consider using a selective serotonin reuptake inhibitor (SSRI) and bupropion (1) for an acute bipolar I or II depressive episode when the patient has a history of a positive response to an antidepressant and (2) as maintenance treatment with SSRIs and bupropion as adjunctive therapy.2,3
A void antidepressants as monotherapy. If using an antidepressant to treat bipolar I disorder, prescribe a mood-stabilizer concomitantly, even though the evidence for antidepressant-associated mood-switching is mixed and the ability of mood stabilizers to prevent such responses to antidepressant treatment is unproven.
D o not use tricyclic antidepressants (TCAs) or venlafaxine. Evidence does not show 1 type of antidepressant is more or less effective or dangerous than another. Nevertheless, TCAs and venlafaxine appear to carry a particularly high risk of inducing pathologically elevated states of mood and behavior.3
M onitor closely. Bipolar disorder patients who are being started on an antidepressant should be closely monitored for signs of hypomania or mania and increased psychomotor agitation. Discontinue the antidepressant if such signs are observed or emerge.
Disclosures
The authors report no financial relationship with any company whose products are mentioned in this article or with manufacturers of competing products.
Depression is the first affective episode in >50% of patients with bipolar disorder, and is associated with considerable morbidity and mortality.
The mean duration of a bipolar depressive episode is considerably longer than a manic episode; >20% of bipolar depressive episodes run a chronic course.1 Evidence suggests that depressive episodes and symptoms are equal to, or more disabling than, corresponding levels of manic or hypomanic symptoms.2
Debate over appropriate therapy
Using antidepressants to treat bipolar depression remains controversial. Much of the debate surrounds concern that antidepressants have the potential to switch a patient to mania/hypomania or to destabilize mood over the longitudinal course of illness.2
Several guidelines for informing the use of antidepressants in bipolar depression have been published, including the International Society for Bipolar Disorders task force report on antidepressant use in bipolar disorders3 and the guideline of the World Federation of Societies of Biological Psychiatry.4 To summarize the most recent consensus on treating bipolar depression, we devised the mnemonic No SAD Me:
No n-antidepressant treatments should be considered as monotherapy before antidepressants are used. Consider lithium, lamotrigine, olanzapine, quetiapine, or lurasidone first for bipolar depression.3
S afe-to-use adjunctive antidepressants can be considered if the patient relapses to a depressive episode after antidepressant therapy is stopped. Consider using a selective serotonin reuptake inhibitor (SSRI) and bupropion (1) for an acute bipolar I or II depressive episode when the patient has a history of a positive response to an antidepressant and (2) as maintenance treatment with SSRIs and bupropion as adjunctive therapy.2,3
A void antidepressants as monotherapy. If using an antidepressant to treat bipolar I disorder, prescribe a mood-stabilizer concomitantly, even though the evidence for antidepressant-associated mood-switching is mixed and the ability of mood stabilizers to prevent such responses to antidepressant treatment is unproven.
D o not use tricyclic antidepressants (TCAs) or venlafaxine. Evidence does not show 1 type of antidepressant is more or less effective or dangerous than another. Nevertheless, TCAs and venlafaxine appear to carry a particularly high risk of inducing pathologically elevated states of mood and behavior.3
M onitor closely. Bipolar disorder patients who are being started on an antidepressant should be closely monitored for signs of hypomania or mania and increased psychomotor agitation. Discontinue the antidepressant if such signs are observed or emerge.
Disclosures
The authors report no financial relationship with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Sidor MM, MacQueen GM. An update on antidepressant use in bipolar depression. Curr Psychiatry Rep. 2012;14(6):696-704.
2. Pacchiarotti I, Mazzarini L, Colom F, et al. Treatment-resistant bipolar depression: towards a new definition. Acta Psychiatr Scand. 2009;120(6):429-440.
3. Pacchiarotti I, Bond DJ, Baldessarini RJ, et al. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry. 2013; 170(11):1249-1262.
4. Grunze H, Vieta E, Goodwin GM, et al; WFSBP Task Force On Treatment Guidelines For Bipolar Disorders. The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression. World J Biol Psychiatry. 2010;11:81-109.
1. Sidor MM, MacQueen GM. An update on antidepressant use in bipolar depression. Curr Psychiatry Rep. 2012;14(6):696-704.
2. Pacchiarotti I, Mazzarini L, Colom F, et al. Treatment-resistant bipolar depression: towards a new definition. Acta Psychiatr Scand. 2009;120(6):429-440.
3. Pacchiarotti I, Bond DJ, Baldessarini RJ, et al. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry. 2013; 170(11):1249-1262.
4. Grunze H, Vieta E, Goodwin GM, et al; WFSBP Task Force On Treatment Guidelines For Bipolar Disorders. The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression. World J Biol Psychiatry. 2010;11:81-109.
Consider a mandibular positioning device to alleviate sleep-disordered breathing
Snoring, snorting, gasping, and obstructive sleep apnea are caused by collapse of the pharyngeal airway during sleep.1 Pathophysiology includes a combination of anatomical and physiological variables.1 Common anatomical predisposing conditions include abnormalities of pharyngeal, lingual, and dental arches; physiological concerns are advancing age, male sex, obesity, use of sedatives, body positioning, and reduced muscle tone during rapid eye movement sleep. Coexistence of anatomic and physiological elements can produce significant narrowing of the upper airway.
Comorbidities include vascular, metabolic, and psychiatric conditions. As many as one-third of people with symptoms of sleep apnea report depressed mood; approximately 10% of these patients meet criteria for moderate or severe depression.2
In short, sleep-disordered breathing has a globally negative effect on mental health.
