Medical Grand Rounds

Sherif Mossad, MD
Department of Infectious Diseases, The Cleveland Clinic

Address: Sherif B. Mossad, MD, Department of Infectious Disease, S32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; email [email protected]

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Sherif Mossad, MD
Department of Infectious Diseases, The Cleveland Clinic

Address: Sherif B. Mossad, MD, Department of Infectious Disease, S32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; email [email protected]

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Sherif Mossad, MD
Department of Infectious Diseases, The Cleveland Clinic

Address: Sherif B. Mossad, MD, Department of Infectious Disease, S32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; email [email protected]

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Joseph H. Korn, MD
Director, Arthritis Center, Boston University School of Medicine; Chief, Rheumatology Section, Boston Medical Center

Address: Joseph H. Korn, MD, Chief, Rheumatology Section, Boston University Medical Center, 80 East Concord Street, Boston, MA 02118

The author has indicated that he has received grant or research support from the Actelion, Biogen, and Genzyme corporations and from the National Institutes of Health; serves as a consultant for the Actelion and Genzyme corporations; and is on the speaker’s bureau of the Actelion corporation.

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Joseph H. Korn, MD
Director, Arthritis Center, Boston University School of Medicine; Chief, Rheumatology Section, Boston Medical Center

Address: Joseph H. Korn, MD, Chief, Rheumatology Section, Boston University Medical Center, 80 East Concord Street, Boston, MA 02118

The author has indicated that he has received grant or research support from the Actelion, Biogen, and Genzyme corporations and from the National Institutes of Health; serves as a consultant for the Actelion and Genzyme corporations; and is on the speaker’s bureau of the Actelion corporation.

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Joseph H. Korn, MD
Director, Arthritis Center, Boston University School of Medicine; Chief, Rheumatology Section, Boston Medical Center

Address: Joseph H. Korn, MD, Chief, Rheumatology Section, Boston University Medical Center, 80 East Concord Street, Boston, MA 02118

The author has indicated that he has received grant or research support from the Actelion, Biogen, and Genzyme corporations and from the National Institutes of Health; serves as a consultant for the Actelion and Genzyme corporations; and is on the speaker’s bureau of the Actelion corporation.

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Steven M. Gordon, MD
Department of Infectious Diseases, Hospital Epidemiologist, The Cleveland Clinic

David L. Longworth, MD
Chairman, Department of Medicine, Baystate Medical Center, Springfield, Mass; Deputy Chairman, Department of Medicine, Tufts University School of Medicine, Boston

Address: Steven M. Gordon, MD, Department of Infectious Diseases, S31, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the authors but are not peer-reviewed.

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Steven M. Gordon, MD
Department of Infectious Diseases, Hospital Epidemiologist, The Cleveland Clinic

David L. Longworth, MD
Chairman, Department of Medicine, Baystate Medical Center, Springfield, Mass; Deputy Chairman, Department of Medicine, Tufts University School of Medicine, Boston

Address: Steven M. Gordon, MD, Department of Infectious Diseases, S31, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the authors but are not peer-reviewed.

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Steven M. Gordon, MD
Department of Infectious Diseases, Hospital Epidemiologist, The Cleveland Clinic

David L. Longworth, MD
Chairman, Department of Medicine, Baystate Medical Center, Springfield, Mass; Deputy Chairman, Department of Medicine, Tufts University School of Medicine, Boston

Address: Steven M. Gordon, MD, Department of Infectious Diseases, S31, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the authors but are not peer-reviewed.

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Barbara J. Messinger-Rapport, MD, PhD
Section of Geriatric Medicine, Department of General Internal Medicine, The Cleveland Clinic

Address: Barbara J. Messinger-Rapport, MD, PhD, Section of Geriatric Medicine, Department of Internal Medicine, A91, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195

The author has indicated that she is on the speaker’s bureau of the Pfizer corporation.

This paper discusses treatments that are experimental or that are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Barbara J. Messinger-Rapport, MD, PhD
Section of Geriatric Medicine, Department of General Internal Medicine, The Cleveland Clinic

Address: Barbara J. Messinger-Rapport, MD, PhD, Section of Geriatric Medicine, Department of Internal Medicine, A91, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195

The author has indicated that she is on the speaker’s bureau of the Pfizer corporation.

This paper discusses treatments that are experimental or that are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Barbara J. Messinger-Rapport, MD, PhD
Section of Geriatric Medicine, Department of General Internal Medicine, The Cleveland Clinic

Address: Barbara J. Messinger-Rapport, MD, PhD, Section of Geriatric Medicine, Department of Internal Medicine, A91, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195

The author has indicated that she is on the speaker’s bureau of the Pfizer corporation.

This paper discusses treatments that are experimental or that are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Gregg C. Fonarow, MD
Director, Ahmanson-UCLA Cardiomyopathy Center, Director Cardiology Fellowship Training Program, Co-Director, UCLA Preventative Cardiology Program, Associate Professor of Medicine, UCLA Division of Cardiology

Address: Gregg C. Fonarow, MD, Division of Cardiology, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095; e-mail: [email protected]

The author has indicated that he has received grant and research support from Pfizer, Merck, Bristol-Myers Squibb, and GlaxoSmithKline corporations.

