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Inadequate pain relief in OA, high opioid use before TKA
Rates of inadequate pain relief in knee and hip OA, and high opioid use before total knee replacement surgery were reported in separate studies at...
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Weight gain may exacerbate structural damage in knee OA
Weight changes can have a significant effect on the structural progression of knee OA, according to new findings from Osteoarthritis Initiative...
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High comorbidity rate seen before osteoarthritis diagnosis
More than 40 medical conditions were positively associated with having a new diagnosis of osteoarthritis in a large, nested case-control study.
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Early meniscal surgery on par with active rehab in under 40s
Early meniscal surgery in people aged under 40 years was not better than an exercise and education program in the randomized controlled DREAM...
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Artificial intelligence aids assessment of UC activity, remission
AI systems have the potential to supplement the services of expert histopathologists and endoscopists rather than replace them.
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Endoscopic healing of Crohn’s disease could differ by biologic
Infliximab biosimilar and adalimumab resulted in better endoscopic healing rates than either vedolizumab or ustekinumab in a post-hoc pooled...
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IBD-VTE score serves as reminder to assess postdischarge risk
The new score is based on data from a large number of patients and uses eight readily available patient factors.
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LUCENT-1: Mirikizumab sees phase 3 success in UC treatment
Mirikizumab targets a subunit of interleukin 23, which has shown promise in other conditions.
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‘Superdonor’ samples don’t increase FMT success in ulcerative colitis
RESTORE-UC trial results contradict positive results seen in previous trials despite using highly standardized, “superdonor” samples.
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More exercise for people with hemophilia, experts advise
Physical activity can improve “quality of life” in people with hemophilia.
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What are the cardiorenal differences between type 1 and type 2 diabetes?
Heart failure may be as much, if not more of, a problem in people with type 1 diabetes as type 2 diabetes, researchers suggested.
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Estimating insulin resistance may help predict stroke, death in T2D
The estimated glucose disposal rate may be useful way to determine first stroke risk in type 2 diabetes.
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Aspirin lowered preeclampsia risk in real-world lupus study
A prospective, single-center study of pregnancies during 1995-2020 showed a reduced risk for preeclampsia among high-risk women with systemic...
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‘Multimorbidity’ more commonly seen in people with lupus
Two studies find that patients with either systemic or cutaneous disease have higher rates of multiple comorbidities, including those commonly...
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Lupus may confer higher risk of death from COVID-19
SLE had a greater impact on mortality and other poor outcomes than did all the other comorbidities considered in a cross-sectional study of COVID-...