When should you consider obtaining a sleep apnea study?
Refer patients for a sleep study when snoring, snorting, gasping, or pauses in breathing occur during sleep, or in the case of daytime sleepiness, fatigue, or unrefreshing sleep that cannot be explained by another medical or psychiatric illness.2 A sleep specialist can determine the most appropriate intervention for sleep-disordered breathing.
An apneic event is characterized by complete cessation of airflow; hypopnea is a partially compromised airway. In either event, at least a 3% decrease in oxygen saturation occurs for at least 10 seconds.3 A diagnosis of obstructive sleep apnea or hypopnea is required when polysomnography reveals either of:
• ≥5 episodes of apnea or hypopnea, or both, per hour of sleep, with symptoms of a rhythmic breathing disturbance or daytime sleepiness or fatigue
• ≥15 episodes of apnea or hypopnea, or both, per hour of sleep, regardless of accompanying symptoms.2
What are the treatment options?
• Continuous positive airway pressure (CPAP) machines.
• Surgical procedures include adeno-tonsillectomy in children and surgical maxilla-mandibular advancement or palatal implants for adults.
• A novel implantable electrical stimulation device stimulates the hypoglossal nerve, which activates the genioglossus muscle, thus moving the tongue forward to open the airway.
• An anterior mandibular positioning (AMP) device increases the diameter of the retroglossal space by preventing posterior movement of the mandible and tongue, thereby limiting encroachment on the airway diameter and reducing the potential for collapse.1-4
When should you recommend an AMP device?
Consider recommending an AMP device to treat sleep-disordered breathing when (1) lifestyle changes, such as sleep hygiene, weight loss, and stopping sedatives, do not work and (2) a CPAP machine or a surgical procedure is contraindicated or has been ineffective.1 An AMP device can minimize snoring and relieve airway obstruction, especially in patients with supine position-related apnea.4 To keep the airway open in non-supine position-related cases, an AMP device might be indicated in addition to CPAP delivered nasally.1
This plastic oral appliance is either a 1- or 2-piece design, and looks and is sized similarly to an athletic mouth-protection guard or an oral anti-bruxism tooth-protection appliance. It is affixed to the mandible and maxillary arches by clasps (Figure).
An AMP device often is most beneficial for supine-dependent sleep apnea patients and those with loud snoring, without sleep apnea.4 Response is best in young adults and in patients who have a low body mass index, are free of sedatives, and have appropriate cephalometrics of the oral, dental, or pharyngeal anatomy. Improved sleep architecture, continuous sleep with less snoring, and increased daytime alertness are observed in patients who respond to an AMP device.
An AMP device is contraindicated when the device cannot be affixed to the dental arches and in some patients with an anatomical or pain-related temporomandibular joint disorder.5 The device is easy to use, noninvasive, readily accessible, and less expensive than alternatives.3
How can you help maintain treatment adherence?
AMP devices can induce adverse effects, including dental pain or discomfort through orthodontic alterations; patient reports and follow-up can yield detection and device adjustments can alleviate such problems. Adherence generally is good, with complaints usually limited to minor tooth discomfort, occlusive changes, and increased or decreased salivation.5 In our clinical experience, many patients find these devices comfortable and easy to use, but might complain of feeling awkward when wearing them.
Changes in occlusion can occur during long-term treatment with an AMP device. Proper fitting is essential to facilitate a more open airway and the ability to speak and drink fluids, and to maintain safety, even if vomiting occurs while the device is in place.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Epstein LJ, Kristo D, Strollo PJ, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009;5(3):263-276.
2. Diagnostic and statistical manual of mental disorders, 5th ed. Washington, DC: American Psychiatric Association; 2013.
3. de Britto Teixeira AO, Abi-Ramia LB, de Oliveira Almeida MA. Treatment of obstructive sleep apnea with oral appliances. Prog Orthod. 2013;14:10.
4. Marklund M, Stenlund H, Franklin K. Mandibular advancement devices in 630 men and women with obstructive sleep apnea and snoring: tolerability and predictors of treatment success. Chest. 2004;125(4):1270-1278.
5. Ferguson KA, Cartwright R, Rogers R, et al. Oral appliances for snoring and obstructive sleep apnea: a review. Sleep. 2006;29(2):244-262.
Snoring, snorting, gasping, and obstructive sleep apnea are caused by collapse of the pharyngeal airway during sleep.1 Pathophysiology includes a combination of anatomical and physiological variables.1 Common anatomical predisposing conditions include abnormalities of pharyngeal, lingual, and dental arches; physiological concerns are advancing age, male sex, obesity, use of sedatives, body positioning, and reduced muscle tone during rapid eye movement sleep. Coexistence of anatomic and physiological elements can produce significant narrowing of the upper airway.
Comorbidities include vascular, metabolic, and psychiatric conditions. As many as one-third of people with symptoms of sleep apnea report depressed mood; approximately 10% of these patients meet criteria for moderate or severe depression.2
In short, sleep-disordered breathing has a globally negative effect on mental health.
When should you consider obtaining a sleep apnea study?
Refer patients for a sleep study when snoring, snorting, gasping, or pauses in breathing occur during sleep, or in the case of daytime sleepiness, fatigue, or unrefreshing sleep that cannot be explained by another medical or psychiatric illness.2 A sleep specialist can determine the most appropriate intervention for sleep-disordered breathing.