His lecture at The Cleveland Clinic Division of Medicine Grand Rounds was funded in part by an unrestricted educational grant from Pfizer.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Gregg C. Fonarow, MD
Director, Ahmanson-UCLA Cardiomyopathy Center, Director Cardiology Fellowship Training Program, Co-Director, UCLA Preventative Cardiology Program, Associate Professor of Medicine, UCLA Division of Cardiology

Address: Gregg C. Fonarow, MD, Division of Cardiology, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095; e-mail: [email protected]

The author has indicated that he has received grant and research support from Pfizer, Merck, Bristol-Myers Squibb, and GlaxoSmithKline corporations.

His lecture at The Cleveland Clinic Division of Medicine Grand Rounds was funded in part by an unrestricted educational grant from Pfizer.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Gregg C. Fonarow, MD
Director, Ahmanson-UCLA Cardiomyopathy Center, Director Cardiology Fellowship Training Program, Co-Director, UCLA Preventative Cardiology Program, Associate Professor of Medicine, UCLA Division of Cardiology

Address: Gregg C. Fonarow, MD, Division of Cardiology, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095; e-mail: [email protected]

The author has indicated that he has received grant and research support from Pfizer, Merck, Bristol-Myers Squibb, and GlaxoSmithKline corporations.

His lecture at The Cleveland Clinic Division of Medicine Grand Rounds was funded in part by an unrestricted educational grant from Pfizer.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Steven M. Gordon, MD
Department of Infectious Disease, The Cleveland Clinic

Carlos M. Isada, MD
Department of Infectious Disease, The Cleveland Clinic

Address: Steven M. Gordon, MD, Department of Infectious Disease, S32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Steven M. Gordon, MD
Department of Infectious Disease, The Cleveland Clinic

Carlos M. Isada, MD
Department of Infectious Disease, The Cleveland Clinic

Address: Steven M. Gordon, MD, Department of Infectious Disease, S32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Steven M. Gordon, MD
Department of Infectious Disease, The Cleveland Clinic

Carlos M. Isada, MD
Department of Infectious Disease, The Cleveland Clinic

Address: Steven M. Gordon, MD, Department of Infectious Disease, S32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

This paper discusses therapies that are experimental or are not approved by the US Food and Drug Administration for the use under discussion.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Robert E. Hobbs, MD
Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, The Cleveland Clinic

Address: Robert E. Hobbs, MD, Department of Cardiovascular Medicine, F25, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

The author has indicated that he is on the speakers’ bureau of Scios, Inc.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Robert E. Hobbs, MD
Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, The Cleveland Clinic

Address: Robert E. Hobbs, MD, Department of Cardiovascular Medicine, F25, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

The author has indicated that he is on the speakers’ bureau of Scios, Inc.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Robert E. Hobbs, MD
Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, The Cleveland Clinic

Address: Robert E. Hobbs, MD, Department of Cardiovascular Medicine, F25, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; e-mail: [email protected]

The author has indicated that he is on the speakers’ bureau of Scios, Inc.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Stephen B. Levine, MD
Clinical Professor of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH; Co-Director, Center for Marital and Sexual Health, and President, Center for Sexual Health Research, Beachwood, OH

Address: Stephen B. Levine, MD, Center for Marital and Sexual Health, 3 Commerce Park Square, Suite 350, Beachwood, OH 44122-5402

The author has indicated that he has received grant or research support from Pfizer corporation, is a consultant for Lilly-ICOS, and is on the speakers' bureaus of the Consortium for Improvement in Erectile Function and Pfizer.

The presentation on which this article is based was supported by an unrestricted educational grant from Lilly-ICOS LLC.

This article discusses therapies that are not approved by the US Food and Drug Administration.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Stephen B. Levine, MD
Clinical Professor of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH; Co-Director, Center for Marital and Sexual Health, and President, Center for Sexual Health Research, Beachwood, OH

Address: Stephen B. Levine, MD, Center for Marital and Sexual Health, 3 Commerce Park Square, Suite 350, Beachwood, OH 44122-5402

The author has indicated that he has received grant or research support from Pfizer corporation, is a consultant for Lilly-ICOS, and is on the speakers' bureaus of the Consortium for Improvement in Erectile Function and Pfizer.

The presentation on which this article is based was supported by an unrestricted educational grant from Lilly-ICOS LLC.

This article discusses therapies that are not approved by the US Food and Drug Administration.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.

Stephen B. Levine, MD
Clinical Professor of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH; Co-Director, Center for Marital and Sexual Health, and President, Center for Sexual Health Research, Beachwood, OH

Address: Stephen B. Levine, MD, Center for Marital and Sexual Health, 3 Commerce Park Square, Suite 350, Beachwood, OH 44122-5402

The author has indicated that he has received grant or research support from Pfizer corporation, is a consultant for Lilly-ICOS, and is on the speakers' bureaus of the Consortium for Improvement in Erectile Function and Pfizer.

The presentation on which this article is based was supported by an unrestricted educational grant from Lilly-ICOS LLC.

This article discusses therapies that are not approved by the US Food and Drug Administration.

Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic. They are approved by the author but are not peer-reviewed.