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Finding balance: Optimizing medication prescribing in older patients
More than one-third of older adults in the United States take 5 or more medications. Consider deprescribing.
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New Oral Anticoagulants Safe and Effective for Atrial Fibrillation Treatment
Clinical question: Is there a difference in efficacy and safety among new oral anticoagulants compared to warfarin in subgroups of patients with...
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Sepsis Diagnoses Are Common in ED, but Many Septic Patients in the ED Do Not Receive Antibiotics
Clinical question: Has the frequency of sepsis rates, along with administration of antibiotics in U.S.
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Multifaceted Discharge Interventions Reduce Rates of Pediatric Readmission and Post-Hospital ED Utilization
Clinical question: Do interventions at discharge reduce the rate of readmissions and post-hospitalization ED visits among pediatric patients?...
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Warfarin Initiation in Atrial Fibrillation Associated with Increased Short-Term Risk of Stroke
Clinical question: Is the initiation of warfarin associated with an increased risk of ischemic stroke in patients with atrial fibrillation (Afib...
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Comorbidities Contribute to Potentially Avoidable Hospital Readmissions
Clinical question: What is the role of comorbidities in 30-day potentially avoidable readmissions? Background: Higher comorbidity burden has been...
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Uncomplicated Skin Infections in Ambulatory Setting Commonly Involve Avoidable Antibiotic Exposure
Clinical question: What are the current prescribing practices for antibiotics used to treat skin and soft tissue infections in the outpatient...
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Resident Handoff Bundle Reduces Medical Errors and Adverse Events, Improves Handoff Quality
Clinical question: In a pediatric inpatient setting, is the use of a handoff program associated with improved patient safety measures and handoff...
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Modified IV Acetylcysteine Infusion Reduces Adverse Effects
Clinical question: Does a shorter regimen of IV acetylcysteine reduce adverse effects compared to the standard regimen? Background: Acetaminophen...
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No Mortality Benefit with Treatment of Single Peripheral Pulmonary Emboli
Clinical question: Does treatment of single peripheral pulmonary emboli impact mortality and rates of post-discharge venous thromboembolism (VTE...
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Healthcare-Associated Infections Continue to Impact the U.S. Healthcare System Financially
Clinical question: What is the estimated cost of healthcare-associated infections (HAI) to the U.S. healthcare system? Background: In spite of...
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Hospitalist Reviews on Healthcare-associated Infections, Mortality Benefit with Single Peripheral Pulmonary Emboli, Oral Anticoagulants to Treat Atrial Fibrillation
Also reviewed this month: comorbidities and avoidable hospital readmissions, effect of resident handoff bundles on medical errors, pediatric...
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Surgical-Site-Infection Risk Not Associated with Prophylactic Antibiotic Timing
Administering antibiotics 60 minutes pre-incision doesn’t significantly reduce post-operative infection rates: JAMA study
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Proton-Pump Inhibitors Associated with Increased Mortality Risk
Is the use of proton-pump inhibitors (PPIs) associated with risk of mortality or combined risk of death or rehospitalization in older patients...
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Diabetes Mellitus Does Not Increase Risk of Surgical Complications after Elective Total Knee Replacement Surgery
Does uncontrolled diabetes mellitus increase risk for post-operative complications after elective joint replacement surgery?