An apneic event is characterized by complete cessation of airflow; hypopnea is a partially compromised airway. In either event, at least a 3% decrease in oxygen saturation occurs for at least 10 seconds.3 A diagnosis of obstructive sleep apnea or hypopnea is required when polysomnography reveals either of:
• ≥5 episodes of apnea or hypopnea, or both, per hour of sleep, with symptoms of a rhythmic breathing disturbance or daytime sleepiness or fatigue
• ≥15 episodes of apnea or hypopnea, or both, per hour of sleep, regardless of accompanying symptoms.2
What are the treatment options?
• Continuous positive airway pressure (CPAP) machines.
• Surgical procedures include adeno-tonsillectomy in children and surgical maxilla-mandibular advancement or palatal implants for adults.
• A novel implantable electrical stimulation device stimulates the hypoglossal nerve, which activates the genioglossus muscle, thus moving the tongue forward to open the airway.
• An anterior mandibular positioning (AMP) device increases the diameter of the retroglossal space by preventing posterior movement of the mandible and tongue, thereby limiting encroachment on the airway diameter and reducing the potential for collapse.1-4
When should you recommend an AMP device?
Consider recommending an AMP device to treat sleep-disordered breathing when (1) lifestyle changes, such as sleep hygiene, weight loss, and stopping sedatives, do not work and (2) a CPAP machine or a surgical procedure is contraindicated or has been ineffective.1 An AMP device can minimize snoring and relieve airway obstruction, especially in patients with supine position-related apnea.4 To keep the airway open in non-supine position-related cases, an AMP device might be indicated in addition to CPAP delivered nasally.1
This plastic oral appliance is either a 1- or 2-piece design, and looks and is sized similarly to an athletic mouth-protection guard or an oral anti-bruxism tooth-protection appliance. It is affixed to the mandible and maxillary arches by clasps (Figure).
An AMP device often is most beneficial for supine-dependent sleep apnea patients and those with loud snoring, without sleep apnea.4 Response is best in young adults and in patients who have a low body mass index, are free of sedatives, and have appropriate cephalometrics of the oral, dental, or pharyngeal anatomy. Improved sleep architecture, continuous sleep with less snoring, and increased daytime alertness are observed in patients who respond to an AMP device.
An AMP device is contraindicated when the device cannot be affixed to the dental arches and in some patients with an anatomical or pain-related temporomandibular joint disorder.5 The device is easy to use, noninvasive, readily accessible, and less expensive than alternatives.3
How can you help maintain treatment adherence?
AMP devices can induce adverse effects, including dental pain or discomfort through orthodontic alterations; patient reports and follow-up can yield detection and device adjustments can alleviate such problems. Adherence generally is good, with complaints usually limited to minor tooth discomfort, occlusive changes, and increased or decreased salivation.5 In our clinical experience, many patients find these devices comfortable and easy to use, but might complain of feeling awkward when wearing them.
Changes in occlusion can occur during long-term treatment with an AMP device. Proper fitting is essential to facilitate a more open airway and the ability to speak and drink fluids, and to maintain safety, even if vomiting occurs while the device is in place.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
Snoring, snorting, gasping, and obstructive sleep apnea are caused by collapse of the pharyngeal airway during sleep.1 Pathophysiology includes a combination of anatomical and physiological variables.1 Common anatomical predisposing conditions include abnormalities of pharyngeal, lingual, and dental arches; physiological concerns are advancing age, male sex, obesity, use of sedatives, body positioning, and reduced muscle tone during rapid eye movement sleep. Coexistence of anatomic and physiological elements can produce significant narrowing of the upper airway.
Comorbidities include vascular, metabolic, and psychiatric conditions. As many as one-third of people with symptoms of sleep apnea report depressed mood; approximately 10% of these patients meet criteria for moderate or severe depression.2
In short, sleep-disordered breathing has a globally negative effect on mental health.
When should you consider obtaining a sleep apnea study?
Refer patients for a sleep study when snoring, snorting, gasping, or pauses in breathing occur during sleep, or in the case of daytime sleepiness, fatigue, or unrefreshing sleep that cannot be explained by another medical or psychiatric illness.2 A sleep specialist can determine the most appropriate intervention for sleep-disordered breathing.
An apneic event is characterized by complete cessation of airflow; hypopnea is a partially compromised airway. In either event, at least a 3% decrease in oxygen saturation occurs for at least 10 seconds.3 A diagnosis of obstructive sleep apnea or hypopnea is required when polysomnography reveals either of:
• ≥5 episodes of apnea or hypopnea, or both, per hour of sleep, with symptoms of a rhythmic breathing disturbance or daytime sleepiness or fatigue
• ≥15 episodes of apnea or hypopnea, or both, per hour of sleep, regardless of accompanying symptoms.2
What are the treatment options?
• Continuous positive airway pressure (CPAP) machines.
• Surgical procedures include adeno-tonsillectomy in children and surgical maxilla-mandibular advancement or palatal implants for adults.
• A novel implantable electrical stimulation device stimulates the hypoglossal nerve, which activates the genioglossus muscle, thus moving the tongue forward to open the airway.
• An anterior mandibular positioning (AMP) device increases the diameter of the retroglossal space by preventing posterior movement of the mandible and tongue, thereby limiting encroachment on the airway diameter and reducing the potential for collapse.1-4
When should you recommend an AMP device?
