Sharon Worcester is an award-winning medical journalist for MDedge News. She has been with the company since 1996, first as the Southeast Bureau Chief (1996-2009) when the company was known as International Medical News Group, then as a freelance writer (2010-2015) before returning as a reporter in 2015. She previously worked as a daily newspaper reporter covering health and local government. Sharon currently reports primarily on oncology and hematology. She has a BA from Eckerd College and an MA in Mass Communication/Print Journalism from the University of Florida. Connect with her via LinkedIn and follow her on twitter @SW_MedReporter.
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Analysis of early onset cancers suggests need for genetic testing
- Author:
- Sharon Worcester
The prevalence of germline mutations was significantly higher in patients with early onset cancers than in those with young adult cancers.
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AI markers can predict progression, survival in prostate cancer
- Author:
- Sharon Worcester
Artificial intelligence–based Gleason scores correlated with pathologists’ Gleason scores.
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Lipophilic statins linked to lower mortality in ovarian cancer
- Author:
- Sharon Worcester
Lipophilic statin use was associated with a 43% reduction in mortality.
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Novel SERD, LSZ102, shows promise for pretreated ER+ breast cancer
- Author:
- Sharon Worcester
LSZ102 was relatively well tolerated as a single agent and in combination with ribociclib and alperisib.
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Tumor markers are ‘valuable’ for relapse detection in rare CNS tumors
- Author:
- Sharon Worcester
Among evaluable patients, 92% of relapses were detectable by tumor markers.
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Sequential chemoradiation improves DFS in early-stage cervical cancer
- Author:
- Sharon Worcester
The 3-year disease-free survival rate was significantly higher among patients who received sequential chemoradiation than among patients who...
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Immunotherapy combo improves ORR, PFS in PD-L1+ NSCLC
- Author:
- Sharon Worcester
Adding tiragolumab to atezolizumab led to “clinically meaningful” improvements in patients with PD-L1–positive non–small cell lung cancer.
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No OS benefit with gefitinib vs. chemo for EGFR+ NSCLC
- Author:
- Sharon Worcester
Adjuvant gefitinib improved disease-free survival, but not overall survival, when compared with standard chemotherapy.
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Addressing racism, bias in the American maternal mortality crisis
- Author:
- Sharon Worcester
“I think the most important thing you can do is really consider a patient a partner in the care you give them.”
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Poziotinib provides ‘modest but meaningful’ efficacy in NSCLC subgroup
- Author:
- Sharon Worcester
About 15% of patients achieved a response with poziotinib and 65% had a decrease in tumor size.
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ALTERNATE trial: No fulvestrant benefit in locally advanced ER+ HER2– breast cancer
- Author:
- Sharon Worcester
The endocrine-sensitive disease rate was similar whether patients received anastrozole alone, fulvestrant alone, or fulvestrant plus anastrozole...
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LOTUS: Ipatasertib plus paclitaxel may prolong OS in TNBC
- Author:
- Sharon Worcester
Ipatasertib provided a “clinically meaningful,” but not statistically significant, 9-month improvement in median overall survival.
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Novel penclomedine shows promise for some AYAs with CNS cancers
- Author:
- Sharon Worcester
Two patients who responded to the treatment were in their 59th month of survival at last follow-up.
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Universal CAR-T therapy produces CRs in relapsed/refractory T-ALL
- Author:
- Sharon Worcester
All five patients studied achieved a complete response, though one patient had a morphological relapse.
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MRD surveillance can detect relapse before imaging in early-stage NSCLC
- Author:
- Sharon Worcester
Relapse occurred in 9 of 10 patients who were positive for minimal residual disease but had no evidence of relapse on imaging.