Consider recommending an AMP device to treat sleep-disordered breathing when (1) lifestyle changes, such as sleep hygiene, weight loss, and stopping sedatives, do not work and (2) a CPAP machine or a surgical procedure is contraindicated or has been ineffective.1 An AMP device can minimize snoring and relieve airway obstruction, especially in patients with supine position-related apnea.4 To keep the airway open in non-supine position-related cases, an AMP device might be indicated in addition to CPAP delivered nasally.1
This plastic oral appliance is either a 1- or 2-piece design, and looks and is sized similarly to an athletic mouth-protection guard or an oral anti-bruxism tooth-protection appliance. It is affixed to the mandible and maxillary arches by clasps (Figure).
An AMP device often is most beneficial for supine-dependent sleep apnea patients and those with loud snoring, without sleep apnea.4 Response is best in young adults and in patients who have a low body mass index, are free of sedatives, and have appropriate cephalometrics of the oral, dental, or pharyngeal anatomy. Improved sleep architecture, continuous sleep with less snoring, and increased daytime alertness are observed in patients who respond to an AMP device.
An AMP device is contraindicated when the device cannot be affixed to the dental arches and in some patients with an anatomical or pain-related temporomandibular joint disorder.5 The device is easy to use, noninvasive, readily accessible, and less expensive than alternatives.3
How can you help maintain treatment adherence?
AMP devices can induce adverse effects, including dental pain or discomfort through orthodontic alterations; patient reports and follow-up can yield detection and device adjustments can alleviate such problems. Adherence generally is good, with complaints usually limited to minor tooth discomfort, occlusive changes, and increased or decreased salivation.5 In our clinical experience, many patients find these devices comfortable and easy to use, but might complain of feeling awkward when wearing them.
Changes in occlusion can occur during long-term treatment with an AMP device. Proper fitting is essential to facilitate a more open airway and the ability to speak and drink fluids, and to maintain safety, even if vomiting occurs while the device is in place.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Epstein LJ, Kristo D, Strollo PJ, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009;5(3):263-276.
2. Diagnostic and statistical manual of mental disorders, 5th ed. Washington, DC: American Psychiatric Association; 2013.
3. de Britto Teixeira AO, Abi-Ramia LB, de Oliveira Almeida MA. Treatment of obstructive sleep apnea with oral appliances. Prog Orthod. 2013;14:10.
4. Marklund M, Stenlund H, Franklin K. Mandibular advancement devices in 630 men and women with obstructive sleep apnea and snoring: tolerability and predictors of treatment success. Chest. 2004;125(4):1270-1278.
5. Ferguson KA, Cartwright R, Rogers R, et al. Oral appliances for snoring and obstructive sleep apnea: a review. Sleep. 2006;29(2):244-262.
1. Epstein LJ, Kristo D, Strollo PJ, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009;5(3):263-276.
2. Diagnostic and statistical manual of mental disorders, 5th ed. Washington, DC: American Psychiatric Association; 2013.
3. de Britto Teixeira AO, Abi-Ramia LB, de Oliveira Almeida MA. Treatment of obstructive sleep apnea with oral appliances. Prog Orthod. 2013;14:10.
4. Marklund M, Stenlund H, Franklin K. Mandibular advancement devices in 630 men and women with obstructive sleep apnea and snoring: tolerability and predictors of treatment success. Chest. 2004;125(4):1270-1278.
5. Ferguson KA, Cartwright R, Rogers R, et al. Oral appliances for snoring and obstructive sleep apnea: a review. Sleep. 2006;29(2):244-262.
Have you RULED O2uT medical illness in the presumptive psychiatric patient?
What a practitioner might identify and report as “psychiatric” symptoms or signs cannot always be explained in terms of psychological stress or a psychiatric disorder. In fact, a range of medical1 and neurologic2 illnesses can manifest in ways that appear psychiatric in nature. Common examples are sleep and thyroid disorders; deficiencies of vitamin D, folate, and B12; Parkinson’s disease; and anti-N-methyl-d-aspartate receptor autoimmune encephalitis.
People who have a medical illness with what appear to be psychiatric manifestations often elude identification and diagnosis because they do not visit a health care provider for any of several reasons, including difficulty obtaining health insurance. Instead, they might seek care in an emergency room (ER).
When such patients present for evaluation, it is easy—especially in a fast-paced ER—to miss the underlying cause of their illness. Some are then treated on the assumption that their diagnosis is psychiatric, while their medical illness goes unidentified.3
We propose a mnemonic, RULED O2uT, as a reminder in the ER (and any other setting) of the need to rule out physical illness before treating a patient for a psychiatric disorder. To demonstrate how the work-up of a patient whose medical illness was obscured by psychiatric signs and symptoms could benefit from applying RULED O2uT, we also present a case.
CASE REPORT
A man with a medical illness who presented with psychiatric symptoms
Mr. Z, in his late 40s, is brought to the ER by his sister for evaluation of depressed mood of 6 to 8 months’ duration. He has no psychiatric history.
On evaluation, Mr. Z does not remember an event or stressors that could have triggered depression. He describes complete loss of motivation for activities of daily living, such as personal grooming. He has stopped leaving the house and meeting friends and family members.
Mr. Z’s sister is concerned for his well-being because he has been living without heat and electricity, which were disconnected for nonpayment. Mr. Z reveals that he has not seen his primary care physician “for 20 or 25 years,” although he recently sought care in the ER of another hospital because of mild gait instability for several months.
Mr. Z has a blunted affect, with linear and goal-directed thought processes. He denies suicidal ideation. Laboratory testing, including a comprehensive metabolic panel, complete blood count, and urine toxicology and urinalysis, are negative.
A non-contrast CT scan of the head reveals foci of low attenuation in the left frontal corona radiata. Follow-up MRI of the brain, with and without contrast, shows extensive supratentorial and infratentorial demyelinating lesions consistent with multiple sclerosis (MS). Several cerebral lesions in the white matter are consistent with active demyelination.
Mr. Z is admitted to the neurology service and started on methylprednisolone for MS. The psychiatry consultation-liaison team prescribes sertraline, 50 mg titrated to 100 mg, for depression.
Detailed history means better overall evaluation
Mr. Z presented to the busy ER with psychiatric symptoms. It was easy to make a diagnosis of depression and refer him to the outpatient psychiatrist. However, a detailed history provided pertinent information about Mr. Z such as no regular medical check-ups, no family history of mental illness, and gait disturbance in absence of physical injury. This enabled the physicians to conduct a thorough evaluation including a neurologic examination, laboratory tests, and imaging of the brain.
The 8 components of RULED O2uT
Rx interactions. Review medications that the patient is taking or recently stopped taking, to rule out drug−drug interactions and adverse effects.
Unusual presentation. Be mindful of any unusual presentation. For example, sudden onset of psychiatric symptoms with seizures or hypersensitivity to the sun with depression or psychosis.
Labs. Obtain appropriate blood work, including:
• comprehensive metabolic panel
• complete blood count
• thyroid-stimulating hormone (myxedema, thyrotoxicosis)
• delta-aminolevulinic acid and porphobilinogen (acute intermittent porphyria)
• antinuclear antibody (systemic lupus erythematosus)
• B12 level
• fluorescent treponemal antibody absorption test (neurosyphilis)
• serum ceruloplasmin and copper (Wilson’s disease).
Examination. Perform a thorough examination, including a proper neurological exam. This is especially important when you see signs, or the patient reports symptoms, that cannot be explained by depression alone. An abnormality or change in gait, for example, might be a consequence of injury or a manifestation of MS, stroke, or Parkinson’s disease. Additional testing, such as CT of the head or lumbar puncture, might be appropriate to supplement or clarify findings of the exam. Mr. Z’s neurologic exam revealed weakness in his left leg with variability in reflexes.
Drugs. Ensure that a patient presenting with new-onset psychosis is not taking dopaminergic medications or steroids and, based on results of a toxicology screen, is not under the influence of stimulants or hallucinogens.
Onset and Office. Determine:
• the time since onset of symptoms; this is crucial to differentiate psychiatric disorders and ruling out a nonpsychiatric cause of the patient’s presentation
• if the patient gets a regular medical check-up with her (his) primary care physician.
Thorough history. Obtain a thorough history so that you have a clear picture of the patient’s current situation; this includes medical history and family history of neurologic and psychiatric disorders and substance abuse.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Rahul R, Pieters T. An unusual psychiatric presentation of polycythaemia ‘Difficulties lie in our habits of thought rather than in the nature of things’ Andre Tardieu. BMJ Case Rep. 2013. pii: bcr2012008215. doi: 10.1136/bcr-2012-008215.
2. Butler C, Zeman AZ. Neurological syndromes which can be mistaken for psychiatric conditions. J Neurol Neurosurg Psychiatry. 2005;76(suppl 1):i31-i38.
3. Roie EV, Labarque V, Renard M, et al. Obsessive-compulsive behavior as presenting symptom of primary antiphospholipid syndrome. Psychosom Med. 2013;75(3):326-330.
What a practitioner might identify and report as “psychiatric” symptoms or signs cannot always be explained in terms of psychological stress or a psychiatric disorder. In fact, a range of medical1 and neurologic2 illnesses can manifest in ways that appear psychiatric in nature. Common examples are sleep and thyroid disorders; deficiencies of vitamin D, folate, and B12; Parkinson’s disease; and anti-N-methyl-d-aspartate receptor autoimmune encephalitis.
People who have a medical illness with what appear to be psychiatric manifestations often elude identification and diagnosis because they do not visit a health care provider for any of several reasons, including difficulty obtaining health insurance. Instead, they might seek care in an emergency room (ER).
When such patients present for evaluation, it is easy—especially in a fast-paced ER—to miss the underlying cause of their illness. Some are then treated on the assumption that their diagnosis is psychiatric, while their medical illness goes unidentified.3
We propose a mnemonic, RULED O2uT, as a reminder in the ER (and any other setting) of the need to rule out physical illness before treating a patient for a psychiatric disorder. To demonstrate how the work-up of a patient whose medical illness was obscured by psychiatric signs and symptoms could benefit from applying RULED O2uT, we also present a case.
CASE REPORT
A man with a medical illness who presented with psychiatric symptoms
Mr. Z, in his late 40s, is brought to the ER by his sister for evaluation of depressed mood of 6 to 8 months’ duration. He has no psychiatric history.
On evaluation, Mr. Z does not remember an event or stressors that could have triggered depression. He describes complete loss of motivation for activities of daily living, such as personal grooming. He has stopped leaving the house and meeting friends and family members.
Mr. Z’s sister is concerned for his well-being because he has been living without heat and electricity, which were disconnected for nonpayment. Mr. Z reveals that he has not seen his primary care physician “for 20 or 25 years,” although he recently sought care in the ER of another hospital because of mild gait instability for several months.
Mr. Z has a blunted affect, with linear and goal-directed thought processes. He denies suicidal ideation. Laboratory testing, including a comprehensive metabolic panel, complete blood count, and urine toxicology and urinalysis, are negative.
A non-contrast CT scan of the head reveals foci of low attenuation in the left frontal corona radiata. Follow-up MRI of the brain, with and without contrast, shows extensive supratentorial and infratentorial demyelinating lesions consistent with multiple sclerosis (MS). Several cerebral lesions in the white matter are consistent with active demyelination.
Mr. Z is admitted to the neurology service and started on methylprednisolone for MS. The psychiatry consultation-liaison team prescribes sertraline, 50 mg titrated to 100 mg, for depression.
Detailed history means better overall evaluation
Mr. Z presented to the busy ER with psychiatric symptoms. It was easy to make a diagnosis of depression and refer him to the outpatient psychiatrist. However, a detailed history provided pertinent information about Mr. Z such as no regular medical check-ups, no family history of mental illness, and gait disturbance in absence of physical injury. This enabled the physicians to conduct a thorough evaluation including a neurologic examination, laboratory tests, and imaging of the brain.
The 8 components of RULED O2uT
Rx interactions. Review medications that the patient is taking or recently stopped taking, to rule out drug−drug interactions and adverse effects.
Unusual presentation. Be mindful of any unusual presentation. For example, sudden onset of psychiatric symptoms with seizures or hypersensitivity to the sun with depression or psychosis.
Labs. Obtain appropriate blood work, including:
• comprehensive metabolic panel
• complete blood count
• thyroid-stimulating hormone (myxedema, thyrotoxicosis)
• delta-aminolevulinic acid and porphobilinogen (acute intermittent porphyria)
• antinuclear antibody (systemic lupus erythematosus)
• B12 level
• fluorescent treponemal antibody absorption test (neurosyphilis)
• serum ceruloplasmin and copper (Wilson’s disease).
Examination. Perform a thorough examination, including a proper neurological exam. This is especially important when you see signs, or the patient reports symptoms, that cannot be explained by depression alone. An abnormality or change in gait, for example, might be a consequence of injury or a manifestation of MS, stroke, or Parkinson’s disease. Additional testing, such as CT of the head or lumbar puncture, might be appropriate to supplement or clarify findings of the exam. Mr. Z’s neurologic exam revealed weakness in his left leg with variability in reflexes.
Drugs. Ensure that a patient presenting with new-onset psychosis is not taking dopaminergic medications or steroids and, based on results of a toxicology screen, is not under the influence of stimulants or hallucinogens.
Onset and Office. Determine:
• the time since onset of symptoms; this is crucial to differentiate psychiatric disorders and ruling out a nonpsychiatric cause of the patient’s presentation
• if the patient gets a regular medical check-up with her (his) primary care physician.
Thorough history. Obtain a thorough history so that you have a clear picture of the patient’s current situation; this includes medical history and family history of neurologic and psychiatric disorders and substance abuse.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
What a practitioner might identify and report as “psychiatric” symptoms or signs cannot always be explained in terms of psychological stress or a psychiatric disorder. In fact, a range of medical1 and neurologic2 illnesses can manifest in ways that appear psychiatric in nature. Common examples are sleep and thyroid disorders; deficiencies of vitamin D, folate, and B12; Parkinson’s disease; and anti-N-methyl-d-aspartate receptor autoimmune encephalitis.
People who have a medical illness with what appear to be psychiatric manifestations often elude identification and diagnosis because they do not visit a health care provider for any of several reasons, including difficulty obtaining health insurance. Instead, they might seek care in an emergency room (ER).
When such patients present for evaluation, it is easy—especially in a fast-paced ER—to miss the underlying cause of their illness. Some are then treated on the assumption that their diagnosis is psychiatric, while their medical illness goes unidentified.3
We propose a mnemonic, RULED O2uT, as a reminder in the ER (and any other setting) of the need to rule out physical illness before treating a patient for a psychiatric disorder. To demonstrate how the work-up of a patient whose medical illness was obscured by psychiatric signs and symptoms could benefit from applying RULED O2uT, we also present a case.
CASE REPORT
A man with a medical illness who presented with psychiatric symptoms
Mr. Z, in his late 40s, is brought to the ER by his sister for evaluation of depressed mood of 6 to 8 months’ duration. He has no psychiatric history.
On evaluation, Mr. Z does not remember an event or stressors that could have triggered depression. He describes complete loss of motivation for activities of daily living, such as personal grooming. He has stopped leaving the house and meeting friends and family members.
Mr. Z’s sister is concerned for his well-being because he has been living without heat and electricity, which were disconnected for nonpayment. Mr. Z reveals that he has not seen his primary care physician “for 20 or 25 years,” although he recently sought care in the ER of another hospital because of mild gait instability for several months.
Mr. Z has a blunted affect, with linear and goal-directed thought processes. He denies suicidal ideation. Laboratory testing, including a comprehensive metabolic panel, complete blood count, and urine toxicology and urinalysis, are negative.
A non-contrast CT scan of the head reveals foci of low attenuation in the left frontal corona radiata. Follow-up MRI of the brain, with and without contrast, shows extensive supratentorial and infratentorial demyelinating lesions consistent with multiple sclerosis (MS). Several cerebral lesions in the white matter are consistent with active demyelination.
Mr. Z is admitted to the neurology service and started on methylprednisolone for MS. The psychiatry consultation-liaison team prescribes sertraline, 50 mg titrated to 100 mg, for depression.
Detailed history means better overall evaluation
Mr. Z presented to the busy ER with psychiatric symptoms. It was easy to make a diagnosis of depression and refer him to the outpatient psychiatrist. However, a detailed history provided pertinent information about Mr. Z such as no regular medical check-ups, no family history of mental illness, and gait disturbance in absence of physical injury. This enabled the physicians to conduct a thorough evaluation including a neurologic examination, laboratory tests, and imaging of the brain.
The 8 components of RULED O2uT
Rx interactions. Review medications that the patient is taking or recently stopped taking, to rule out drug−drug interactions and adverse effects.
Unusual presentation. Be mindful of any unusual presentation. For example, sudden onset of psychiatric symptoms with seizures or hypersensitivity to the sun with depression or psychosis.
Labs. Obtain appropriate blood work, including:
• comprehensive metabolic panel
• complete blood count
• thyroid-stimulating hormone (myxedema, thyrotoxicosis)
• delta-aminolevulinic acid and porphobilinogen (acute intermittent porphyria)
• antinuclear antibody (systemic lupus erythematosus)
• B12 level
• fluorescent treponemal antibody absorption test (neurosyphilis)
• serum ceruloplasmin and copper (Wilson’s disease).
Examination. Perform a thorough examination, including a proper neurological exam. This is especially important when you see signs, or the patient reports symptoms, that cannot be explained by depression alone. An abnormality or change in gait, for example, might be a consequence of injury or a manifestation of MS, stroke, or Parkinson’s disease. Additional testing, such as CT of the head or lumbar puncture, might be appropriate to supplement or clarify findings of the exam. Mr. Z’s neurologic exam revealed weakness in his left leg with variability in reflexes.
Drugs. Ensure that a patient presenting with new-onset psychosis is not taking dopaminergic medications or steroids and, based on results of a toxicology screen, is not under the influence of stimulants or hallucinogens.
Onset and Office. Determine:
• the time since onset of symptoms; this is crucial to differentiate psychiatric disorders and ruling out a nonpsychiatric cause of the patient’s presentation
• if the patient gets a regular medical check-up with her (his) primary care physician.
Thorough history. Obtain a thorough history so that you have a clear picture of the patient’s current situation; this includes medical history and family history of neurologic and psychiatric disorders and substance abuse.
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Rahul R, Pieters T. An unusual psychiatric presentation of polycythaemia ‘Difficulties lie in our habits of thought rather than in the nature of things’ Andre Tardieu. BMJ Case Rep. 2013. pii: bcr2012008215. doi: 10.1136/bcr-2012-008215.
2. Butler C, Zeman AZ. Neurological syndromes which can be mistaken for psychiatric conditions. J Neurol Neurosurg Psychiatry. 2005;76(suppl 1):i31-i38.
3. Roie EV, Labarque V, Renard M, et al. Obsessive-compulsive behavior as presenting symptom of primary antiphospholipid syndrome. Psychosom Med. 2013;75(3):326-330.
1. Rahul R, Pieters T. An unusual psychiatric presentation of polycythaemia ‘Difficulties lie in our habits of thought rather than in the nature of things’ Andre Tardieu. BMJ Case Rep. 2013. pii: bcr2012008215. doi: 10.1136/bcr-2012-008215.
2. Butler C, Zeman AZ. Neurological syndromes which can be mistaken for psychiatric conditions. J Neurol Neurosurg Psychiatry. 2005;76(suppl 1):i31-i38.
3. Roie EV, Labarque V, Renard M, et al. Obsessive-compulsive behavior as presenting symptom of primary antiphospholipid syndrome. Psychosom Med. 2013;75(3):326-330.
Assessing tremor to rule out psychogenic origin: It’s tricky
Tremors are a rhythmic and oscillatory movement of a body part with a relatively constant frequency.1 Several subtypes of tremors are classified on the basis of whether they occur during static or kinetic body positioning. Assessing tremors to rule out psychogenic origin is one of the trickiest tasks for a psychiatrist (Table 12). Non-organic movement disorders are not rare, and all common organic movement disorders can be mimicked by non-organic presentations.
Diagnostic approach
Start by categorizing the tremor based on its activation condition (at rest, kinetic or intentional, postural or isometric), topographic distribution, and frequency. Observe the patient sitting in a chair with his hands on his lap for resting tremor. Postural or kinetic tremors can be assessed by stretching the arms and performing a finger-to-nose test. A resting tremor can indicate parkinsonism; intention tremor may indicate a cerebellar lesion. A psychogenic tremor can occur at rest or during postural or active movement, and often will occur in all 3 situations (Table 2).1-3
Some of the maneuvers listed in Table 3 are helpful to distinguish a psychogenic from an organic cause. The key is to look for variability in direction, amplitude, and frequency. Psychogenic tremor often increases when the limb is examined and reduces upon distraction, and also might be exacerbated with movement of other limbs. Patients with psychogenic tremor often have other “non-organic” neurologic signs, such as give-way weakness, deliberate slowness carrying out requested voluntary movement, and sensory signs that contradict neuroanatomical principles.
Investigation
Proceed as follows:
1. Perform laboratory testing: thyroid function panel and serum copper and ceruloplasmin levels.2
2. Perform surface electromyography to differentiate Parkinson’s disease and benign tremor disorders.2
3. Obtain a MRI to assess atypical tremor; findings might reveal Wilson’s disease (basal ganglia and brainstem involvement) or fragile X-associated tremor/ataxia syndrome (pontocerebellar hypoplasia or cerebral white matter involvement).3
4. Consider dopaminergic functional imaging scanning. When positive, the scan can reveal symptoms of parkinsonism; negative findings can help consolidate a diagnosis of psychogenic tremor.3
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Bain P, Brin M, Deuschl G, et al. Criteria for the diagnosis of essential tremor. Neurology. 2000;54(11 suppl 4):S7.
2. Alty JE, Kempster PA. A practical guide to the differential diagnosis of tremor. Postgrad Med J. 2011;87(1031):623-629.
3. Crawford P, Zimmerman EE. Differentiation and diagnosis of tremor. Am Fam Physician. 2011;83(6):697-702.
Tremors are a rhythmic and oscillatory movement of a body part with a relatively constant frequency.1 Several subtypes of tremors are classified on the basis of whether they occur during static or kinetic body positioning. Assessing tremors to rule out psychogenic origin is one of the trickiest tasks for a psychiatrist (Table 12). Non-organic movement disorders are not rare, and all common organic movement disorders can be mimicked by non-organic presentations.
Diagnostic approach
Start by categorizing the tremor based on its activation condition (at rest, kinetic or intentional, postural or isometric), topographic distribution, and frequency. Observe the patient sitting in a chair with his hands on his lap for resting tremor. Postural or kinetic tremors can be assessed by stretching the arms and performing a finger-to-nose test. A resting tremor can indicate parkinsonism; intention tremor may indicate a cerebellar lesion. A psychogenic tremor can occur at rest or during postural or active movement, and often will occur in all 3 situations (Table 2).1-3
Some of the maneuvers listed in Table 3 are helpful to distinguish a psychogenic from an organic cause. The key is to look for variability in direction, amplitude, and frequency. Psychogenic tremor often increases when the limb is examined and reduces upon distraction, and also might be exacerbated with movement of other limbs. Patients with psychogenic tremor often have other “non-organic” neurologic signs, such as give-way weakness, deliberate slowness carrying out requested voluntary movement, and sensory signs that contradict neuroanatomical principles.
Investigation
Proceed as follows:
1. Perform laboratory testing: thyroid function panel and serum copper and ceruloplasmin levels.2
2. Perform surface electromyography to differentiate Parkinson’s disease and benign tremor disorders.2
3. Obtain a MRI to assess atypical tremor; findings might reveal Wilson’s disease (basal ganglia and brainstem involvement) or fragile X-associated tremor/ataxia syndrome (pontocerebellar hypoplasia or cerebral white matter involvement).3
4. Consider dopaminergic functional imaging scanning. When positive, the scan can reveal symptoms of parkinsonism; negative findings can help consolidate a diagnosis of psychogenic tremor.3
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
Tremors are a rhythmic and oscillatory movement of a body part with a relatively constant frequency.1 Several subtypes of tremors are classified on the basis of whether they occur during static or kinetic body positioning. Assessing tremors to rule out psychogenic origin is one of the trickiest tasks for a psychiatrist (Table 12). Non-organic movement disorders are not rare, and all common organic movement disorders can be mimicked by non-organic presentations.
Diagnostic approach
Start by categorizing the tremor based on its activation condition (at rest, kinetic or intentional, postural or isometric), topographic distribution, and frequency. Observe the patient sitting in a chair with his hands on his lap for resting tremor. Postural or kinetic tremors can be assessed by stretching the arms and performing a finger-to-nose test. A resting tremor can indicate parkinsonism; intention tremor may indicate a cerebellar lesion. A psychogenic tremor can occur at rest or during postural or active movement, and often will occur in all 3 situations (Table 2).1-3
Some of the maneuvers listed in Table 3 are helpful to distinguish a psychogenic from an organic cause. The key is to look for variability in direction, amplitude, and frequency. Psychogenic tremor often increases when the limb is examined and reduces upon distraction, and also might be exacerbated with movement of other limbs. Patients with psychogenic tremor often have other “non-organic” neurologic signs, such as give-way weakness, deliberate slowness carrying out requested voluntary movement, and sensory signs that contradict neuroanatomical principles.
Investigation
Proceed as follows:
1. Perform laboratory testing: thyroid function panel and serum copper and ceruloplasmin levels.2
2. Perform surface electromyography to differentiate Parkinson’s disease and benign tremor disorders.2
3. Obtain a MRI to assess atypical tremor; findings might reveal Wilson’s disease (basal ganglia and brainstem involvement) or fragile X-associated tremor/ataxia syndrome (pontocerebellar hypoplasia or cerebral white matter involvement).3
4. Consider dopaminergic functional imaging scanning. When positive, the scan can reveal symptoms of parkinsonism; negative findings can help consolidate a diagnosis of psychogenic tremor.3
Disclosures
The authors report no financial relationships with any company whose products are mentioned in this article or with manufacturers of competing products.
1. Bain P, Brin M, Deuschl G, et al. Criteria for the diagnosis of essential tremor. Neurology. 2000;54(11 suppl 4):S7.
2. Alty JE, Kempster PA. A practical guide to the differential diagnosis of tremor. Postgrad Med J. 2011;87(1031):623-629.
3. Crawford P, Zimmerman EE. Differentiation and diagnosis of tremor. Am Fam Physician. 2011;83(6):697-702.
1. Bain P, Brin M, Deuschl G, et al. Criteria for the diagnosis of essential tremor. Neurology. 2000;54(11 suppl 4):S7.
2. Alty JE, Kempster PA. A practical guide to the differential diagnosis of tremor. Postgrad Med J. 2011;87(1031):623-629.
3. Crawford P, Zimmerman EE. Differentiation and diagnosis of tremor. Am Fam Physician. 2011;83(6):697-702.